博睿康 NeuroHUB助力国内首个剧场神经美学实验 近日，国内首个真实剧场环境下的神经美学实验在新清华学堂进行，八名佩戴便携式脑电设备的志愿者在 现场观看舞剧《咏春》，设备可同时采用无线方案同步记录数据，实时捕捉观众沉浸于艺术时的神经活 动。 无线自由：解放科研想象力 NeuroHUB采用模块化的便携可穿戴设计，采用无线方案同步传输数据，志愿者可自然落座剧场任意位置。 设备提前40分钟调试完成，演出全程无感佩戴，确保艺术体验的纯粹性。 群体超扫描：多人大脑实时对话 志愿者佩戴的设备是由博睿康自主研发的NeuroHUB多模态研究平台， 这也是首次实现真实场景下多人观演 脑电及生理信号的毫秒级精准同步采集记录 。当青绿山水在舞台流淌，当电波穿越时空帷幕，志愿者们的 大脑正掀起一场无声风暴。数据显示，当观众沉浸于演出时，大脑活跃度显著提升，这种全脑联动与情感 分布密切相关——这正是现场艺术直击人心的神经密码。 在这场颠覆传统的实验中，博睿康自主研发的NeuroHUB多模态平台展现出三大核心优势： NeuroHUB首创的便捷群体同步方案突破实验室单一场景的局限，支持10人以上脑电和生理信号毫秒级精准 对齐。 真实场 ...

Core Insights - The recent breakthrough in AI enzyme design by MoleculeMind and Hong Kong Polytechnic University has been recognized at the ICML 2025 conference, marking a significant advancement in the field of AI enzyme design [1] - The traditional methods of enzyme discovery and optimization are time-consuming and costly, with a success rate of less than 1%, highlighting the urgent need for innovative solutions in the biomanufacturing sector [2] - The introduction of the SENZ method, which utilizes substrate structure similarity for enzyme design, represents a novel approach that could revolutionize enzyme generation [3][5] Industry Overview - Enzymes are crucial for the development of the trillion-dollar bio-economy, impacting sectors such as biomedicine, green chemistry, and environmental degradation [1] - The lack of ideal biocatalysts is a major barrier to scaling production in the biomanufacturing industry, leading to annual capacity losses exceeding $100 billion in pharmaceuticals, chemicals, and agriculture [2] - AI protein design has emerged as a promising solution to generate precise catalysts by learning from existing enzyme structure-function relationships, although it faces challenges with novel synthetic molecules due to limited training data [2] Company Developments - MoleculeMind has developed the SENZ method, which integrates biological data retrieval and generative AI to create enzymes without direct catalytic data, thus addressing a critical challenge in enzyme generation [3][5] - The SENZ method has demonstrated superior performance compared to traditional enzyme design methods, potentially providing tailored solutions for complex drug synthesis and environmental remediation [6] - MoleculeMind is expanding its capabilities in "on-demand design" across various fields, including antibodies, vaccines, and industrial enzymes, aiming to provide innovative biological solutions for health, environmental, and sustainability challenges [7]

来源：ITALDESIGN 编 译 / 钱亚光 设 计 / 张 萌 来 源 / w w w. a u t o n e w s. c o m , w w w. c o r r i e r e . i t , w w w. c a r r o z z i e r i - i t a l i a n i . c o m 据意大利媒体报道，大众汽车集团旗下的奥迪品牌已将其意大利设计与工程公司 Italdesign公司挂 牌出售。此举是其大规模削减成本措施的一部分。这一举动引发了员工和行业观察人士的担忧，他 们对这家具有标志性意义的公司的未来表示担忧。 ↓这款楔形的莲花 Esprit 轿车是在 1975 年的巴黎车展上推出的，其设计者是吉奥吉托·乔治亚罗，他是意大利设计 公司 Italdesign 的联合创始人。 出售 Italdesign 的这一决定正值大众集团面临转型挑战之际。尽管电动汽车销量有所增长，但大众 集团首席执行官奥博姆（Oliver Blume）正推动整个集团进行成本削减措施的实施。因为欧洲市场 形势不佳，且来自中国汽车制造商的竞争日益激烈。 ↓ 最初的高尔夫由Italdesign打造 今年第一季度，奥 ...

Financial Performance - Net revenue increased by 8.9% on a constant-currency basis and 10.4% organically[15] - Cardiopulmonary revenue grew by 15.0%, driven by Essenz™ Perfusion system sales and consumables demand[12] - Neuromodulation revenue increased by 4.7%, with strength in Europe and Rest of World regions[12] - U S Epilepsy revenue grew 2.2%, partially impacted by procedure deferrals[12] - Adjusted diluted EPS was $0.88[12] - Adjusted free cash flow was $20 million[12] Guidance and Outlook - Full-year 2025 revenue guidance raised by 100 basis points to 6.0% - 7.0% on a constant-currency basis and 7.0% - 8.0% on an organic basis[10] - Full-year 2025 adjusted diluted earnings per share range revised to $3.60 - $3.70[10] - Adjusted operating income margin increase of > 190bps and adjusted operating income growth of > 15% is expected[45] - Targeting $135 - $155 million of adjusted free cash flow for full-year 2025[39] SNIA Environmental Liability - Recorded a liability of €333.3 million ($360.4 million as of March 31, 2025) related to SNIA environmental liability ruling[10]