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武汉创新药研发插上AI翅膀 国家一类新药获批数量居全国前列
Chang Jiang Ri Bao· 2025-11-14 01:02
Core Insights - AI-driven drug discovery is revolutionizing the pharmaceutical industry in Wuhan, significantly reducing costs and time for drug development [1][2][3][4][5][6] - The integration of AI technologies is enhancing the efficiency of drug synthesis and discovery processes, positioning Wuhan as a leader in innovative drug research [1][2][3][4][5][6] Group 1: AI in Drug Development - Traditional drug synthesis methods take hours, while AI-supported systems can complete the same tasks in minutes, reducing the cost of drug raw materials from tens of thousands to 3,000 yuan per kilogram [1] - AI technology has helped reduce drug research and development costs by nearly 40% at Renfu Pharmaceutical, with a 37.5% overall reduction in R&D expenses [2] - The AI-assisted drug discovery process can identify optimal drug candidates in as little as 12 months, compared to the traditional 2-3 years [2] Group 2: Innovations in Chemical Synthesis - Wuhan Zhihua Technology's ChemAIRS platform can design chemical synthesis routes in minutes, adhering to green chemistry principles and enhancing both economic and environmental efficiency [3] - The AI capabilities of Zhihua Technology are set to lower the barriers for non-experts to utilize these advanced tools, marking the advent of an "AI chemist" era [3] Group 3: Advancements in Synthetic Biology - Wuhan Lihua Intelligent Manufacturing has developed the world's largest synthetic biology reaction/pathway database, enabling rapid information retrieval and original pathway design in 14 to 20 days [4] - The AI-driven design platform has significantly reduced the cost of high-value raw materials from tens of thousands to 3,000 yuan per kilogram, while ensuring safer and more environmentally friendly production methods [4] Group 4: Ecosystem and Talent Development - The integration of AI and biomedicine in Wuhan is supported by a robust ecosystem, including platforms like Lihua Intelligent Manufacturing and Zhihua Technology, which streamline the drug development process [5][6] - Local universities are producing skilled professionals who understand both AI and pharmaceutical sciences, strengthening the talent pool for the AI pharmaceutical industry [6]