Financial Data and Key Metrics Changes - Elanco reported revenue of $1,241 million, representing a 5% increase on a reported basis and an 8% organic constant currency growth driven by a 5% increase in volume and a 3% contribution from price [43][44] - Adjusted EBITDA was $238 million, a decrease of $37 million year-over-year, while adjusted EPS was $0.26, down $0.04 year-over-year [48] - The net debt leverage ratio improved to four times, reflecting strong second quarter results and working capital discipline [8][48] Business Line Data and Key Metrics Changes - U.S. Pet Health revenue increased by 11%, driven by demand for key innovation products and contributions from the vaccine portfolio [11][44] - International Pet Health grew by 7% in organic constant currency, led by demand for AdTab and ZENRELIA [12][44] - The U.S. Farm Animal business grew by 5%, while international farm animal revenue increased by 6% in organic constant currency [13][45] Market Data and Key Metrics Changes - The overall pet health market is experiencing double-digit growth, with significant contributions from innovative products like Credelio Quattro and ZENRELIA [20][21] - The dermatology market is growing rapidly, with ZENRELIA gaining market share and achieving a reorder rate of almost 80% [21][27] - The farm animal market is supported by increased demand for animal protein, with Experior showing rapid adoption and strong customer retention [30][31] Company Strategy and Development Direction - The company is focused on growth, innovation, and cash generation, with a clear path to becoming a leader in pet health and farm animal markets [6][10] - Elanco is increasing its full-year innovation revenue expectations by $60 million, reflecting strong performance across multiple products [8][15] - The Elanco Ascend initiative aims to drive efficiencies and improve productivity through automation and AI [39][40] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in navigating external uncertainties and executing long-term growth strategies, with a strong position to raise revenue and earnings outlook [10][56] - The company anticipates organic constant currency growth of 5% to 6% for the full year, with adjusted EBITDA guidance raised to $850 million to $890 million [10][50] - Management highlighted the importance of innovation in stabilizing the base business and driving future growth [10][76] Other Important Information - The company is actively managing tariff risks and has implemented strategies to mitigate potential impacts, estimating a net impact of $10 million to $14 million for 2025 [9][53] - Elanco's cash generated from operations was $237 million in the quarter, compared to $200 million in the same quarter last year [48] Q&A Session Summary Question: Can you talk about some of the accelerated investments being made in the business? - Management indicated that investments are focused on DTC spending for Credelio Quattro and R&D for upcoming blockbusters, with a strong market response supporting these initiatives [61][62] Question: What are the expectations for the sustainability of mid-single-digit growth for the company? - Management believes that the base business is stable, with innovation expected to drive additional growth, and emphasized the importance of maximizing the potential of their product portfolio [72][76] Question: Can you provide insight into the main contributors to the increased innovation sales target? - Management noted that growth is being led by multiple products, particularly Credelio Quattro, and highlighted the seasonal nature of some products [81] Question: How does the company plan to allocate upside in a given quarter? - Management stated that they will monitor the effectiveness of investments in sales and marketing or R&D and adjust spending accordingly [83] Question: Can you discuss the margin uplift from innovation gaining scale? - Management confirmed that margin accretion is expected as new products gain scale, with a focus on operational improvements and leveraging existing cost structures [90][92]

Core Viewpoint - Elanco Animal Health Incorporated appears to be turning a corner after years of market share losses and uneven execution, with a stabilized core business and promising innovation pipeline [1][2]. Business Performance - Investor meetings hosted by William Blair have led to an upgrade of Elanco's stock, highlighting the stabilization of the core business, which constitutes about 85% of sales, due to improved execution [2][3]. - The company's recent product launches in both livestock and pet health are expected to enhance growth, potentially contributing around five percentage points to overall growth in 2025 [4]. Product Pipeline and Innovation - Elanco's Zenrelia (ilunocitinib) received a positive opinion from the European Medicines Agency, with expectations for market approval and supply before the end of Q3 [5]. - New farm animal products like Bovaer and Experior, which currently face little to no competition, may increase demand for older products such as Rumensin [5]. Competitive Landscape - Elanco faces significant competition from larger, well-funded companies like Merck and Zoetis, which are also heavily investing in new product development [6]. - Merck's JAK inhibitor could impact the performance of Elanco's Zenrelia, as it is expected to have fewer safety concerns, while Zoetis has a strong track record of improving existing products [6]. Stock Performance - Elanco's stock is currently up 3.05%, trading at $14.18 [7].

Summary of Elanco Animal Health Conference Call Company Overview - **Company**: Elanco Animal Health - **CEO**: Jeff Simmons - **Event**: Stifel Jaws and Paws Conference 2025 Key Points Leadership Transition - Elanco announced a proactive leadership change with the departure of the CFO Todd, who has been with the company for over six years, to be succeeded by Bob Ben Hinbergen from Hillenbrand, emphasizing a cultural fit and value creation focus [2][4][6] Financial Performance - Elanco reported a solid first quarter with innovation revenue reaching **$198 million** and a **4% growth** in revenue, guiding for **4% to 6% growth** for the year [7][9][12] - The company has absorbed tariff impacts and earmarked **$25 million** of FX EBITDA tailwind for future potential pharma tariffs [7][12] - Cash debt paydown was raised from **$150 million** to between **$450 million and $500 million**, indicating strong cash flow management [12] Innovation and Growth - Elanco has seen **seven consecutive quarters of growth**, driven by innovation across its product portfolio, including products like Experior, Credelio, and AdTap [8][10][11] - The company is focusing on a basket of **six blockbusters** and additional products launched in the last three years to drive growth [11] - Credelio Quattro has captured **10% market share** shortly after launch, indicating strong market acceptance [29][30] Market Dynamics - The OTC business experienced a decline in January and February due to cold weather but rebounded in March and April, continuing into May [13][16] - Elanco's distribution strategy has expanded to include retailers like Tractor Supply and Target, enhancing accessibility for pet owners [16][17] Product Development - ZENRELIA is positioned for growth with a focus on changing language on labels to enhance vet adoption, with **11,000 vet clinics** currently using the product [41][42] - The company anticipates a significant market opportunity in the derm category, projected to exceed **$2 billion** [45] Margin Expansion Strategy - Elanco is implementing a company-wide margin expansion approach, focusing on gross-to-net pricing strategies and operational efficiencies [22][58][60] - The company expects to leverage new product launches for improved pricing realization in 2026 [62] Regulatory Environment - Elanco is advocating for streamlined regulatory processes and an exemption from pharma tariffs, emphasizing the unique nature of the animal health industry compared to pharmaceuticals [76][77][78] Future Outlook - The company is optimistic about the growth trajectory in both the pet and farm animal segments, with a focus on innovation and market expansion [70][72] - Elanco aims to solidify its position as a leader in the derm market and capitalize on the growing demand for animal protein [67][70] Additional Insights - The company is closely monitoring weather impacts on sales and is prepared to adjust strategies accordingly [16][17] - Elanco's approach to innovation is multi-faceted, focusing on both product differentiation and market penetration strategies [25][62] This summary encapsulates the key discussions and insights from the Elanco Animal Health conference call, highlighting the company's strategic direction, financial performance, and market opportunities.

Summary of Elanco Animal Health Conference Call Company Overview - **Company**: Elanco Animal Health - **Industry**: Animal Health Key Points and Arguments Financial Performance - Elanco reported a robust Q1 with a **4% constant currency revenue growth**, marking the **seventh consecutive quarter of growth** [4][5] - The company exceeded guidance on revenue, adjusted EBITDA, and adjusted EPS [5] - Revenue guidance was raised to **$660 million to $740 million** for the innovation basket initiated in 2021 [6] Innovation and Product Development - The innovation basket includes six key products contributing significantly to growth, particularly **Quattro**, **Experior**, and **ZENRELIA** [7][8] - **Experior** is identified as having a **$350 million potential market** in North America [8] - ZENRELIA is gaining traction with **11,000 clinics** adopting it, indicating strong market demand in the **$1.9 billion dermatology market** [25][26] - The derm market is expected to grow **double digits**, with ZENRELIA positioned as a leading product [25] Cash Flow and Debt Management - Elanco announced monetizing royalties on the Lotta Lanner asset, bringing in nearly **$300 million** for debt reduction [9] - The company anticipates **$450 million to $500 million** for debt paydown, improving leverage ratios [9] Tariff and Regulatory Environment - Elanco is actively managing tariff impacts, estimating a **$16 million to $20 million** effect primarily from U.S.-China trade relations [10][11] - The company is engaged in discussions with the administration regarding potential tariff exemptions for the animal health industry [16][19] - Regulatory reform discussions are ongoing, with a focus on streamlining processes with the FDA and USDA [17][34] Market Dynamics and Competitive Landscape - The farm animal segment is experiencing growth, with Elanco being a leader in beef, swine, and poultry [73] - The company is optimistic about the protein market, noting a **20% decline** in animal protein alternatives [74] - Elanco's competitive strategy includes leveraging its innovation pipeline and addressing market needs effectively [46][87] Future Outlook - Elanco is focused on expanding its product portfolio, with plans for **seven blockbuster products** in the pipeline [87] - The company is enhancing its distribution strategy, increasing physical availability across various retail channels [90][92] - The outlook for the farm animal segment remains positive, with specific growth anticipated in cattle and poultry, while the pig industry faces challenges [99] Additional Insights - Elanco emphasizes the importance of a stable core business supported by innovation, which is crucial for sustained growth [100] - The company is committed to maintaining a competitive edge through scientific rigor and addressing consumer demands for sustainability [80][81] Conclusion Elanco Animal Health is positioned for continued growth through innovation, effective management of market dynamics, and a strong focus on regulatory engagement. The company's diverse product portfolio and strategic initiatives in the animal health sector are expected to drive future performance.

Financial Data and Key Metrics Changes - Elanco reported revenue of $1,193 million, a decrease of 1% on a reported basis, but achieved organic constant currency growth of 4% compared to Q1 2024 [39][40] - Adjusted EBITDA was $276 million, a decrease of $18 million year-over-year, but increased by $8 million when excluding the impact of the Aqua divestiture and foreign exchange headwinds [44][45] - Adjusted EPS improved to $0.37, driven by a favorable discrete tax rate benefit and interest expense savings from debt reduction [45] Business Line Data and Key Metrics Changes - Total Pet Health revenue increased by 1% in constant currency, with U.S. Pet Health revenue declining by 3% due to a challenging retail environment and soft vaccine demand, while international Pet Health grew by 5% [40][41] - The U.S. Farm Animal business grew by 17%, driven by demand for Experior and the launch of Pradillac, while international Farm Animal business contributed 2% in organic constant currency [42][43] - Innovation revenue reached $198 million in Q1, leading to an increase in full-year expectations for innovation contributions to $660 million to $740 million [7][20] Market Data and Key Metrics Changes - U.S. Retail business declined by 21% in January and February due to adverse weather conditions, but rebounded to a positive 13% growth in March [14][16] - International Pet Health business saw 5% organic constant currency growth, driven by products like AdTab and Credelio [17][18] - The U.S. Farm Animal business experienced significant growth, particularly in cattle, with Experior leading the way [19][31] Company Strategy and Development Direction - Elanco's strategy focuses on innovation, cash management, and a global operating model to navigate external uncertainties [9][10] - The company is committed to maintaining a balanced profile of risks and implementing mitigating strategies to offset tariff impacts and macroeconomic challenges [11][12] - Continued investment in product launches and facility expansions is planned, with a focus on maintaining cost discipline [38] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's ability to deliver on 2025 goals, citing strong Q1 performance and positive trends in March and April [49][53] - The company is closely monitoring consumer spending and macroeconomic conditions, emphasizing its resilience and execution capabilities [104][106] - Management highlighted the growth potential in the animal protein market, indicating a favorable outlook for the farm animal business [106][107] Other Important Information - Elanco raised its full-year revenue guidance due to favorable foreign exchange impacts, maintaining an organic constant currency growth outlook of 4% to 6% [8][47] - The company expects to achieve a net leverage ratio of 3.9 to 4.3 times adjusted EBITDA by year-end, reflecting strong cash generation and debt reduction efforts [37][50] Q&A Session Summary Question: Can you elaborate on the Q2 guidance and the impact of investments on EBITDA? - Management confirmed that Q2 investments are aimed at supporting product launches during the peak parasiticide season, which may dampen near-term EBITDA but are expected to drive revenue growth in the second half [59][60] Question: What is the expected impact of tariffs and the pharma exemption on EBITDA? - Management indicated a potential $25 million EBITDA tailwind from foreign exchange moves, which has not been reflected in guidance due to uncertainty surrounding the pharma exemption [62][64] Question: Can you provide insights on the innovation revenue contributions? - Management highlighted that the overall innovation portfolio, including products like ZENRELIA and Credelio Quattro, is driving growth, with a focus on expanding market share and clinic adoption [71][93] Question: How is the macro environment affecting consumer spending? - Management noted that while monitoring consumer spending is essential, the company is well-positioned to navigate fluctuations due to its diverse product offerings and strong execution capabilities [104][106]

Financial Data and Key Metrics Changes - Elanco reported revenue of $1,193 million for Q1 2025, a decrease of 1% on a reported basis, but achieved 4% organic constant currency growth compared to Q1 2024 [39][40] - Adjusted EBITDA was $276 million, a decrease of $18 million year-over-year, but increased by $8 million when excluding the impact of the Aqua divestiture and foreign exchange headwinds [44][45] - Adjusted EPS improved to $0.37, reflecting a favorable discrete tax rate benefit and interest expense savings from debt reduction [45] Business Line Data and Key Metrics Changes - Total Pet Health revenue increased by 1% in constant currency, with U.S. Pet Health revenue declining by 3% due to a challenging retail environment and soft vaccine demand, while international Pet Health grew by 5% [40][41] - The U.S. Farm Animal business grew by 17%, driven by strong demand for Experior and the launch of Pradillac, while international farm animal revenue increased by 2% [42][43] - Innovation revenue reached $198 million in Q1, leading to an increase in full-year expectations for innovation contributions to $660 million to $740 million [6][18] Market Data and Key Metrics Changes - U.S. retail experienced a decline of 21% in January and February due to adverse weather, but rebounded to a positive 13% growth in March [13][16] - International Pet Health growth was driven by products like AdTab, Credelio, and Seresto, with AdTab doubling its revenue year-over-year [16][41] - The U.S. Farm Animal business saw significant growth, particularly in cattle, with Experior leading the way [17][31] Company Strategy and Development Direction - Elanco's strategy focuses on innovation, cash management, and a global operating model to navigate external uncertainties [7][10] - The company is committed to maintaining a balanced profile of risks and implementing mitigating strategies against tariffs and macroeconomic challenges [10][11] - Continued investment in product launches and facility expansions is planned, with a focus on long-term value creation [38] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving 2025 goals, citing strong Q1 performance and positive trends in March and April [48][52] - The company is prepared to address potential economic slowdowns and tariff impacts while leveraging favorable foreign exchange rates [11][48] - Management emphasized the importance of innovation and a diverse product portfolio in driving growth [34][35] Other Important Information - Elanco announced the monetization of its Lotta Lantern U.S. royalties for $295 million, which will aid in deleveraging efforts [37] - The company expects to maintain its full-year adjusted EBITDA and adjusted EPS guidance despite external challenges [10][48] Q&A Session Summary Question: Can you elaborate on the Q2 guidance and the impact of investments on EBITDA? - Management confirmed that Q2 investments are aimed at supporting product launches during the peak parasiticide season, which may dampen near-term EBITDA but are expected to drive revenue growth in the second half [57][59] Question: What is the expected impact of tariffs on EBITDA? - Management indicated a potential $25 million EBITDA tailwind from favorable foreign exchange rates, which has not been reflected in the current guidance due to uncertainties surrounding the pharma exemption [60][62] Question: Can you provide more details on the ZENRELIA label change? - Management confirmed ongoing constructive dialogue with the FDA regarding label changes, with expectations for feedback in the second half of the year [63][64] Question: What are the key drivers of innovation revenue growth? - Management highlighted the strong performance of the innovation portfolio, particularly ZENRELIA and Credelio Quattro, as significant contributors to the increase in innovation revenue expectations [70][92] Question: How is the macro environment affecting consumer spending? - Management noted that while monitoring consumer spending is essential, Elanco's diversified capabilities and innovation position the company well to navigate potential economic fluctuations [103][106]

Financial Performance & Guidance - Elanco's Q1 2025 revenue exceeded guidance by $25 million[9] - Adjusted EBITDA for Q1 2025 exceeded guidance by $26 million[9] - Adjusted EPS for Q1 2025 exceeded guidance by $005[9] - The company is raising its 2025 revenue guidance due to foreign exchange tailwinds, while maintaining adjusted EBITDA guidance of $830-$870 million and adjusted EPS guidance of $080-$086[11] - Elanco expects $450-$500 million of gross debt paydown in 2025[10] Revenue Analysis - Elanco achieved 4% organic constant currency revenue growth in Q1 2025[10, 14] - Q1 2025 total Elanco revenue was $1193 million, a decrease of 1% compared to $1205 million in Q1 2024[29, 31] - US Farm Animal revenue increased by 17% to $230 million in Q1 2025 compared to $197 million in Q1 2024[31] - International Farm Animal revenue decreased by 12% to $316 million in Q1 2025 compared to $360 million in Q1 2024, but increased 2% on an organic constant currency basis[31] Innovation & Portfolio - Q1 2025 innovation revenue contribution was $198 million[10, 18] - Elanco is raising its 2025 innovation sales target to $660-$740 million[10, 17, 20]

Financial Data and Key Metrics Changes - Fourth quarter revenue was $1.02 billion, representing a 1% reported decline, but organic constant currency growth was 4% [46] - Adjusted EBITDA for the fourth quarter was $177 million, an increase of $12 million on a reported basis [54] - Full year adjusted EPS came in at $0.91 compared to $0.89 in 2023, reflecting a year-over-year growth [58] Business Line Data and Key Metrics Changes - Total Pet Health revenue increased 6% in constant currency in the fourth quarter, with U.S. Pet Health growing 2% and international Pet Health growing 11% [47][48] - U.S. Farm Animal business achieved $223 million in sales, a 6% increase, driven by cattle market expansion [49] - International Farm Animal revenue was flat, impacted by the Kexxtone recall and strategic changes in certain geographies [50] Market Data and Key Metrics Changes - The U.S. dermatology market is projected to surpass $2 billion, with Zenrelia capturing significant market share [80] - The global carbon market for Bovaer is estimated to be $2 billion, with strong demand from farmers [38] - The U.S. dairy farmers earned approximately $10 million in credits from using Rumensin in the fourth quarter [39] Company Strategy and Development Direction - The company is focused on growth, innovation, and cash generation, with expectations for 2025 organic constant currency revenue growth of 4% to 6% [12][73] - Strategic divestiture of the aqua business has allowed for debt reduction and increased investments in product launches [10][20] - The company aims to leverage its comprehensive portfolio to enhance market share in both Pet Health and Farm Animal sectors [22][24] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in accelerating fundamentals for 2025, despite challenges from foreign exchange impacts [14][72] - The company anticipates continued growth from innovation and a stabilization of its base business [13][42] - Management highlighted the importance of effective commercial execution and the positive reception of new product launches [72] Other Important Information - The company achieved a net leverage ratio of 4.3 times at the end of the year, down from 5.6 times at the start of 2024 [20] - The company launched five new U.S. product approvals in 2024, contributing to a robust innovation pipeline [28] - The company expects adjusted EBITDA for 2025 to be between $830 million and $870 million, factoring in foreign exchange headwinds [64] Q&A Session Summary Question: What is the expected penetration of Zenrelia by year-end 2025? - Management indicated that Zenrelia is experiencing strong adoption, with a focus on increasing clinic penetration through aggressive sampling and direct-to-consumer efforts [81][84] Question: What factors contribute to the accelerating revenue growth in Q1 2025? - Management noted that the growth is driven by the ramp-up of Zenrelia and Credelio Quattro, alongside the absence of headwinds faced in the previous year [88][89] Question: What gives confidence in the innovation contribution for 2025? - Management highlighted strong momentum from products like Experior and AdTab, as well as the growth potential in the dermatology market with Zenrelia and Quattro [96][97] Question: How is the early launch of Credelio Quattro performing? - Management reported positive initial momentum, with strong veterinarian interest and a comprehensive commercialization strategy in place [115][116] Question: What are the dynamics behind the surge in Galliprant sales? - Management attributed the surge to its strong safety profile and effective marketing strategies, expecting continued performance into 2025 [120] Question: How does the company view the competitive environment in dermatology? - Management acknowledged competition as a headwind but emphasized the growing market and unmet needs that present opportunities for growth [125][126]