Core Insights - ClearBridge Investments reported that mid-cap stocks experienced growth in Q3 2025, driven by a favorable monetary policy environment and stabilizing earnings [1] - The Federal Reserve's rate cuts positively impacted small and mid-cap stocks, with value stocks outperforming growth stocks [1] - The ClearBridge Mid Cap Strategy outperformed the Russell Midcap Index, primarily due to stock selection in the consumer staples and healthcare sectors [1] Company-Specific Insights - Bio-Techne Corporation (NASDAQ:TECH) has a market capitalization of $9.57 billion and focuses on life science reagents, instruments, and services [2] - The stock of Bio-Techne Corporation saw a one-month return of -0.32% and a 52-week decline of 15.36%, closing at $61.40 on November 12, 2025 [2] - ClearBridge initiated a new position in Bio-Techne, citing its high-margin consumables and instrumentation portfolio as key factors for its appeal as a growth-oriented investment [3] Financial Performance - In Q1 2026, Bio-Techne Corporation reported revenues of $286.6 million, reflecting a 1% year-over-year decline on both an organic and reported basis [4] - Despite the potential of Bio-Techne as an investment, the company is not among the most popular stocks among hedge funds, with 37 hedge fund portfolios holding its stock at the end of Q2 2025 [4]

Company Overview - Ralliant has approximately 7,000 team members and 21 manufacturing sites[19] - The company serves around 90,000 customers[19] - Ralliant's revenue is over $2 billion[19] - The company possesses around 2,200 active patents[19] Financial Targets - The company targets revenue growth of 3-5% through the cycle[19, 37] - Adjusted EBITDA margin target is in the low to mid-20s percentage range[19, 37] - Free cash flow (FCF) conversion target is above 95%[19] - Net leverage target is 1.5x – 2.0x[19] - The company aims to generate over $1 billion of cumulative FCF through 2028[37] Revenue Breakdown by Segment - Test & Measurement segment accounts for approximately 60% of revenue[19, 22] - Sensors & Safety Systems segment accounts for approximately 40% of revenue[19, 22] Revenue Breakdown by End Market - Diversified Electronics represents 22% of revenue[19, 23] - Industrial Manufacturing represents 19% of revenue[19, 23] - Defense & Space represents 16% of revenue[19, 23] - Utilities represents 13% of revenue[19, 23] - Communications represents 13% of revenue[19, 23] - Semiconductor represents 9% of revenue[19, 23] - Other (including Food and Beverage, Healthcare, and HVAC) represents 9% of revenue[19, 23, 24]

Core Insights - 10x Genomics reported Q3 CY2025 results that exceeded Wall Street's revenue expectations, with sales of $149 million, reflecting a 1.7% year-on-year decline [1][7] - The company provided a positive revenue guidance for Q4 CY2025 at $156 million, which is 3.5% above analyst expectations [1][7] - The GAAP loss per share was $0.22, which was 22.3% better than analysts' consensus estimates of $0.28 [1][7] Company Overview - Founded in 2012, 10x Genomics develops instruments, consumables, and software for analyzing biological systems at single-cell resolution and spatial context [4] Revenue Growth - Over the last five years, 10x Genomics achieved a compounded annual growth rate of 19.6% in sales, outperforming the average healthcare company [5] - However, the company's annualized revenue growth over the last two years was only 4.2%, indicating a slowdown compared to its five-year trend [6] Quarterly Performance - The revenue for Q3 CY2025 was $149 million, surpassing analyst estimates of $142.4 million by 4.6% [7] - The operating margin improved to -21.6%, up from -27.4% in the same quarter last year [7] - The company anticipates a 5.5% year-on-year decline in sales for the next quarter [9] Segment Analysis - The Consumables segment, which represents recurring orders, has shown flat revenue growth over the last two years, lagging behind the overall sales performance of the company [8]

Company Overview - Bio-Techne Corporation (TECH) is headquartered in Minneapolis, Minnesota, and specializes in developing, manufacturing, and selling life science reagents, instruments, and services for research, diagnostics, and bioprocessing markets, with a market cap of $9.3 billion [1] Earnings Expectations - Analysts expect TECH to report a profit of $0.37 per share on a diluted basis for the fiscal first quarter of 2026, which is unchanged from the same quarter last year [2] - For the full fiscal year, analysts project an EPS of $1.76, reflecting a 2.9% increase from $1.71 in fiscal 2025, and an expected rise to $2 in fiscal 2027, representing a 13.6% year-over-year growth [3] Stock Performance - TECH stock has underperformed the S&P 500 Index, which gained 14.4% over the past 52 weeks, with TECH shares down 18.7% during the same period [4] - The stock also underperformed the Health Care Select Sector SPDR Fund, which saw a 7.8% loss in the same timeframe [4] Recent Financial Results - On August 6, TECH reported its Q4 results, with an adjusted EPS of $0.53, surpassing Wall Street expectations of $0.50, and revenue of $317 million, exceeding forecasts of $315.4 million [5] Analyst Ratings - The consensus opinion on TECH stock is bullish, with a "Strong Buy" rating overall; out of 16 analysts, 11 recommend "Strong Buy," one suggests "Moderate Buy," and four give a "Hold" rating [6] - The average analyst price target for TECH is $66.77, indicating a potential upside of 11.9% from current levels [6]

Core Viewpoint - MKS Inc. is set to release its third quarter 2025 financial results on November 5, 2025, with a subsequent conference call scheduled for November 6, 2025, at 8:30 a.m. Eastern Time [1] Company Overview - MKS Inc. is a global provider of enabling technologies that transform various industries, particularly in semiconductor manufacturing, electronics, and specialty industrial applications [2] - The company offers foundational technology solutions, including instruments, subsystems, systems, process control solutions, and specialty chemicals technology, aimed at improving process performance and optimizing productivity [2] - MKS's solutions address challenges related to miniaturization and complexity in advanced device manufacturing, enhancing power, speed, features, and connectivity [2]

Core Insights - Becton, Dickinson and Co. (BDX) is a multinational medical technology company focused on manufacturing and selling medical devices, instruments, and reagents globally [1] Financial Performance - The company is set to report its Q4 2025 earnings on November 6, with analysts expecting an EPS of $3.92, an increase from $3.81 in the prior year [2] - Quarterly revenue is anticipated to reach $5.92 billion, up from $5.44 billion a year earlier [2] - In Q3 2025, Becton Dickinson reported an adjusted EPS of $3.68, exceeding the consensus estimate of $3.41, and revenues of $5.51 billion, slightly above the consensus of $5.49 billion [3] Growth and Strategic Initiatives - The CEO highlighted an increase in organic growth trajectory in Q3, along with strong margin and EPS growth, which led to a raised EPS guidance for the full year [4] - The full-year 2025 adjusted EPS guidance has been raised to a range of $14.30 to $14.45, reflecting a $0.18 increase and a 9.4% growth at the midpoint [4] - An agreement was announced to combine BD's Biosciences and Diagnostic Solutions business with Waters Corporation, aimed at creating a leader in life sciences and diagnostics focused on high-volume testing [4]

Group 1 - Mairs & Power Balanced Fund reported a return of 2.66% in the first half of 2025, underperforming benchmark indexes which rose 5.43% and 5.67% respectively [1] - The fund's performance was impacted by external factors such as tariff uncertainty, conflicts in the Middle East, and rising national debt [1] - The fund experienced a recovery, rising 25% from its low at the beginning of the quarter [1] Group 2 - Bio-Techne Corporation (NASDAQ:TECH) has a market capitalization of $8.239 billion and focuses on life science reagents, instruments, and services [2] - The stock of Bio-Techne Corporation saw a one-month return of -5.87% and a 52-week decline of 29.39%, closing at $52.92 per share on September 23, 2025 [2] - The company underperformed due to uncertainty in the funding environment, influenced by federal funding cuts and a weak venture capital landscape [3] Group 3 - Bio-Techne Corporation generated $317 million in revenues in the fiscal fourth quarter of 2025, reflecting a 3% year-over-year increase on an organic basis and a 4% increase on a reported basis [4] - The company is not among the 30 most popular stocks among hedge funds, with 37 hedge fund portfolios holding its stock at the end of the second quarter, up from 34 in the previous quarter [4] - Despite acknowledging Bio-Techne's potential, the company believes certain AI stocks present greater upside potential and lower downside risk [4]

Company Overview - Bio-Techne Corporation (TECH) is headquartered in Minneapolis, Minnesota, and specializes in developing, manufacturing, and selling life science reagents, instruments, and services for research, diagnostics, and bioprocessing markets, with a market cap of $8.3 billion [1] - The company focuses on proteins, cytokines, growth factors, immunoassays, and small molecules, positioning itself as a significant player in the biotechnology industry [1] Market Position - TECH is classified as a mid-cap stock, with a market cap exceeding $2 billion, highlighting its size, influence, and dominance within the biotechnology sector [2] - The company is committed to innovation, strategic acquisitions, and has a global presence, which positions it for continued success and growth opportunities both domestically and internationally [2] Stock Performance - Despite its strengths, TECH's stock has decreased by 34.5% from its 52-week high of $80.80, reached on November 6, 2024 [3] - Over the past three months, TECH stock gained 7.3%, underperforming the Dow Jones Industrials Average, which gained 8.7% during the same period [3] - Year-to-date, shares of TECH have dipped 26.5%, and over the past 52 weeks, they have fallen 31.5%, significantly underperforming the Dow Jones Industrials Average's YTD gains of 8.8% and 9.9% returns over the last year [4] Recent Financial Results - On August 6, TECH reported its Q4 results, with an adjusted EPS of $0.53, surpassing Wall Street expectations of $0.50, and revenue of $317 million, exceeding forecasts of $315.4 million [5] - In comparison, Adaptive Biotechnologies Corporation (ADPT) has shown significant resilience, with YTD gains of 132.4% and 227% returns over the past 52 weeks, indicating a competitive challenge for TECH [5]

Company Overview - Revvity, Inc. (RVTY) has a market capitalization of $10 billion and is a global provider of health sciences solutions, technologies, and services, offering a wide range of products including instruments, reagents, informatics, software, imaging technologies, DNA sequencing services, and diagnostic platforms for genetic and infectious disease testing [1][2] Stock Performance - Revvity's shares have decreased by 33.1% from their 52-week high of $129.50 and have fallen 8.8% over the past three months, underperforming the Health Care Select Sector SPDR Fund (XLV), which gained 3.7% during the same period [3] - Year-to-date, RVTY stock is down 22.4%, while XLV has experienced a marginal drop. Over the past 52 weeks, Revvity shares have decreased by 29.1%, compared to XLV's 11.2% decline [4] Financial Forecast - On July 28, Revvity's shares fell 8.3% after the company revised its full-year adjusted profit forecast to $4.85 to $4.95 per share, citing weaker demand in China, where diagnostic product sales declined by double digits in Q2 2025 due to new reimbursement policies [5] - The company now expects diagnostics sales growth to be in the low single digits, down from an earlier forecast of mid-single digits [6] Analyst Sentiment - Despite the weak stock performance, analysts maintain a moderately optimistic outlook for Revvity, with a consensus rating of "Moderate Buy" from 18 analysts and a mean price target of $114.62, representing a 33.7% premium to current levels [7]

Core Insights - The Brown Capital Management Small Company Fund experienced an 8.59% return in Q2 2025, underperforming the Russell 2000® Growth index which returned 11.97% [1] - The underperformance was noted to occur in the last few weeks of the quarter [1] Company Highlights - Bio-Techne Corporation (NASDAQ:TECH) is highlighted in the investor letter, with a market capitalization of $7.973 billion [2] - Bio-Techne's one-month return was -3.81%, and it experienced a significant decline of 31.43% over the past 52 weeks, closing at $51.26 per share on September 12, 2025 [2] - Bio-Techne Corporation was identified as a detractor to the fund's performance in Q2 2025 [3]