AKR1C3酶活化平台
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浙江海正药业股份有限公司第十届董事会第七次会议决议公告
Shang Hai Zheng Quan Bao· 2025-09-16 20:38
Core Viewpoint - Zhejiang Haizheng Pharmaceutical Co., Ltd. has signed an exclusive licensing and strategic cooperation agreement with Shenzhen Aixin Dawei Pharmaceutical Technology Co., Ltd. to enhance its innovation drug development capabilities and create new value growth points [1][3]. Group 1: Licensing Agreement - The agreement grants Haizheng exclusive rights to the globally innovative small molecule prodrug AST-3424 within the specified regions, including mainland China, Hong Kong, and Macau [1]. - Haizheng is authorized to research, develop, register, produce, and commercialize the licensed product, and will be the sole applicant for market approval in the cooperation area [1][3]. - A non-competition clause prohibits Aixin Dawei and its affiliates from engaging in competitive activities in the cooperation area during the agreement's term [2]. Group 2: Financial Terms - Haizheng will pay an upfront fee and milestone payments totaling no more than 240 million RMB based on the achievement of development milestones [3]. - Upon the product's first approval for sale in the cooperation area, Haizheng will pay annual royalties based on a percentage of net sales and milestone bonuses based on annual sales performance [4]. Group 3: Strategic Cooperation on AKR1C3 Enzyme Activation Platform - The agreement includes a strategic cooperation on Aixin Dawei's AKR1C3 enzyme activation platform, with a two-year option period for Haizheng to exercise its rights [5]. - Aixin Dawei is responsible for developing specified drugs using the AKR1C3 platform and advancing them to obtain clinical trial approval in mainland China [5]. - Any intellectual property developed during the cooperation will be exclusively owned or licensed to Haizheng [5][6]. Group 4: Charitable Donation - Haizheng's subsidiary, Huizheng (Shanghai) Pharmaceutical Technology Co., Ltd., will donate 200,000 RMB to support a prostate screening charity project in Nanjing [7]. - The donation is made from the company's own funds and does not significantly impact current or future performance [7].
海正药业:与艾欣达伟签署产品独家许可及战略合作协议
Xin Lang Cai Jing· 2025-09-16 10:56
Core Viewpoint - The company, Haizheng Pharmaceutical (600267.SH), has signed an exclusive licensing and strategic cooperation agreement with Shenzhen Aixin Dawei Pharmaceutical Technology Co., Ltd. to introduce the globally innovative small molecule prodrug AST-3424 in specified regions [1] Group 1 - The company will pay an upfront fee to Aixin Dawei and will also pay milestone payments based on the actual achievement of development milestones, with total costs not exceeding 240 million yuan [1] - The cooperation area includes mainland China, Hong Kong Special Administrative Region, and Macau Special Administrative Region [1] - The company will also engage in strategic cooperation with Aixin Dawei on the AKR1C3 enzyme activation platform [1]