Core Insights - China's first invasive brain-computer interface (BCI) clinical trial has been successfully conducted, making it the second country globally to enter this phase after the United States [1] - The trial involved a 37-year-old male subject who lost his limbs due to an electrical accident, and he was able to control a computer touchpad through thought after 2-3 weeks of training [1][2] - The developed flexible neural electrodes have a small cross-sectional area and high flexibility, reducing damage to brain tissue [1][2] Group 1 - The BCI device implanted has a diameter of 26mm and a thickness of less than 6mm, allowing for a minimally invasive surgical procedure [2] - The implantation process involves creating a small groove in the skull and inserting ultra-flexible neural electrodes into the brain tissue, taking only 20-30 minutes [2] - The electrodes are designed to collect neural signals accurately by being placed close to the brain's motor cortex [2][3] Group 2 - Precise positioning and implantation are critical for the success of the surgery, achieved through advanced imaging techniques [3] - The research team plans to enable the subject to control a robotic arm for physical tasks, expanding the application of the BCI technology [3]

Macro Dynamics - The number of registered individual businesses in China has reached 126 million, with new regulations facilitating their transformation into enterprises through a simplified registration process [1] Financial Institutions - French BPCE Group is set to acquire Portugal's fourth-largest bank, Novo Banco, for approximately €6.4 billion, marking the largest cross-border acquisition in the Eurozone in a decade [4] Market Data - U.S. stock indices closed down over 1%, with the Dow Jones falling 1.79%, the Nasdaq down 1.3%, and the S&P 500 decreasing by 1.13%. The energy sector saw significant gains, with Houston Energy rising over 119% [5] - International crude oil futures saw a substantial increase, with WTI crude oil rising by 7.26% to $72.98 per barrel, and Brent crude oil increasing by 7.02% to $74.23 per barrel [6] Company Dynamics - Pop Mart has temporarily suspended offline sales of LABUBU plush toys in South Korea due to potential safety concerns [7] - ROMOSS issued an apology regarding the ban of its power banks in multiple universities, committing to take responsibility for any defective products [8] - GAC Group announced a commitment to ensure the timely payment of dealer rebates to promote healthy development in the automotive industry [10] - Japan's Ministry of Land, Infrastructure, Transport and Tourism has mandated inspections of Boeing 787 aircraft following a crash incident involving an Indian airline [11]

Core Viewpoint - The successful initiation of China's first invasive brain-computer interface (BCI) clinical trial marks the country as the second globally, following the United States, to enter this stage of clinical testing [1] Group 1: Clinical Trial Details - The clinical trial is a collaboration between the Chinese Academy of Sciences and Fudan University, focusing on a 37-year-old male subject who lost his limbs due to an electrical accident [2] - The BCI device was implanted in March 2023, and the system has been stable without infections or electrode failures for over a month [2] - The subject can control a computer touchpad to play chess and racing games using thought alone, achieving a level comparable to that of a normal person after just 2-3 weeks of training [2] Group 2: Research and Development - A dedicated team for BCI research was established under the "14th Five-Year Plan," focusing on various aspects such as motor perception and neural function repair [3] - The developed flexible neural electrodes are significantly smaller and more flexible than those used by Neuralink, reducing damage to brain tissue [3][5] - The electrodes have demonstrated high-density, large-area, and long-term stable neural signal acquisition capabilities in various animal models [3] Group 3: Surgical Procedure - The implanted device is the smallest of its kind globally, measuring 26mm in diameter and less than 6mm in thickness, which is half the size of Neuralink's product [8] - The surgery involves a minimally invasive technique, taking about 20-30 minutes, and is performed using a high-precision navigation system [9][11] - Pre-surgical planning included creating a detailed 3D model of the subject's brain to ensure precise electrode placement [11] Group 4: Future Prospects - The project team plans to conduct additional clinical trials, with expectations to perform 3-4 more trials by 2025 and initiate multi-center trials by 2026 [11] - The BCI system aims to assist patients with complete spinal cord injuries and other conditions in controlling external devices to improve their quality of life [11] - Future developments may include enabling subjects to control robotic arms and other intelligent devices, expanding their functional capabilities [12]

Core Insights - The Chinese Academy of Sciences, in collaboration with Huashan Hospital affiliated with Fudan University and relevant enterprises, has successfully conducted China's first prospective clinical trial of an invasive brain-computer interface [1] - This achievement signifies that China has become the second country globally to enter the clinical trial phase for invasive brain-computer interface technology [1]