Using AI, CDT Equity Inc. identifies a novel therapeutic indication for its lead programmes, supported by successful pre-clinical trial dataNAPLES, Fla. and CAMBRIDGE, United Kingdom, Aug. 26, 2025 (GLOBE NEWSWIRE) -- CDT Equity Inc. (Nasdaq: CDT) (“CDT” or the “Company”) today announces that it has successfully identified a new biological target and novel therapeutic indication for its lead programme, AZD1656 (and its derivatives), following positive data from pre-clinical studies. This affirms the Company ...

Core Insights - Conduit Pharmaceuticals has filed four new patent applications for its key assets AZD1656 and AZD5658, marking the first patent filings for AZD5658, which significantly expands the company's intellectual property portfolio [1][6] - The new patents are based on combinations of Conduit's lead assets with existing therapies, identified through AI-led analysis in collaboration with Sarborg Limited, enhancing the company's ability to generate novel, data-driven intellectual property [2][6] - The Chief Scientific Officer of Conduit Pharmaceuticals emphasized that these filings validate the progress made through the partnership with Sarborg, uncovering therapeutic combinations with substantial commercial potential [3] Company Overview - Conduit Pharmaceuticals is a clinical-stage life science company that employs an efficient model for compound development, focusing on acquiring and funding Phase 2-ready assets [4] - The company utilizes a platform-driven approach powered by artificial intelligence and cybernetics, aiming for exits through third-party licensing deals after successful clinical trials [4] - The leadership team includes experienced executives such as Dr. Andrew Regan and Dr. Freda Lewis-Hall, indicating a strong foundation for the company's innovative approach [4]

Core Insights - Conduit Pharmaceuticals has entered a joint development agreement with Manoira Corporation to evaluate its glucokinase activators AZD1656 and AZD5658 for veterinary applications, particularly in animal osteoarthritis [1][2][3] - The collaboration aims to generate preclinical data that will inform Conduit's human clinical programs while retaining full ownership of all related intellectual property [3][5][6] - This partnership opens new revenue streams in the growing $15 billion animal health market, projected to grow at a CAGR of 6.5% through 2027 [7][6] Company Strategy - The agreement highlights Conduit's commitment to innovative collaborations that maximize resource efficiency and pipeline potential [4] - By leveraging Manoira's expertise, Conduit aims to accelerate the development of AZD1656 and explore cross-species value through targeted programs [5][6] - The partnership is designed to enhance Conduit's competitive edge in glucokinase activator therapies and create a dual-track value proposition for shareholders [3][7] Financial Aspects - Manoira will fund all development activities, while Conduit will issue an upfront consideration of $500,000 through the issuance of 154,799 shares of common stock [8] - The collaboration is expected to reduce development timelines and costs for human clinical trials, enhancing the probability of success for AZD1656 in human indications [7][6] - The joint development agreement allows Conduit to retain exclusive rights and ownership of all new intellectual property related to AZD1656 and AZD5658 for human applications [5][4]

Core Insights - Conduit Pharmaceuticals has secured a composition of matter patent for its lead asset, AZD1656, from the Korean Intellectual Property Office, enhancing its global intellectual property position and facilitating clinical development and strategic partnerships [1][2] - The patent approval follows similar grants in the U.S., Japan, and Australia, indicating a robust international patent strategy that supports Conduit's growth in the Asia-Pacific pharmaceutical market [1][2] - The company aims to leverage its innovative approach to compound development, utilizing artificial intelligence and cybernetics, to create long-term value through global partnerships and licensing deals [2] Company Overview - Conduit Pharmaceuticals is a clinical-stage life science company focused on developing Phase 2-ready assets through an integrated platform-driven approach [2] - The leadership team, including Dr. Andrew Regan and Dr. Freda Lewis-Hall, emphasizes a departure from traditional pharmaceutical business models by seeking exits through third-party licensing after successful clinical trials [2]

Core Viewpoint - Conduit Pharmaceuticals Inc. has authorized a share repurchase program to buy back up to $1,000,000 of its common stock, believing the current market price does not reflect its underlying value [1][4]. Share Repurchase Program - The program allows Conduit to repurchase shares through open market transactions or other methods, adhering to SEC Rule 10b-18, with purchases executed by The Benchmark Company [2]. - There is no obligation for the company to acquire a specific amount of stock, and the program has no fixed expiration date, allowing for adjustments or termination at any time [3]. Company Overview - Conduit is a clinical-stage life science company focused on an efficient model for compound development, acquiring and funding Phase 2-ready assets [4]. - The company employs a platform-driven approach powered by artificial intelligence and cybernetics, aiming for exits through third-party license deals after successful clinical trials [4]. - The leadership team includes experienced pharmaceutical executives, indicating a strong foundation for the company's innovative approach [4].

Core Insights - Conduit Pharmaceuticals has expanded its partnership with Sarborg to utilize advanced machine learning for analyzing clinical data from AstraZeneca-acquired assets, aiming to optimize development pathways and uncover new insights [1][2] Group 1: Partnership Details - The new agreement allows Sarborg to apply its proprietary machine learning algorithms to analyze Conduit's clinical and safety data, focusing on identifying missed insights and potential drug repurposing opportunities [2] - The collaboration includes a non-exclusive, non-transferable license for Conduit to access Sarborg's advanced algorithmic platform for six months, building on an existing Services Agreement [3] Group 2: Strategic Goals - The partnership aims to re-evaluate historical clinical trial data to identify specific patient subgroups that may have shown therapeutic benefits, which could refine Conduit's future clinical development strategy [2] - Dr. David Tapolczay, CEO of Conduit Pharmaceuticals, emphasized the commitment to leveraging data science to maximize the potential of their pipeline, particularly for key assets like AZD1656 [4] Group 3: Company Overview - Conduit Pharmaceuticals is a clinical-stage life science company focused on an efficient model for compound development, acquiring and funding Phase 2-ready assets while utilizing AI and cybernetics [4] - The company aims for exits through third-party license deals following successful clinical trials, representing a departure from traditional pharma/biotech business models [4]

Group 1: Company Overview - Conduit Pharmaceuticals has secured a composition of matter patent from the USPTO for its lead asset, AZD1656, a Glucokinase Activator targeting autoimmune disorders such as Lupus and ANCA Vasculitis, positioning the company for clinical development and strategic partnerships [1][2] - The company is focused on developing Phase 2-ready assets and employs an integrated platform-driven approach powered by artificial intelligence (AI) and cybernetics, aiming for exit through third-party license deals following successful clinical trials [4] Group 2: Market Potential - The U.S. autoimmune disease market is projected to reach $150 billion by 2030, with Lupus affecting approximately 1.5 million Americans and ANCA Vasculitis impacting 200,000 patients annually, indicating a growing demand for innovative treatments [2] - Conduit's patent protection, which provides up to 20 years of exclusivity in the U.S., reinforces its competitive positioning and opens opportunities for commercial and strategic licensing partnerships [2][3] Group 3: Intellectual Property - Composition of matter patents are considered the gold standard in pharmaceutical intellectual property, offering strong market exclusivity and protection against generic competition [3] - The newly granted patent, along with existing approvals in Japan and Australia, positions Conduit favorably in three major pharmaceutical markets, with pending applications in Europe and other regions expected to expand its footprint [2]