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MORRISVILLE, N.C., June 23, 2025 (GLOBE NEWSWIRE) -- Liquidia Corporation (NASDAQ: LQDA), a biopharmaceutical company developing innovative therapies for patients with rare cardiopulmonary disease, today announced the receipt of an additional $50.0 million under its sixth amendment to its financing agreement (HCR Agreement) with Healthcare Royalty (HCRx) upon the U.S. District Court for the Middle District of North Carolina denying United Therapeutics Corporation’s request for a preliminary injunction and t ...

Group 1: S&P 500 and Russell Reconstitution - The S&P 500 index represents approximately 80% of the total U.S. equity market, making its quarterly rebalancing significant for investors [1] - The addition of stocks to the S&P 500 often leads to increased institutional buying, which can elevate stock prices, as seen with Palantir Technologies Inc. in 2024 [1] - Investors interested in small- to mid-cap stocks are focused on the Russell Reconstitution, which will conclude on June 27 [2] Group 2: Sprouts Farmers Market (SFM) - Sprouts Farmers Market Inc. has seen its stock increase over 500% in the last five years, aligning with the trend of health-conscious consumers [4] - The stock has a current price of $161.86, with a 12-month price forecast of $167.79, indicating a potential upside of 3.66% [4] - SFM's market cap is around $15 billion, and the stock has increased more than 100% in the last 12 months, despite being considered expensive with a P/E ratio over 25x compared to mainstream grocery stocks [6] Group 3: Insmed Inc. (INSM) - Insmed Inc. has experienced a stock price increase of over 47% in the last month due to positive Phase IIb trial data for its drug treating pulmonary arterial hypertension [9] - The current stock price is $99.46, with a 12-month price forecast of $104.81, suggesting a 5.38% upside [9] - Institutional buying has increased in the last two quarters, reflecting a more bullish analyst sentiment following the company's last earnings report [11] Group 4: FTAI Aviation Inc. (FTAI) - FTAI Aviation Inc. has climbed 8.9% in the last month, driven by increased demand for jet engine leasing and aftermarket services [12] - The stock has a current price of $130.08, with a 12-month price forecast of $171.83, indicating a potential upside of 32.10% [12] - Despite a recent rally, FTAI stock is still down over 10% in 2025, but analysts are raising their price targets, suggesting potential upside for investors [14]

Core Insights - Insmed Inc experienced a significant stock surge of 45% in the last month, driven by successful Phase IIb trial results for its inhalation therapy TPIP in pulmonary arterial hypertension (PAH) [2] - The company is currently trading at a high valuation of 35 times sales, which translates to a low sales yield of 2.8%, raising concerns about its sustainability [3] - Insmed's stock premium is primarily attributed to the positive trial results and a $750 million capital raise aimed at pipeline expansion, leading to investor optimism [4][5] Financial Performance - Insmed projects global revenues for its product ARIKAYCE to be between $405 million and $425 million in 2025, indicating an 11-17% growth compared to 2024 [6] - The company is expected to remain unprofitable into 2026 due to ongoing investments in research and development for pipeline products [6] Future Outlook - The FDA's decision on brensocatib in August and the initiation of Phase 3 trials for TPIP are critical upcoming milestones that could significantly impact Insmed's stock performance [7] - Successful execution of Phase 3 trials and commercial launches of both brensocatib and TPIP will be essential for maintaining the current premium valuation [7][8]

Company Overview - United Therapeutics (UTHR) shares increased by 3.5% to close at $286.14, following a period of decline where the stock lost 7.7% over the past four weeks [1] - The rise in share price is linked to a recovery after a decline due to positive results from a pulmonary arterial hypertension (PAH) study conducted by Insmed, which evaluated a prodrug formulation of UTHR's treprostinil [2] Financial Performance - United Therapeutics is expected to report quarterly earnings of $6.87 per share, reflecting a year-over-year increase of 17.4% [3] - Revenue projections for the upcoming quarter stand at $796.42 million, which is an 11.4% increase compared to the same quarter last year [3] Earnings Estimates and Market Sentiment - The consensus EPS estimate for United Therapeutics has been revised 0.7% higher in the last 30 days, indicating a positive trend that typically correlates with stock price appreciation [4] - The company currently holds a Zacks Rank of 3 (Hold), suggesting a neutral outlook in the market [4] Industry Context - United Therapeutics operates within the Zacks Medical - Drugs industry, where BioCryst Pharmaceuticals (BCRX) is another player, having closed 2% lower at $10.40 [4] - BioCryst's consensus EPS estimate remains unchanged at $0.02, representing a significant year-over-year change of 133.3% [5]

June 10, 2025 Topline Results of Phase 2b Study of TPIP in PAH Patients TPIP: Treprostinil Palmitil Inhalation Powder | PAH: pulmonary arterial hypertension The forward-looking statements in this presentation are based upon the Company's current expectations and beliefs, and involve known and unknown risks, uncertainties and other factors, which may cause the Company's actual results, performance and achievements and the timing of certain events to differ materially from the results, performance, achievemen ...

–The Study Met Primary and All Secondary Efficacy Endpoints– –TPIP Was Well Tolerated in the Study, with 75% of Patients Titrating to the Highest Dose– –Insmed to Immediately Engage with FDA to Inform Phase 3 Trial Design with Studies Expected to Begin Before End of 2025 for PH-ILD and in Early 2026 for PAH– –Insmed to Host Investor Call at 8:00 AM ET on Tuesday, June 10, 2025– BRIDGEWATER, N.J., June 10, 2025 /PRNewswire/ -- Insmed Incorporated (Nasdaq: INSM), a people-first global biopharmaceutical compan ...

Core Insights - Liquidia Corporation has announced the first commercial shipment of YUTREPIA™ (treprostinil) inhalation powder, following FDA approval on May 23, 2025, for treating pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD) [1][6] - The company has moved quickly to promote YUTREPIA, with its sales force actively engaging in the market just over a week after FDA approval [2] - A recent court ruling denied United Therapeutics' request for a preliminary injunction against Liquidia, allowing for the full commercial launch of YUTREPIA [2] Company Overview - Liquidia Corporation is a biopharmaceutical company focused on developing innovative therapies for rare cardiopulmonary diseases, particularly in pulmonary hypertension [9] - The company utilizes its proprietary PRINT technology to create drug formulations, including YUTREPIA, which is designed for enhanced lung deposition [5][9] - Liquidia is also developing L606, a sustained-release formulation of treprostinil, and markets generic Treprostinil Injection for PAH treatment [9] Product Information - YUTREPIA is an inhaled dry-powder formulation of treprostinil, delivered through a user-friendly device, aimed at providing a new therapeutic option for patients with PAH and PH-ILD [5][6] - The product was previously known as LIQ861 during investigational studies and has undergone clinical trials to establish its safety and efficacy [5] Disease Context - PAH is a rare, chronic disease affecting approximately 45,000 patients in the U.S., with no current cure, making symptom management and quality of life improvement critical [3] - PH-ILD encompasses a range of pulmonary diseases affecting over 60,000 patients in the U.S., with associated poor survival rates [4]

Group 1 - The U.S. FDA approved Liquidia Corporation's LQDA Yutrepia (treprostinil) inhalation powder for adults with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD) to improve exercise ability [1] - In August 2024, the FDA issued tentative approval of Yutrepia for the PAH and PH-ILD indications [1] - Following the announcement, Liquidia shares fell 5.2% to trade at $14.80 [1] Group 2 - Wells Fargo analyst Tiago Fauth maintained an Overweight rating on Liquidia and raised the price target from $20 to $23 [6] - HC Wainwright & Co. analyst Andrew Fein maintained a Buy rating and raised the price target from $29 to $35 [6] - Needham analyst Serge Belanger reiterated a Buy rating and maintained a $25 price target [6]

Core Insights - Liquidia Corporation will provide a business update during a fireside chat at the 2025 Jefferies Global Healthcare Conference on June 4, 2025 [1] - The event will feature key executives including the CEO, CFO, and Chief Business Officer [1] Company Overview - Liquidia Corporation is a biopharmaceutical company focused on developing innovative therapies for rare cardiopulmonary diseases [3] - The company is currently developing and commercializing products for pulmonary hypertension using its proprietary PRINT Technology [3] - Liquidia's approved product, YUTREPIA™ (treprostinil) inhalation powder, is used for treating pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PHILD) [3] - The company is also working on L606, an investigational sustained-release formulation of treprostinil, and markets generic Treprostinil Injection for PAH treatment [3]