Core Viewpoint - UK BioBank emphasizes the importance of its database for global health and disease research, particularly in light of recent restrictions imposed by the NIH on data access for researchers in China and other countries [1][4][5]. Group 1: Impact of NIH Restrictions - The NIH has prohibited access to its controlled databases, including the SEER database, for researchers from specific countries, including China, effective April 4, 2025 [4][8]. - The SEER database is crucial for cancer research, covering data from 48% of the U.S. population, and has been relied upon by approximately 75% of cancer epidemiology papers published by Chinese scholars [9][10]. - The restrictions have raised concerns about a potential "cold war" in scientific research, with fears that other databases may follow suit in limiting access for Chinese researchers [5][10]. Group 2: Need for Domestic Data Sharing - Chinese research institutions must enhance their capabilities and promote scientific data sharing to avoid being significantly hindered by international restrictions [6][10]. - The current state of biomedical research in China shows a significant reliance on foreign databases, with 99% of pharmaceuticals and 100% of databases not being domestically sourced [13][14]. - Since 2004, China has made efforts to build national scientific data sharing platforms, but challenges remain in the implementation and effectiveness of these initiatives [15][17]. Group 3: Challenges in Data Sharing - There is a systemic lack of focus on scientific data development in China, with many efforts being limited to small teams rather than a cohesive national strategy [17][18]. - The reliance on foreign databases in educational institutions hampers the development of domestic data products, which, despite having competitive potential, struggle due to low user engagement [18][19]. - The phenomenon of "false sharing" is prevalent, where databases are claimed to be open but are not genuinely accessible, leading to a cycle of underutilization and slow development [21][22].

导读： 美国NCI维护的全球最大癌症数据库SEER已禁止中国用户访问，此前已经注册过的用户再也无法登录。另据悉，很快英国方面的 相关数据库也将禁止中国用户使用。 特别提示 微信公众号机制调整，请点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 当地时间 4 月 4 日，由美国国家癌症研究所（NCI，Na ti o n a l Ca n c e r I n stit u t e）维护的、全球最大、最权威的公开癌症 数据库之一 SEER（Su r v e ill a n c e， Ep i d emi o l o g y， a n d En d Re s u lts）数据库，已经禁止中国用户使用，此前已经注 册过的用户再也无法登录。另据悉，很快英国方面的相关数据库也将禁止中国用户使用。 S E E R 禁 止中国用户 登录的页面 显示 SEER 在一封回复给用户的邮件中表示："如果您最近失去了对 SEER*St a t 账户的访问权限，并且无法再登录，请留意最 近的政策变化，该变化要求美国国家癌症研究所删除对 SEER 数据的访问权限。目前，我们无法恢复您的账户访问权限 ...