Key Takeaways Galafold raked in $371.5M in the first nine months of 2025, accounting for over 80% of FOLD's product sales.Galafold benefits from broad global approvals and U.S. patent protection extending through 2038.FOLD's Pombiliti Opfolda delivered $77.5M sales in the first nine months of 2025, up 61% Y/Y.Amicus Therapeutics (FOLD) has made solid progress with its lead marketed product, Galafold (migalastat), which generates the majority of the company’s revenues.Galafold is approved for treating Fabry ...

Core Insights - BioMarin Pharmaceutical Inc. has acquired Amicus Therapeutics for $4.8 billion to enhance its market position in the rare genetic diseases sector against competitors like Alexion Pharmaceuticals and Vertex Pharmaceuticals [1][4] Acquisition Details - The acquisition involves purchasing all outstanding shares of Amicus at $14.50 per share, representing a 33% premium over its previous closing price [5] - The deal is financed through BioMarin's cash reserves and $3.7 billion in non-convertible debt, strategically avoiding equity dilution [2][6] - The acquisition is expected to close in the second quarter of 2026 and will add Amicus' therapies, Galafold and Pombiliti-Opfolda, which generated $449 million in sales in the first nine months of 2025, to BioMarin's portfolio [5][6] Market Reaction - Following the acquisition announcement, BioMarin's stock surged by 18%, while Amicus' stock increased by 30%, indicating strong investor confidence in the strategic benefits of the acquisition [2][7] - Joon Lee from Truist Financial set a price target of $100 for BioMarin, suggesting a potential upside of 68.7% from its trading price of $59.28 at the time of the announcement [4]

On Friday, BioMarin Pharmaceutical Inc. (NASDAQ:BMRN) agreed to acquire Amicus Therapeutics, Inc. (NASDAQ:FOLD) for a total equity value of about $4.8 billion."Immediately upon close, this transaction is expected to accelerate BioMarin's revenue growth and strengthen our financial outlook, delivering significant value to patients, employees, and stockholders. The transaction is expected to be accretive to Non-GAAP Diluted EPS in the first 12 months following close," said Alexander Hardy, President and Chief ...

We recently compiled a list of the 7 Most Promising Gene Editing Stocks According to Analysts. BioMarin Pharmaceuticals Inc. stands second among the most promising stocks. TheFly reported on December 19 that BMRN announced it will acquire Amicus Therapeutics in an all‑cash transaction valued at approximately $4.8 billion, paying $14.50 per share. The deal strengthens BMRN’s position in rare metabolic diseases by adding Amicus’s two marketed therapies: Galafold for Fabry disease and the Pombiliti + Opfolda ...

Key Takeaways BMRN will acquire all FOLD shares for $14.50 in cash, valuing the deal at $4.8B.The deal adds Galafold and Pombiliti-Opfolda, which added $449M in sales in the first nine months of 2025.BMRN will also gain U.S. rights to a late-stage drug DMX-200 being developed for a rare kidney disease.BioMarin Pharmaceutical (BMRN) announced that it entered a definitive agreement to acquire all outstanding shares of Amicus Therapeutics (FOLD) for $14.50 per share in cash, totaling $4.8 billion.The deal, app ...

BioMarin (BMRN) shares closed roughly 20% higher on Dec. 19 after announcing a $4.8 billion acquisition of Philadelphia-headquartered Amicus Therapeutics (FOLD). The all-cash transaction values each FOLD share at $14.50, a 33% premium over their previous close, indicating BioMarin’s commitment to expanding its footprint in the rare disease market. More News from Barchart Despite the recent rally, BioMarin stock is down some 18% versus its year-to-date high set in late March. www.barchart.com Signific ...

Core Viewpoint - BioMarin Pharmaceutical Inc. has successfully acquired Amicus Therapeutics for nearly $5 billion, which is expected to enhance its commercial portfolio and revenue growth significantly. Group 1: Acquisition Details - BioMarin entered into a definitive agreement to acquire Amicus Therapeutics for $14.50 per share, representing a 33% premium over Amicus's closing price on December 18 [2] - The acquisition will be funded through cash on hand and approximately $3.7 billion of non-convertible debt financing [3] Group 2: Financial Impact - The acquisition is anticipated to support BioMarin's long-term compound annual growth rate (CAGR) through 2030, with the two new treatments generating combined net product revenues of $599 million in the past year [4] - The transaction is expected to accelerate revenue growth and strengthen BioMarin's financial outlook, being accretive to Non-GAAP Diluted EPS within the first 12 months post-closure [5] Group 3: Market Performance - Following the announcement of the acquisition, BioMarin's stock surged 17.71% to close at $61.15, marking its third consecutive day of gains [1]

Summary of BioMarin Pharmaceutical's Acquisition of Amicus Therapeutics Conference Call Company and Industry - **Company**: BioMarin Pharmaceutical (NasdaqGS: BMRN) - **Acquisition Target**: Amicus Therapeutics - **Industry**: Rare diseases and biopharmaceuticals Core Points and Arguments 1. **Strategic Fit**: The acquisition of Amicus Therapeutics is seen as an exceptional strategic fit for BioMarin, enhancing its position in the rare diseases market with innovative therapies like Galafold and POMOP [4][6][17] 2. **Immediate Revenue Growth**: The deal is expected to accelerate BioMarin's revenue growth immediately upon closing, with both Galafold and POMOP projected to reach peak sales of $1 billion each [5][21][53] 3. **Financial Outlook**: The transaction is anticipated to be accretive to non-GAAP diluted EPS within the first 12 months and substantially accretive starting in 2027. The combined company is expected to generate additional cash flow, allowing for continued investment in innovation [5][8][14][76] 4. **Transaction Details**: BioMarin will acquire Amicus for $14.50 per share, valuing the deal at $4.8 billion, financed through cash and approximately $3.7 billion of non-convertible debt [7][8] 5. **Market Expansion Opportunities**: There are significant opportunities for expanding the reach of Galafold and POMOP in existing and new markets, with a focus on increasing diagnosis and treatment rates for underdiagnosed conditions like Fabry and Pompe diseases [11][24][73] Additional Important Content 1. **Intellectual Property Settlements**: Amicus has settled ongoing litigation related to Galafold's IP, preventing competitors from entering the U.S. market before 2037, which supports the growth outlook for Galafold [12][69] 2. **Underdiagnosed Conditions**: Both Fabry and Pompe diseases are considered underdiagnosed, with estimates suggesting a higher prevalence than currently diagnosed patients. This presents a significant opportunity for BioMarin to increase market penetration [23][24] 3. **Synergies and Integration**: The integration of Amicus is expected to yield operational synergies, leveraging BioMarin's scale to enhance the growth of both products. The focus will be on maintaining Amicus's capabilities while integrating operations [9][36][58] 4. **Long-term Growth Potential**: The combined business is projected to grow at a higher rate through the rest of the decade, with both products expected to contribute significantly to revenues by 2027 [39][53] 5. **Competitive Landscape**: BioMarin aims to differentiate Galafold and POMOP from existing therapies through unique mechanisms and real-world evidence supporting their efficacy, particularly in driving patient switches from traditional enzyme replacement therapies [42][54] This summary encapsulates the key points discussed during the conference call regarding BioMarin's acquisition of Amicus Therapeutics, highlighting the strategic, financial, and operational implications of the deal.

Acquisition Overview - BioMarin will acquire Amicus Therapeutics in an all-cash transaction for $14.50 per share, valuing Amicus' equity at approximately $4.8 billion[14] - The purchase price represents a 33% premium to Amicus' closing stock price on December 18, 2025[14] - The transaction is expected to close in Q2 2026, subject to regulatory clearance and approval by Amicus' stockholders[14] Financial Impact - The acquisition is expected to increase BioMarin's long-term revenue CAGR through 2030 and beyond[12] - It is anticipated to be accretive to Non-GAAP Diluted Earnings Per Share (EPS) in the first 12 months after close and substantially accretive beginning in 2027[12, 28] - BioMarin is committed to deleveraging, targeting gross leverage < 2.5x within two years after close[12, 28] - The transaction will be financed through a combination of cash on hand and approximately $3.7 billion of non-convertible debt financing[14] Strategic Rationale - The acquisition expands BioMarin's position as a leader in rare diseases by adding two marketed, high-growth products[4, 12, 28] - BioMarin's global scale and manufacturing capabilities will enable more patients to benefit from Galafold and Pombiliti + Opfolda[12, 28] - The deal diversifies BioMarin's revenue mix and strengthens its commercial portfolio[5, 12, 15] Product Portfolio - Galafold, an oral therapy for Fabry disease, is projected to generate $458 million in revenue in FY'25, with a growth rate of +10-15%[19] - Pombiliti + Opfolda, a two-component therapy for Pompe disease, is projected to generate $70 million in revenue in FY'25, with a growth rate of +50-65%[24]

This story was originally published on BioPharma Dive. To receive daily news and insights, subscribe to our free daily BioPharma Dive newsletter. BioMarin Pharmaceutical has agreed to buy Amicus Therapeutics in a $4.8 billion deal that would hand it two marketed drugs for rare diseases and a third asset in late-stage human testing. The all-cash acquisition, announced Friday, has BioMarin paying $14.50 for each Amicus share, or a 33% premium to the latter’s closing stock price on Thursday. The deal has u ...