Key Takeaways ADMA posted $114.8M in Q1 revenues, driven by record Asceniv sales. The new process ups IG output by 20%, supporting ADMA's $500M revenue target for 2025. Despite gains, ADMA trades at 7.68x sales and faces EPS estimate cuts amid stiff plasma therapy competition. ADMA Biologics (ADMA) markets plasma-derived biologics for the treatment of immune deficiencies and prevention of certain infectious diseases.ADMA’s lead product, Asceniv, is a plasma-derived Intravenous Immune Globulin that contain ...

Core Insights - ADMA Biologics and Takeda are prominent players in the plasma-derived immunoglobulin sector, with ADMA focusing on treatments for immune deficiencies and Takeda having a diversified portfolio across various therapeutic areas [1][8]. ADMA Biologics - ADMA markets three FDA-approved plasma-derived products: Bivigam, Asceniv, and Nabi-HB, targeting immune deficiencies and infectious diseases [3][10]. - Asceniv, ADMA's lead product, is a plasma-derived IVIG that contains polyclonal antibodies, crucial for neutralizing microbes [4][5]. - Record demand for Asceniv was noted in Q1, with expectations for revenue growth through 2025 and plans for a pediatric label expansion filing by mid-2025 [6][10]. - ADMA anticipates proof-of-concept data for its pipeline program SG-001 by the end of 2025, with potential annual revenues of $300-500 million [7]. Takeda - Takeda's plasma-derived therapies (PDT) business unit has shown 9% growth in 2024, supported by a broad immunoglobulin portfolio including Hyqvia, Cuvitru, and Gammagard [8][10]. - Hyqvia is notable for being the only subcutaneous IG treatment for primary immunodeficiencies, requiring fewer infusions [11]. - Takeda is actively developing next-generation immunoglobulin products and has partnered with other companies to enhance its pipeline [13][14]. Financial Estimates and Performance - The Zacks Consensus Estimate for ADMA's 2025 sales indicates an 18.61% year-over-year increase, while EPS estimates have shown mixed movements [15]. - In contrast, Takeda's 2025 sales estimates suggest a 2.80% decrease, with EPS showing a 6.21% improvement [16]. - Year-to-date, Takeda's stock has outperformed ADMA, with gains of 13.91% compared to ADMA's 4.1% [18]. - Valuation metrics indicate ADMA is trading at 21.79X forward earnings, significantly higher than Takeda's 9.03X [18]. Investment Considerations - Takeda is recognized for its stability and broad portfolio, making it a safer investment choice, while ADMA's growth potential is tied to the expansion of Asceniv [21][22]. - Despite Takeda's current ranking as a "Sell," ADMA's revenue potential from Asceniv positions it as a more attractive investment opportunity at present [22][23].

Key Takeaways ADMA saw record demand for Asceniv and plans a 2025 filing to expand into pediatric use. Label expansion and new patient starts are expected to drive growth in Asceniv sales. ADMA trades at 8.75X forward sales, above its historical average and industry valuation levels.ADMA Biologics (ADMA) markets plasma-derived biologics for the treatment of immune deficiencies and the prevention of certain infectious diseases.ADMA’s lead product, Asceniv, is a plasma-derived Intravenous Immune Globulin th ...

ADMA Biologics (ADMA) has been a consistent market outperformer in recent times. Shares have gained 17.2% in the past three months against the industry’s decline of 10.6%. The stock has also outperformed the sector and the S&P 500 in this timeframe.ADMA Outperforms Industry, Sector & S&P 500Image Source: Zacks Investment ResearchADMA Biologics markets plasma-derived biologics for the treatment of immune deficiencies and the prevention of certain infectious diseases.Though the first-quarter results (reported ...

Core Viewpoint - ADMA Biologics and Grifols are prominent players in the plasma-derived therapies market, each with unique strengths and growth prospects, making stock selection challenging [1][2]. Company Overview ADMA Biologics - ADMA specializes in plasma-derived biologics for treating immune deficiencies and preventing infectious diseases, with three FDA-approved products: Bivigam, Asceniv, and Nabi-HB [3][6]. - Asceniv, the lead product, is a plasma-derived IVIG that contains polyclonal antibodies to neutralize microbes [4][5]. - The company anticipates significant revenue growth from Asceniv, driven by record demand and plans for a new R&D program, SG-001, which could generate $300-500 million in annual revenues [6]. Grifols - Grifols is a global leader in plasma-derived medicines, developing a wide range of biological therapies targeting various immunological conditions [7][8]. - The company reported sales of €7.2 billion in 2024, reflecting a 10.3% increase, and is recognized as the largest producer of A1PI [9][10]. - Grifols has a diverse portfolio and is positioned for consistent growth due to strong demand and operational execution [11]. Financial Estimates ADMA Biologics - The Zacks Consensus Estimate for ADMA's 2025 sales indicates an 18.61% year-over-year increase, with EPS expected to improve by 36.73% [12]. - Recent estimate revisions show a decline in EPS estimates for 2025 but an increase for 2026 [13]. Grifols - The Zacks Consensus Estimate for Grifols' 2025 sales suggests a 3.78% increase, with EPS expected to rise by 296% [12]. - EPS estimates for both 2025 and 2026 have seen upward revisions in the past 60 days [15]. Price Performance and Valuation - Year-to-date, ADMA shares have increased by 15.9%, outperforming Grifols' 10.6% rise, while the industry has declined by 4.1% [16]. - In terms of valuation, ADMA trades at 25.48X forward earnings, significantly higher than Grifols' 7.19X [16]. Investment Recommendation - ADMA shows steady growth driven by Asceniv demand, while Grifols, with a broader portfolio and better valuation, is considered a more favorable investment choice at present [20][21][22].

Core Viewpoint - ADMA Biologics reported lower-than-expected first-quarter results, with adjusted earnings per share of 14 cents missing the consensus estimate of 16 cents, and revenues of $114.8 million, up 40% year over year, also falling short of the expected $119 million. Despite this, the company raised its revenue guidance for 2025 and 2026 [1][8]. Group 1: Financial Performance - The first-quarter adjusted earnings per share were 14 cents, missing the Zacks Consensus Estimate of 16 cents [1]. - Revenues for the first quarter were $114.8 million, which is a 40% increase year over year but below the expected $119 million [1]. - ADMA updated its revenue guidance, now expecting over $500 million in 2025 and $625 million in 2026, an increase from previous estimates of over $490 million and $605 million respectively [8]. Group 2: Product and Market Insights - ADMA markets plasma-derived biologics, including three FDA-approved products: Bivigam, Asceniv, and Nabi-HB, targeting immune deficiencies and infectious diseases [3]. - Asceniv, the lead product, is a plasma-derived IVIG that contains polyclonal antibodies to treat primary immunodeficiency disease (PIDD) [4][5]. - Demand for Asceniv was record high in the first quarter, with expectations for revenue share to expand throughout 2025 and beyond due to new patient starts and increased penetration in existing institutions [6]. Group 3: Growth Prospects - ADMA is developing SG-001, a hyperimmune globulin targeting S. pneumonia, with potential annual revenues of $300-500 million expected by 2025 [7]. - The company anticipates significant growth opportunities in the underserved immune-compromised and co-morbid patient population, despite competition from standard-of-care therapies [19]. - The recent FDA approval for an innovative yield enhancement production process supports revenue growth and margin expansion opportunities [21]. Group 4: Stock Performance and Valuation - ADMA's shares have surged 37.7% year to date, outperforming the industry, which has declined by 7.4% [11]. - The current price/sales ratio for ADMA is 10.46x forward sales, significantly higher than its historical mean of 3.32x and the industry average of 1.65x, indicating a high valuation [14].

Core Insights - ADMA Biologics reported a strong financial performance in Q1 2025, with total revenue of $114.8 million, representing a 40% year-over-year increase, and adjusted total revenue of $118.6 million, indicating approximately 45% growth when excluding one-time product withdrawals [1][9] - The company achieved a GAAP net income of $26.9 million, a 51% increase year-over-year, and an adjusted net income of $33.3 million, reflecting an 87% year-over-year growth [1][11] - Adjusted EBITDA for the quarter was $47.9 million, marking an 81% increase compared to the same period last year [1][12] Financial Performance - Total cash and receivables grew to approximately $171 million, providing a strong liquidity position [1][3] - The gross profit for Q1 2025 was $61.1 million, translating to a gross margin of 53.2%, up from 47.8% in Q1 2024 [10] - The company has increased its total revenue guidance for FY 2025 to more than $500 million and for FY 2026 to more than $625 million [1][7] Strategic Developments - The FDA approved a yield enhancement production process, expected to increase production output by 20% from the same starting plasma volume, which is anticipated to support revenue growth and margin expansion [1][3] - ADMA has authorized a $500 million share repurchase program, representing approximately 8% of its current market capitalization, aimed at enhancing stockholder value [1][8] - A debt reorganization has reduced ADMA's cost of debt capital by 1.1%, further strengthening its financial position [1][3] Market Position and Outlook - The company expects total annual revenues to exceed $1.1 billion by 2030, with significant earnings growth anticipated from current margin levels [2][7] - ADMA's U.S.-based manufacturing and supply chain provide insulation from geopolitical and global trade challenges, positioning the company favorably against multinational competitors [3][7] - The demand for ASCENIV, one of ADMA's key products, continues to trend towards record highs, with expectations for increased market penetration and new patient starts [4][7]

Core Viewpoint - ADMA Biologics is expected to report first-quarter 2025 results on May 7, with sales estimated at $119.1 million and earnings at 16 cents per share, reflecting a positive trend in earnings estimates for 2025 and 2026 [1][2][16]. Financial Performance - The earnings estimate for 2025 has increased to 71 cents from 69 cents per share over the past 60 days, while the estimate for 2026 has improved to 93 cents from 87 cents [1][2]. - ADMA has a mixed earnings surprise history, beating estimates in three of the last four quarters with an average surprise of 32.8%, although it missed estimates by 6.67% in the most recent quarter [2][3]. Product Overview - ADMA markets plasma-derived biologics, including three FDA-approved products: Bivigam, Asceniv, and Nabi-HB, aimed at treating immune deficiencies and preventing infectious diseases [6][17]. - Asceniv, the lead product, is a plasma-derived IVIG that contains polyclonal antibodies to neutralize microbes and prevent infections [7][8]. Sales and Growth Drivers - Increased sales of Asceniv are expected to drive revenue growth in the first quarter, supported by a favorable mix of high-margin immunoglobulin sales [9]. - ADMA anticipates significant growth in revenues, projecting over $490 million in 2025 and $605 million in 2026, with net income expected to exceed $175 million in 2025 [16]. Market Position and Strategy - ADMA has entered into long-term high-titer plasma supply contracts, increasing access to raw materials and potentially achieving $1 billion in annual revenues by 2030 [14]. - The company competes with Takeda and Grifols in the U.S. plasma-derived products market and is positioned for substantial growth in the underserved immune-compromised patient population [17][18]. Valuation - ADMA's shares currently trade at a price/sales ratio of 10.59x forward sales, significantly higher than its historical mean of 3.32x and the industry average of 1.76x, indicating a premium valuation [12]. Price Performance - ADMA's stock has surged 38.8% year-to-date, outperforming the industry, which has declined by 2.7% [10].

Conference Call Scheduled for May 7, 2025, at 4:30 p.m. ETRAMSEY, N.J. and BOCA RATON, Fla., April 30, 2025 (GLOBE NEWSWIRE) -- ADMA Biologics, Inc. (Nasdaq: ADMA) (“ADMA” or the “Company”), a U.S. based, end-to-end commercial biopharmaceutical company dedicated to manufacturing, marketing, and developing specialty biologics, today announced that it will report first quarter 2025 financial results on May 7, 2025, after the U.S. financial markets close. ADMA’s management team will host a live conference call ...

Approval Supports Revenue Growth and Margin Expansion Opportunity, and Substantially Increases Peak Production Output Capacity First U.S. Regulatory Approval of Innovative IG Yield Enhancement Process Highlights ADMA's Uniquely Efficient Internal R&D Engine, Spanning Production and Product Development Capabilities Anticipate Approximately 20% Production Output Enhancement from Same Starting Plasma Volume About ADMA Biologics, Inc. (ADMA) ADMA Biologics is a U.S. based, end-to-end commercial biopharmaceutica ...