Summary of China Healthcare & Pharmaceuticals 3Q25 Drug Sales Tracker Industry Overview - The report focuses on the **China healthcare and pharmaceuticals industry**, specifically analyzing drug sales data for the third quarter of 2025 (3Q25) [1][2]. Key Findings - **Overall Market Performance**: The overall drug market sales in China declined by **6.2% year-on-year (y-y)** but increased by **6% quarter-on-quarter (q-q)**, totaling **CNY 226 billion** in 3Q25 [2][1]. - **Performance of Domestic Pharma Companies**: - **Hengrui**: Sales decreased by **0.1% y-y** to **CNY 5.8 billion**. - **Sinobio**: Sales fell by **0.9% y-y** to **CNY 4.1 billion**. - **Hansoh**: Sales declined by **0.8% y-y** to **CNY 2.0 billion**. - **Qilu Pharma**: Experienced a **9% y-y decline** to **CNY 4.7 billion**. - **CSPC**: Sales dropped by **17% y-y** to **CNY 3.6 billion** [4][4]. - **Biotech Companies' Growth**: - **BeOne**: Sales increased by **20.4% y-y** to **CNY 1.5 billion**. - **Innovent**: Sales rose by **24.6% y-y** to **CNY 1.5 billion**. - **Akeso**: Notable growth of **130.1% y-y** to **CNY 156 million**. - **Remegen**: Sales grew by **54.2% y-y** to **CNY 255 million** [5][5]. - **Multinational Corporations (MNCs) Performance**: - **AstraZeneca**: Sales decreased by **4.9% y-y** to **CNY 6.1 billion**. - **Novartis**: Sales fell by **7.3% y-y**. - **Roche**: Sales declined by **13.6% y-y**. - **Pfizer**: Sales dropped by **13.9% y-y** [6][6]. - **Notable Growth in Specific Products**: - **Novo Nordisk**: Sales increased by **22.3% y-y** to **CNY 3.7 billion**, driven by **Semaglutide** sales growth of **35% y-y** to **CNY 1.3 billion**. - **Eli Lilly**: Sales of **Tirzepatide** reached **CNY 2 million** in 3Q25 [7][7]. Additional Insights - **Hengrui's Specific Products**: - **Camrelizumab**: Sales rose by **34% y-y** to **CNY 445 million**. - **Pyrotinib**: Sales remained flat at **CNY 280 million**. - **Mecapegfilgrastim**: Sales increased by **4% y-y** to **CNY 435 million** [9][9]. - **Sinobio's Product Performance**: - **Anlotinib**: Sales grew by **6% y-y** to **CNY 646 million**. - **Magnesium Isoglycyrrhizinate**: Sales increased by **7% y-y** to **CNY 682 million** [9][9]. - **CSPC's Oncology Drugs**: - **Duomeisu**: Sales surged by **91% y-y** to **CNY 40 million**. - **Jinyouli**: Sales declined by **19% y-y** to **CNY 609 million** [10][10]. - **Hansoh's Oncology Drugs**: - **Almonertinib**: Sales rose by **14% y-y** to **CNY 560 million**. - **Flumatinib**: Sales increased by **25% y-y** to **CNY 185 million** [10][10]. Conclusion - The China healthcare and pharmaceuticals market is experiencing mixed results, with domestic companies facing declines while biotech firms show significant growth. MNCs are also struggling, indicating a challenging environment for the industry overall. The data suggests potential investment opportunities in biotech companies that are outperforming their peers.

Summary of Hualan Biological Engineering (002007.SZ) Earnings Review Company Overview - **Company**: Hualan Biological Engineering - **Ticker**: 002007.SZ - **Industry**: Plasma products and vaccines Key Financial Results - **1H25 Revenue**: Rmb1,798 million, an increase of 9% year-over-year (yoy) [1] - **1H25 Net Profit**: Rmb516 million, an increase of 17% yoy [1] - **Product Revenue Breakdown**: - Albumin: Rmb696 million (+8% yoy) - IVIG: Rmb453 million (-1% yoy) - Other Plasma Products: Rmb588 million (+15% yoy) - Vaccines: Rmb57 million (+93% yoy) [1] Market Dynamics - **Price Decline**: Unit prices for albumin and IVIG declined by approximately 5% [1] - **Competitive Landscape**: Despite price declines, Hualan's performance is considered favorable compared to industry peers, with no inventory pressure reported [1] Regulatory Developments - **Recombinant Albumin Approval**: China's first recombinant albumin was approved on July 18, 2025. However, Hualan management believes the near-term impact on plasma-derived albumin will be minimal due to limited indications [2] - **Long-term Outlook**: Hualan expects human plasma albumin to maintain its usage habits and cost advantages, mitigating concerns about recombinant albumin's threat to the industry [2] Growth Drivers - **Plasma Collection Stations**: Hualan is expanding its raw material supply through the ramp-up of seven nearly-approved plasma collection stations, which are expected to drive growth in plasma products [4] - **Biosimilar Approval**: Hualan Gene, in which Hualan holds a 40% stake, received approval for a bevacizumab biosimilar, generating Rmb58.9 million in revenue for 1H25, although this will not be consolidated into Hualan's financial statements [3] Investment Outlook - **Rating**: The company is rated as a "Buy" with a target price of Rmb19, indicating an upside potential of 8% from the current price of Rmb17.60 [11] - **Valuation Methodology**: The target price is based on a 5-year exit P/E of 18.1x applied to 2025E EPS, referencing a global peer P/E of 19x and a 5-year earnings CAGR of 10% [10] - **Risks**: Key risks include stricter controls on albumin prescriptions, regulatory restrictions affecting IVIG pricing, rising accounts receivable days leading to asset impairments, and intensified competition in the flu vaccine market [10] Revised Estimates - **Revenue Estimates**: Slight revisions made to revenue estimates for 2025E (Rmb4,843 million), 2026E (Rmb5,257 million), and 2027E (Rmb5,589 million), reflecting a decrease of 4.5%, 4.8%, and 5.0% respectively [8] Conclusion - Hualan Biological Engineering is positioned for growth in the plasma products sector, supported by regulatory approvals and expansion of collection capabilities. The company maintains a positive long-term outlook despite competitive pressures and pricing challenges.