Workflow
CM512(TSLPxIL13 双抗)
icon
Search documents
康诺亚-B(02162):司普奇拜单抗销售快速增长,后续管线研发顺利推进
Guoxin Securities· 2025-08-29 14:07
Investment Rating - The investment rating for the company is "Outperform the Market" [4][17]. Core Views - The sales of Siponimod have experienced rapid growth, with revenue reaching 499 million yuan in the first half of 2025, representing an increase of 812%. The sales of Siponimod alone accounted for 169 million yuan [7][17]. - The company reported a loss of 79 million yuan in the first half of 2025, an improvement from a loss of 337 million yuan in the same period last year. Research and development expenses increased by 9% to 360 million yuan, while sales expenses surged by 492% to 138 million yuan [7][17]. - The company has approximately 2.8 billion yuan in cash as of mid-2025 [7]. Summary by Sections Sales Growth and Product Pipeline - Siponimod was approved for market launch in September 2024 and has received approval for three indications: atopic dermatitis, chronic rhinosinusitis with nasal polyps, and seasonal allergic rhinitis. The unique indications in the nasal category are exclusive to China, which is expected to drive sales growth [13][17]. - Ongoing clinical trials for additional indications, including nodular prurigo and atopic dermatitis in adolescents and children, are in Phase 3 [13]. Future Revenue Projections - The revenue forecast for the company has been revised upwards due to successful licensing transactions, with expected revenues of 827 million yuan, 1.095 billion yuan, and 2.046 billion yuan for 2025, 2026, and 2027, respectively [17]. - The projected net profit for the parent company is expected to improve to -490 million yuan in 2025, -576 million yuan in 2026, and a profit of 53 million yuan in 2027 [17]. Clinical Development Progress - The company’s pipeline includes CMG901 (CLDN18.2 ADC), which has been licensed to AZ and is currently undergoing global registration clinical trials. Other candidates like CM512 (TSLPxIL13 bispecific antibody) are in Phase 2 trials for various indications [2][13].