Core Insights - The Ministry of Industry and Information Technology of China has released the first batch of iconic products in biomanufacturing, with "1,4-butanediamine" developed by China Resources Double Crane Synthetic Biology Research Institute and industrialized by Shenzhou Biotechnology being included in the list [1][5]. Group 1: Product Overview - "1,4-butanediamine" is recognized as an important chemical raw material with extensive applications in high-performance plastics (such as nylon 46), pharmaceuticals, and agricultural chemicals [5]. - The product has historically faced technical and supply challenges, with traditional chemical synthesis methods relying on petroleum-based raw materials and causing environmental pollution [5]. Group 2: Technological Advancements - China Resources Double Crane Synthetic Biology Research Institute has developed a new metabolic pathway for "1,4-butanediamine," establishing an efficient cell factory that enhances fermentation, catalysis, and separation extraction processes [5][6]. - The product has successfully completed pilot testing at Shenzhou Biotechnology's platform, achieving an annual production capacity of hundreds of tons [5]. Group 3: Industrial Collaboration and Achievements - China Resources Double Crane has collaborated with China Resources Chemical Materials to successfully complete small-scale industrialization of high-temperature nylon 46 using bio-based "1,4-butanediamine" as a raw material [6]. - The performance indicators of the polymerized high-temperature nylon 46 have reached advanced levels compared to similar foreign products [6]. Group 4: Strategic Importance - The inclusion of this product in the biomanufacturing iconic product list highlights the significant achievements of China Resources Double Crane in overcoming high technical barriers [6]. - This breakthrough is crucial for addressing national technological challenges and provides strong support for achieving self-sufficiency in strategic materials like high-temperature nylon 46 in China [6].