GPC3 ADC MRG006A
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乐普生物-B(02157):EGFRADC获批上市值得期待,多个管线产品快速推进中
Guotou Securities· 2025-08-27 13:47
Investment Rating - The report assigns a "Buy-A" investment rating to the company, with a 6-month target price of HKD 11.92 [4]. Core Insights - The company reported a revenue of HKD 466 million and a net profit of HKD 42 million for the first half of 2025. The approval of EGFR ADC is highly anticipated, with multiple pipeline products advancing rapidly [1][2]. - The company expects to disclose significant data at the ESMO 2025 conference, including Phase II data for MRG003 in combination with PD-1 for head and neck cancer and nasopharyngeal cancer [1]. - Revenue projections for 2025 to 2027 are estimated at HKD 750 million, HKD 880 million, and HKD 1.79 billion, respectively, with net profits expected to be HKD -80 million, HKD 10 million, and HKD 290 million [2]. Financial Performance - The company achieved a revenue of HKD 225.35 million in 2023, with projections of HKD 367.79 million for 2024 and HKD 748.58 million for 2025 [6][11]. - The net profit for 2023 was HKD -30.30 million, with expectations of HKD -87.90 million in 2025 and a turnaround to HKD 329.31 million by 2027 [11][12]. - The gross margin is projected to improve from 87.45% in 2023 to 88% in 2027, indicating a positive trend in profitability [12]. Pipeline and Collaborations - The company has several products in its pipeline, including TF ADC MRG004A, which has entered Phase III clinical trials, and CG0070, which has completed Phase I enrollment in China [2]. - The company has established multiple external licensing collaborations, including the licensing of CDH17 ADC MRG007 and two TCE-related IP assets [2]. Market Performance - The stock price as of August 26, 2025, was HKD 9.41, with a 12-month price range of HKD 2.27 to HKD 10.18 [4]. - The company has shown significant stock performance, with a 12-month absolute return of 282.5% [5].