Bio-Techne Conference Call Summary Company Overview - **Company**: Bio-Techne (NasdaqGS: TECH) - **Date**: November 10, 2025 - **Key Speakers**: Kim Kelderman, Jim Hippel, Dave Clair Key Points Financial Performance - **Organic Growth**: The company reported a negative 1% organic growth in the top line, primarily due to a $7 million impact from larger orders in GMP proteins not repeating year over year [3][10] - **EBITDA Margins**: The EBITDA margin stood at 29.9%, indicating strong operational performance despite headwinds [6] Market Dynamics - **Pharmaceutical Market**: Continued to show double-digit growth, with positive trends in funding and deal activity [4] - **Academic Market**: Flat performance, but core business showed strength [4] - **Regional Performance**: - **Europe**: Mid-single digit growth as expected [4] - **U.S.**: Negative low single digits, but showing improvement [4] - **China**: Two consecutive quarters of growth, indicating a positive trend [4] Business Segments - **Core Business**: Flat performance, recovering from previous quarters [5] - **Growth Verticals**: - **Gene Therapy**: Added numerous customers in cell therapy [5] - **Protein Analytics**: Mid-single digit growth [5] - **Molecular Diagnostics**: Mid-single digit growth, with a significant 34% growth in the same quarter last year [5] GMP Proteins - **Customer Concentration**: Two major customers accounted for a significant portion of GMP protein revenue, with a $12 million headwind expected in the next quarter [16] - **Market Conditions**: The biotech market showed improvement, moving from negative 30% to negative 19% [11] Product Innovations - **New Product Introductions**: Strong pipeline of new products across various lines, including ELA and Western Blot instruments, expected to drive future growth [32][33] - **Organoid Market**: The organoid business is projected to grow significantly, with a current estimated revenue of $50 million and a CAGR of 20% [51][52] Future Outlook - **Growth Projections**: The company anticipates low single-digit growth for the year, with expectations for improvement in the second half due to easing headwinds and market stabilization [55][59] - **China Market**: Optimism about sustained growth in China, with a focus on gradual recovery [60][61] Margin Expansion Opportunities - **Divestitures**: The divestiture of Exosome and exiting low-margin businesses like fetal bovine serum are expected to enhance margins [62] - **Operational Efficiency**: Ongoing efforts to optimize manufacturing and improve collaboration across business units are anticipated to drive margin improvements [63][64] Conclusion - Bio-Techne is navigating a challenging market environment with a focus on innovation, customer acquisition, and operational efficiency. The company is optimistic about future growth, particularly in the organoid and cell therapy markets, while managing the impacts of customer concentration and market fluctuations.

Industry Overview - The global big data market is projected to grow from $199.63 billion in 2024 to $573.47 billion by 2033, with a CAGR of 12.44% [2] - The big data analytics market is expected to increase from $277.14 billion in 2024 to $1,045.26 billion by 2033, at a CAGR of 13.7% [3] Company Highlights NVIDIA Corp. (NVDA) - NVIDIA reported strong second-quarter fiscal 2026 earnings, with quarterly sales expected to reach $54 billion, +/- 2% [8] - The company anticipates that resuming H20 chip sales in China could add $2 to $5 billion in the third quarter [8] - NVIDIA's revenue and earnings growth rates are expected to be 56.3% and 48.5%, respectively, for the current year [12] Palantir Technologies Inc. (PLTR) - Palantir's second-quarter earnings surpassed $1 billion for the first time, driven by its AI-powered data mining and analytics [13] - The company has increased its full-year revenue guidance to between $4.142 billion and $4.150 billion [16] - Expected revenue and earnings growth rates for Palantir are 45.6% and 58.5%, respectively, for the current year [16] Microsoft Corp. (MSFT) - Microsoft has capitalized on AI business momentum, with strong demand for Office 365 and Azure cloud services [17][18] - Azure achieved over $75 billion in annual revenues with a growth rate of 34% [20] - Expected revenue and earnings growth rates for Microsoft are 14% and 12.5%, respectively, for the current year [21] International Business Machines Corp. (IBM) - IBM is experiencing healthy demand for hybrid cloud and AI solutions, bolstered by its acquisition of Hakkoda [23] - The company’s expected revenue and earnings growth rates are 6.4% and 7.7%, respectively, for the current year [26] F5 Inc. (FFIV) - F5 is benefiting from strong software growth and increasing demand for application security in multi-cloud environments [27] - The company has made six acquisitions over the past five years to enhance its security capabilities [28] - Expected revenue and earnings growth rates for F5 are 3.9% and 4%, respectively, for the next year [30]