An updated edition of the June 10, 2025, article.The global cancer treatment market is experiencing rapid growth, driven by rising cancer incidence, aging population and increasing demand for safer, more effective therapies. Per the American Cancer Society, in the United States alone, over 2 million new cancer cases and 618,000 related deaths are projected for 2025.Breakthroughs in immunotherapy, targeted treatments, and personalized cancer vaccines are reshaping the oncology landscape. These next-generatio ...

>> Welcome back to Money Movers. Take a look at shares of Novartis down nearly 3% despite posting a beat on the top and bottom lines. Hiking full year guidance upping the buyback.Swiss pharma company saying its build up of U.S. Inventories will help mitigate the impact of tariffs this year. Joining us to break down the quarters, Novartis CEO Vas Narasimhan. It's great to see you again, boss.Welcome back. >> Thanks, Sarah. Great to be with you.>> I mean, there's so much going on in your sector and there's a ...

Core Insights - Novartis AG reported better-than-expected Q2 2025 results, with core earnings of $2.42 per share, surpassing the Zacks Consensus Estimate of $2.38 and up from $1.97 a year ago, driven by strong sales growth [1][6] - Revenues reached $14.05 billion, a 12% increase from the previous year, exceeding the Zacks Consensus Estimate of $14.04 billion [1][6] Sales Performance - On a constant currency basis, sales increased by 11%, supported by strong performances from key drugs including Kisqali, Entresto, Kesimpta, Scemblix, Leqvio, and Pluvicto [2][6] - Entresto's sales rose 22% to $2.36 billion, driven by heart failure indications in the U.S. and Europe, and hypertension indications in China and Japan, beating estimates [5][6] - Kisqali's sales surged 64% to $1.2 billion, with strong growth in the U.S. due to recent launches [8] - Kesimpta sales totaled $1.1 billion, up 33%, driven by increased demand [9] - Cosentyx sales increased 6% to $1.6 billion but missed estimates, impacting investor sentiment [7][6] - Pluvicto sales reached $454 million, up 30%, following FDA approval for earlier use, significantly expanding the eligible patient population [12] - Leqvio sales soared 61% to $298 million, driven by steady demand growth [13] Financial Guidance and Strategic Moves - Novartis raised its 2025 core operating income growth outlook to low teens, reflecting strong product and pipeline performance [6][16] - The company initiated a $10 billion share buyback plan, expected to be completed by 2027 [17] - Novartis acquired Regulus Therapeutics Inc. for $0.8 billion, with potential additional payments based on regulatory milestones [21] Management Changes - CFO Harry Kirsch announced his retirement, with Mukul Mehta appointed as the new CFO, effective March 15, 2026 [18]

Novartis (NVS) reported $14.05 billion in revenue for the quarter ended June 2025, representing a year-over-year increase of 9.2%. EPS of $2.42 for the same period compares to $1.97 a year ago.The reported revenue represents a surprise of +0.13% over the Zacks Consensus Estimate of $14.04 billion. With the consensus EPS estimate being $2.38, the EPS surprise was +1.68%.While investors scrutinize revenue and earnings changes year-over-year and how they compare with Wall Street expectations to determine their ...

Core Insights - Novartis anticipates Kisqali to become a blockbuster drug, shifting focus from Entresto [1] - Kisqali sales increased by 64% globally in Q2, with 100% growth in the U.S. [1] - The company reported a 56% increase in Kisqali sales in Q1 [2] Industry Trends - Global breast cancer diagnoses and deaths are expected to rise significantly by 2050, with 1 in 20 women projected to be diagnosed [2] - This could lead to 3.2 million new cases and 1.1 million deaths annually by 2050, compared to 2.3 million new cases and 670,000 deaths in 2022 [3] Company Pipeline - Novartis has a strong pipeline with other potential blockbusters like Pluvicto for prostate cancer and Scemblix for chronic myeloid leukemia [3] - The company is focused on driving performance for Kisqali, Pluvicto, and Scemblix, indicating a strategy to replace reliance on older therapies [3]

Novartis (NVS) Q2 2025 Earnings Call July 17, 2025 08:00 AM ET Company ParticipantsSloan Simpson - Global Head - IRVasant Narasimhan - CEOHarry Kirsch - CFOSachin Jain - Vice PresidentShirley Chen - AVPPeter Verdult - MD - Pharmaceuticals Equity researchSimon Baker - Partner & Head - Global Biopharma ResearchRichard Vosser - Managing DirectorMichael Leuchten - Managing DirectorHarry Sephton - Director - Equity ResearchJames Quigley - Executive DirectorKerry Holford - Head - Global Pharma Equity ResearchThib ...

Novartis (NVS) Q2 2025 Earnings Call July 17, 2025 08:00 AM ET Speaker0morning and good afternoon, and welcome to the Novartis Q2 twenty twenty five Results Release Conference Call and Live Webcast. Please note that during the presentation, all participants will be in a listen only mode and the conference is being recorded. After the presentation, there'll be an opportunity to ask questions. A recording of the conference call, including the Q and A session, will be available on our website shortly after the ...

Q2 2025 Financial Performance - Novartis delivered double-digit sales growth and core margin expansion in Q2 2025 [134] - Q2 sales reached USD 141 billion, an increase of 11% in constant currencies (cc) compared to Q2 2024 [14] - Core operating income for Q2 2025 was USD 59 billion, a 21% increase in constant currencies (cc) compared to Q2 2024 [14] - Core margin improved to 422%, a 340 basis points increase [14] - Free cash flow for H1 2025 increased by 46% to USD 97 billion [104] FY 2025 Guidance and Capital Allocation - FY 2025 core operating income guidance upgraded to low-teens growth from low double-digit [15] - A new share buyback program of up to USD 10 billion was initiated, to be completed by the end of 2027 [108] - The company assumes Entresto US generic entry in mid-2025 for forecasting purposes [112] Key Products Performance - Kisqali grew by 64% cc in Q2, achieving TRx leadership in mBC [23] - Kesimpta grew by 33% cc in Q2, driven by strong demand growth [31] - Pluvicto grew by 30% cc in Q2, with promising uptake since pre-taxane indication approval in the US [36] - Leqvio grew by 61% cc in Q2, on track for blockbuster status in 2025 [45] - Scemblix grew by 79% cc in Q2, with strong momentum in early lines and global leadership in 3L+ CML [52]

Core Viewpoint - Novartis reported strong Q2 2025 results with double-digit growth in net sales and core operating income, driven by successful product launches and pipeline advancements, alongside a commitment to a significant share buyback program [3][4][5]. Financial Performance - Q2 2025 net sales reached USD 14.1 billion, a 12% increase year-over-year, with constant currency growth of 11% [4][30]. - Operating income for Q2 2025 was USD 4.9 billion, reflecting a 21% increase, while net income rose to USD 4.0 billion, up 24% [4][9]. - Core operating income was USD 5.9 billion, a 20% increase, with a core operating income margin of 42.2% [10][30]. - Free cash flow for Q2 2025 was USD 6.3 billion, a 37% increase compared to the previous year [10][30]. - For H1 2025, net sales totaled USD 27.3 billion, up 12%, and core operating income increased by 21% to USD 11.5 billion [11][13]. Product Performance - Key growth drivers included Kisqali (+64% cc), Entresto (+22% cc), Kesimpta (+33% cc), Scemblix (+79% cc), Leqvio (+61% cc), and Pluvicto (+30% cc) [5][16]. - The top 20 brands generated USD 11.6 billion in Q2 2025, with a 16% increase year-over-year [17][18]. Strategic Initiatives - Novartis announced an up-to USD 10 billion share buyback program to enhance shareholder returns [3][5]. - The company raised its full-year 2025 guidance for core operating income growth to low teens, while maintaining high single-digit sales growth expectations [5][28]. Research and Development - Significant pipeline milestones included positive Phase III results for Pluvicto in hormone-sensitive prostate cancer and FDA approval for Vanrafia for IgAN [5][19][21]. - Ongoing trials and studies showed promising results for various therapies, including Kisqali and Scemblix, with plans for further regulatory submissions [22][23]. Capital Structure - As of June 30, 2025, net debt increased to USD 23.8 billion, primarily due to cash outflows for dividends and share repurchases [26]. - The company maintains a strong capital structure with a focus on balanced capital allocation [24][25].

Core Insights - Novartis AG is set to report its second-quarter 2025 results on July 17, with revenue expectations at $14.04 billion and earnings at $2.38 per share [1] - The company has a strong earnings surprise history, beating estimates in the last four quarters with an average surprise of 7.12% [1] Earnings Prediction - The Earnings ESP for Novartis is -0.28%, indicating a lower likelihood of an earnings beat this quarter [3] - The company currently holds a Zacks Rank of 2 (Buy) [3] Growth Drivers - Novartis operates in four core therapeutic areas: cardiovascular-renal-metabolic, immunology, neuroscience, and oncology following the spin-off of the Sandoz business [4] - Key products driving growth include Entresto, Kisqali, Kesimpta, Leqvio, and Scemblix, with strong sales expected in Q2 [4][8] Product Performance - Entresto's sales are estimated at $2.3 billion, benefiting from increased demand in China and Japan [5] - Kisqali's sales are projected at $1 billion, driven by its recognition in breast cancer treatment [6][7] - Kesimpta's sales are also expected to reach $1 billion, reflecting increased demand [7] - Cosentyx is anticipated to generate sales of $1.73 billion, supported by recent launches and volume growth [9] - Leqvio's sales estimates are $284 million, indicating strong growth in cholesterol management [10] - Pluvicto's sales are projected at $410 million, bolstered by FDA approval for expanded use [11] - Scemblix continues to see growth in chronic myeloid leukemia treatment, with strong demand expected [12] Recent Developments - Novartis acquired Regulus Therapeutics for $0.8 billion, adding farabursen to its pipeline, which targets autosomal dominant polycystic kidney disease [14] - Year-to-date, Novartis shares have increased by 27.3%, significantly outperforming the industry average of 1.8% [15]