Core Insights - A research team led by Fang Ying from Beijing Brain Science and Brain-like Research Institute has developed a new type of high-throughput, stretchable flexible electrode that addresses the challenges of traditional flexible electrodes in brain-machine interface (BMI) technology, particularly in dynamic brain movements [1][2][3] - The new stretchable electrode architecture can dynamically follow brain movements with a required stretching force that is only 1/100th of that needed for Neuralink's linear electrodes, significantly reducing mechanical damage to brain tissue and minimizing immune responses [2][3] Group 1 - The new flexible electrode technology provides a foundational solution for the long-term stability of invasive brain-machine interfaces, overcoming issues of electrode displacement and inflammation caused by brain tissue movement [2][3] - Research conducted on macaques demonstrated that the stretchable flexible electrode could achieve long-term stable recordings in the brain, successfully capturing 257 single-neuron signals with a 256-channel implant and high-quality neural signals with a 1024-channel implant [2][3] Group 2 - This innovative technology is expected to address key obstacles for the clinical application of invasive brain-machine interfaces in China, potentially allowing the country to gain a competitive edge in the global market [3] - The advancement in this technology is anticipated to enhance the performance of brain-machine interfaces, contributing to the overall development of the industry and improving public health through cutting-edge technology [3]

为解决这一困扰行业的难题，方英团队提出一种新型的高通量"可拉伸"电极架构，其不仅可动态跟随大 脑运动，且其拉伸所需力度仅为Neuralink线性电极的1/100，这意味着可拉伸柔性电极对脑组织的机械 损伤更低，可极大程度减少传统线性电极引发的免疫反应和胶质斑痕。 以猕猴为试验对象开展的研究结果表明，可拉伸柔性电极能够实现猕猴大脑中的长期稳定记录；在植入 256通道该电极后，团队成功采集到257个单神经元信号，并实现了对大脑运动意图的高精度解码。在植 入1024通道该电极后，团队捕获到大规模、高质量的神经元信号。 记者近日获悉，北京脑科学与类脑研究所资深研究员、智冉医疗创始人方英领衔的科研团队，成功研制 出一款兼具高通量信号采集与生物力学顺应性的可拉伸柔性电极。该研究成果解决了传统柔性电极在应 对大脑动态运动时易移位、易脱出的瓶颈问题，为侵入式脑机接口的长期稳定性提供了底层解决方案， 有望为我国侵入式脑机接口从实验室走向大规模临床应用解决关键障碍。该成果于2月5日发表于国际学 术期刊《自然·电子学》。 侵入式脑机接口技术被业界认为是高带宽人机交互的终极方向。马斯克创办的Neuralink公司于2024年初 完成 ...