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CMS (867.HK/8A8.SG): NDA for Additional Indication Atopic Dermatitis (AD) for Ruxolitinib Phosphate Cream Accepted and Granted Priority Review in China
Globenewswire· 2026-02-24 13:32
Core Viewpoint - China Medical System Holdings Limited's subsidiary, Dermavon Holdings Limited, has received acceptance from the National Medical Products Administration of China for the New Drug Application of ruxolitinib phosphate cream for treating mild to moderate atopic dermatitis, which is expected to accelerate the marketing approval process [1][4]. Group 1: Product Development and Approval - Ruxolitinib phosphate cream has been approved for marketing by the NMPA for the treatment of vitiligo and is now expanding its indications to atopic dermatitis, marking a significant milestone in its therapeutic applications [2]. - The NDA for ruxolitinib phosphate cream has been included in the Priority Review List, reducing the review timeline from 200 days to 130 days, which is anticipated to expedite the product's availability to patients [4]. Group 2: Clinical Trial Results - The product demonstrated robust efficacy in a Phase III clinical trial, achieving a significantly higher proportion of subjects reaching an Investigator's Global Assessment score of 0 or 1 compared to placebo (63.0% vs 9.2%, P < 0.001) [6]. - For the secondary endpoint, 78.0% of subjects treated with ruxolitinib phosphate cream achieved at least a 75% improvement in the Eczema Area and Severity Index score compared to 15.4% in the placebo group (P < 0.001) [6]. Group 3: Market Potential and Strategic Positioning - Atopic dermatitis affects over 54 million patients in China, with mild to moderate cases accounting for 98% of these, indicating a substantial market opportunity for ruxolitinib phosphate cream [5]. - Dermavon is developing a comprehensive "treatment + care" solution for atopic dermatitis, which includes ruxolitinib phosphate cream and other therapeutic options, enhancing its leadership in dermatology [6][7]. - The acceptance of the NDA for atopic dermatitis is expected to strengthen Dermavon's strategic positioning in skin treatments and create synergies with its existing product portfolio, potentially enhancing market competitiveness [8].
Playboy Reports Preliminary Fourth Quarter 2025 Financial Results
Globenewswire· 2026-02-24 13:31
Core Insights - Playboy, Inc. expects Q4 2025 revenues to be between $34.0 million and $35.0 million, showing growth from $33.5 million in Q4 2024 [1][6] - The company anticipates a net income of between $2.5 million and $3.5 million, a significant recovery from a net loss of $12.5 million in Q4 2024 [1][6] - Adjusted EBITDA is projected to be between $6.6 million and $7.0 million, compared to a loss of $0.1 million in Q4 2024 [1][6] Financial Performance - Revenue growth is attributed to the strength of the global licensing business, supported by a joint venture with UTG Brands Management Group in China [3][6] - The expected net income includes approximately $1.2 million in transaction costs related to the China licensing joint venture and $0.9 million in litigation costs [6] - The improvement in adjusted EBITDA reflects successful execution of an asset-light strategy and ongoing cost reduction initiatives [6] Management Commentary - The CEO of Playboy highlighted the significant progress in executing the company's strategic transformation, emphasizing revenue growth and strides towards sustainable profitability [3] - The company is focused on leveraging its iconic brand for sustainable, profitable growth as it enters 2026 [4] - Complete financial results for Q4 and fiscal year 2025 are expected to be reported in March 2026 [4]
Reborn Coffee Announces Strategic Distribution Partnership with Sysco to Support National Franchise Expansion
Globenewswire· 2026-02-24 13:31
Core Insights - Reborn Coffee Inc. has entered into a distribution partnership with Sysco Corporation to enhance its supply chain capabilities and support its franchise expansion strategy across the United States [1][2][5] Group 1: Partnership Details - The partnership with Sysco is aimed at improving supply chain execution and standardizing distribution support for both existing and future franchise operators [2][3] - Reborn Coffee will leverage Sysco's distribution network and service capabilities to enhance fulfillment reliability and streamline purchasing processes [3][4] Group 2: Operational Improvements - The collaboration is expected to provide access to quality assurance resources, food safety protocols, and operational tools, which will help stores execute more consistently [3][4] - The structured framework for product delivery will allow franchise operators to focus more on customer experience and revenue-generating operations [4] Group 3: Company Background - Reborn Coffee is a California-based specialty coffee retailer focused on delivering high-quality, handcrafted coffee experiences and is redefining the coffeehouse model through innovation [7] - Sysco, as the global leader in food distribution, operates 340 distribution centers in over 10 countries and generated sales of more than $78 billion in fiscal year 2024 [5][6]
EVA Live Announces Fast Quote Direct™ — A Disruptive AI Quoting Engine Targeting the Online Lead Generation Industry
Globenewswire· 2026-02-24 13:30
Core Insights - EVA Live, Inc. has launched Fast Quote Direct™, an AI-powered quoting engine aimed at transforming the online services and lead generation industry [1][2] - The platform is designed to convert high-intent traffic into qualified customers through an automated quoting experience [2][4] Company Overview - EVA Live, Inc. is focused on delivering innovative AI-driven media and digital solutions, aiming for scalable growth and long-term shareholder value [8] Product Features - Fast Quote Direct replaces traditional online forms with a dynamic AI-driven interface that guides users through the quoting process in real time [3] - The platform analyzes user responses instantly, matching consumers with appropriate providers across various service categories, including financial services and insurance [3][5] - It utilizes adaptive AI learning to refine targeting and matching, improving accuracy and reducing issues like fraud and incomplete submissions [5] Market Position - Fast Quote Direct is expected to disrupt the online lead generation industry, which is estimated to be worth between $1.6 billion and $3 billion annually in the U.S. [7] - The platform is anticipated to enhance EVA's role from merely generating traffic to full-cycle customer acquisition [7] Future Plans - Fast Quote Direct is currently in beta testing with select partners and is expected to launch commercially in phases throughout 2026 [6] - The platform will function both as an integrated component of the NeuroServer ecosystem and as a standalone SaaS product [6]
Tampa General Hospital is the First Health System in Florida to Adopt the LIBERTY® Endovascular Robotic System
Globenewswire· 2026-02-24 13:30
Early Post-Clearance Momentum Signals Accelerated Hospital Adoption of Advanced RoboticsHINGHAM, Mass., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Microbot Medical Inc. (Nasdaq: MBOT), developer and distributor of the innovative LIBERTY® Endovascular Robotic System, announced today that Tampa General Hospital has become the first health system in Florida to adopt LIBERTY, marking another important milestone following the Company’s recent FDA 510(k) clearance. Microbot believes that this reflects early post-clearance ...
ECGI Holdings and Nomyx Begin Live Pilot to Tokenize Up to $10 Million in Mortgage Loans on RezyFi
Globenewswire· 2026-02-24 13:30
Core Insights - ECGI Holdings, Inc. has initiated a pilot program to tokenize up to $10 million of mortgage loans originated by its subsidiary ResMac, with the platform launch expected within 45 to 60 days pending pilot completion [1][2] Group 1: Pilot Program Details - The pilot aims to validate a repeatable infrastructure layer for mortgage assets, focusing on how loans can be represented on-chain through various stages such as origination and lifecycle events [2][4] - Nomyx Technology Labs Inc. will provide the necessary modular infrastructure to support the tokenization workflow, compliance, and platform integration [3] - The pilot will assess transaction throughput, cost efficiency, and ecosystem compatibility across public blockchain networks before the commercial launch [4][5] Group 2: Market Context and Expectations - The Mortgage Bankers Association projects that total single-family mortgage originations will rise to $2.2 trillion in 2026, up from $2.0 trillion in 2025, indicating a substantial addressable market for mortgage tokenization [4] - ECGI plans to provide updates on pilot milestones during the testing period, focusing on workflow completion and launch readiness [5] - The partnership with Nomyx is expected to modernize the management of mortgage assets, which are seen as under-digitized in the financial markets [5]
CDT Equity Notes Sarborg Expansion into Bacteria and Agrochemicals
Globenewswire· 2026-02-24 13:30
NAPLES, Fla. and CAMBRIDGE, United Kingdom, Feb. 24, 2026 (GLOBE NEWSWIRE) -- CDT Equity Inc. (Nasdaq: CDT) (“CDT” or the “Company”), today notes the announcement issued this morning by Sarborg Limited regarding the expansion of its proprietary AI Signature Agent platform beyond pharmaceuticals into bacteria and agrochemicals. CDT holds a significant 20% equity stake in Sarborg and views this expansion as a meaningful strategic development in the continued evolution of Sarborg’s cross-industry signature int ...
Where Food Comes From, Inc. Schedules 2025 Year-End Earnings Call
Globenewswire· 2026-02-24 13:30
Core Viewpoint - Where Food Comes From, Inc. (WFCF) will release its 2025 financial results on February 26, 2026, before market opening, followed by a conference call at 10:00 a.m. Mountain Time [1] Company Overview - Where Food Comes From, Inc. is recognized as a trusted resource for third-party verification of food production practices in North America [2] - The company supports over 17,500 stakeholders in the food industry, including farmers, ranchers, processors, retailers, and restaurants, through various value-added services [2] - Its proprietary technology and patented business processes are utilized to verify food claims, optimize production practices, and enhance food supply chains with analytics and data-driven insights [2] - The company's labeling program, Where Food Comes From®, employs web-based customer education tools to connect consumers with the sources of their food, fostering meaningful engagement for clients [2]
Champion Safe Accelerates Dealer-Led Growth Through Utah’s A1 Safe & Vault at the Western Hunting & Conservation Expo 2026
Globenewswire· 2026-02-24 13:30
American Rebel Holdings Inc Western Hunting & Conservation Expo 2026 American Rebel Holdings Inc Champion Vault Doors: Unmatched Security and Craftsmanship American Rebel Holdings Inc The Western Hunting & Conservation Expo: A Premier Industry Event Premium Champion Safes and vault doors made with American-steel, paired with A1’s expert delivery and installation, create repeatable retail wins—driving higher sell-through potential and increased reorders across Utah. Provo, UT, Feb. 24, 2026 (GLOB ...
TRWD Advances National Roll-Up Strategy
Globenewswire· 2026-02-24 13:30
NEW YORK, Feb. 24, 2026 (GLOBE NEWSWIRE) -- Tradewinds Universal (OTC: TRWD), a fully reporting holding company focused on acquiring and integrating revenue-producing assets, today provided an update regarding its progress toward its planned structured roll-up integration strategy with Peppermint Hippo. Peppermint Hippo and its affiliated entities currently operate more than 10 venues nationwide, including eight Peppermint Hippo branded clubs alongside affiliated concepts such as Las Tóxicas. The operating ...