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赜灵生物冲刺港交所:结构生物学、AI及临床疾病模型驱动的小分子创新药企
IPO早知道· 2026-01-14 03:10
Core Viewpoint - Chengdu Zeling Biopharmaceutical Technology Co., Ltd. is preparing for an IPO on the Hong Kong Stock Exchange, focusing on innovative small molecule therapies for unmet medical needs in hematological diseases, oncology, CNS, and immune/inflammatory diseases [3][9]. Product Pipeline - As of January 5, 2026, Zeling Biopharmaceutical has established a pipeline consisting of eight proprietary assets, including two core products, FM and PM, which are in late-stage clinical trials [3][9]. - FM is a novel triple-target inhibitor for treating myeloproliferative neoplasms (MPN), showing a twofold increase in response rate compared to the standard treatment, ruxolitinib [5][6]. - PM is a high-selectivity HDAC inhibitor designed for relapsed/refractory DLBCL, demonstrating impressive clinical efficacy, particularly in subtypes with poor responses to current therapies [7]. Technological Platforms - The company's drug discovery capabilities are driven by three integrated technology platforms: ZeniFold for structural biology, ZeniMind for AI-driven drug discovery, and ZeniScreen for clinical-relevant disease model screening [8]. - These platforms enable a rational, data-driven, and efficient drug discovery process, addressing key limitations of existing therapies [8]. Financial Backing and IPO Plans - Zeling Biopharmaceutical has received investments from notable institutions, completing a C round financing of 511 million RMB in November 2025, with a post-money valuation of 3.411 billion RMB [8]. - The IPO proceeds will primarily fund the R&D of core products FM and PM, other pipeline assets, enhancement of technology platforms, and general corporate purposes [9].