Core Insights - The company reported a significant increase in total revenue for the first half of 2025, achieving approximately RMB 1.178 billion, which represents a year-on-year growth of 112% [1][2] - The sales volume of the core product, Huadongning® (Dapagliflozin Tablets), reached 1.764 million boxes, marking a 108% increase compared to the same period last year [1][2] - The company achieved a gross profit margin of approximately 54.2%, an increase of 7.7% year-on-year, indicating improved operational efficiency [1] - The termination of the exclusive promotion agreement with Bayer resulted in a one-time deferred income of RMB 12.435 billion, contributing to a net profit of RMB 1.184 billion for the reporting period, marking the company's first profitable period [1][2] - The company has a cash balance of approximately RMB 1.023 billion, providing a solid financial foundation for future growth [1] Business Development - The company has fully transitioned to independent commercialization of Huadongning® in China as of January 1, 2025, reflecting strong market demand and effective execution by its sales team [2] - The company is actively pursuing registration of Dapagliflozin in Hong Kong and seeking partnerships in Southeast Asia and Belt and Road countries [2] - Based on preliminary success from Phase I single-dose escalation studies in the U.S., the company plans to initiate Phase I multi-dose escalation studies by the end of 2025 or early 2026, aiming to expand the global market for the second-generation GKA [2]

Core Insights - HuaLing Pharmaceutical (02552) reported significant growth in its mid-term performance for the six months ending June 30, 2025, with sales of Huatangning® reaching 1.764 million boxes, a year-on-year increase of 108%, and net sales of 217.4 million yuan, up 112% [1] - The company achieved a profit of 1.1839 billion yuan for the first time during this reporting period, marking a successful commercial transformation after taking over the commercialization of Huatangning® in January 2025 [1] - The gross margin improved to 54.2%, an increase of 7.7 percentage points compared to the same period last year, indicating a positive trend in profitability [1] Group 1 - HuaLing Pharmaceutical is actively expanding its overseas business and accelerating its global layout, having submitted a registration application for Myhomsis (75mg) in Hong Kong [2] - The company plans to initiate a multi-dose escalation Phase I study by the end of 2025 or early 2026 based on preliminary success from a Phase I single-dose escalation study in the U.S. [2] - A Phase I clinical study supported by HuaLing Pharmaceutical at the University of Pennsylvania has been approved by the FDA to evaluate the efficacy and safety of Myhomsis in patients with cystic fibrosis-related diabetes (CFRD) [2] Group 2 - The company is committed to continuous innovation and market expansion, aiming to enhance its position on the international stage [3] - HuaLing Pharmaceutical's founder and CEO, Dr. Chen Li, emphasized the dual-driven approach of innovative R&D and market expansion to benefit more global patients with original Chinese drugs [3]

Core Insights - Hualing Pharmaceutical (02552) reported significant growth in its mid-term performance for the six months ending June 30, 2025, with sales of Huatangning reaching 1.764 million boxes, a year-on-year increase of 108%, and net sales of 217.4 million yuan, up 112% [1] - The company achieved a profit of 1.1839 billion yuan for the first time during this reporting period, marking a successful transition to commercialization after taking over the operations of Huatangning [1] - The gross profit margin improved to 54.2%, an increase of 7.7 percentage points compared to the same period last year, indicating a positive trend in profitability [1] Domestic Market Performance - The significant increase in prescriptions from secondary and tertiary hospitals was supported by the expansion of medical insurance coverage [1] - The company has successfully implemented a self-operated sales team, contributing to the notable growth in sales [1] International Expansion - Hualing Pharmaceutical is actively expanding its overseas business, having submitted a registration application for Myhomsistm (Dapagliflozin 75mg) in Hong Kong, which will accelerate its presence in Greater China and Southeast Asia [2] - The company plans to initiate a multi-dose escalation Phase I study by the end of 2025 or early 2026 based on the preliminary success of its Phase I single-dose escalation study in the U.S. [2] - A Phase I clinical study supported by Hualing Pharmaceutical at the University of Pennsylvania has received FDA approval to evaluate the efficacy and safety of Dapagliflozin in patients with cystic fibrosis-related diabetes (CFRD) [2] Research and Development - The company is conducting a real-world study involving 80 centers and 2,000 type 2 diabetes patients in China, further confirming the broad applicability and safety of Dapagliflozin [2] - New research results in diabetes remission and cognitive improvement reinforce Hualing Pharmaceutical's global leadership in GKA research and treatment [2] Future Outlook - With ongoing international market expansion and continuous advancement of its research pipeline, Hualing Pharmaceutical is expected to play a more significant role on the global stage [3] - The company's CEO, Dr. Chen Li, emphasized the commitment to driving innovation and market expansion to benefit more global patients with original Chinese drugs [3]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內容而產生或因依賴 該等內容而引致的任何損失承擔任何責任。 HUA MEDICINE 華領醫藥 （於開曼群島註冊成立的有限公司） （股份代號：2552） 截至2025年6月30日止六個月的中期業績公告 董事會欣然宣佈本集團截至2025年6月30日止六個月未經審核綜合業績連同截至 2024年6月30日止六個月的比較數字。除另有界定者外，本公告所用詞彙與招股 章程所界定者具有相同涵義。 業務摘要 上半年公司轉型變革，华堂宁®銷售額快速增長，同比增長逾一倍，並在強勁的 商業執行及運營效率提升的帶動下，明顯轉向盈利。 1 • 於2025年上半年，我們銷售約1,764,000盒华堂宁®，較2024年同期所出售 的846,000盒增長108%。於2025年上半年，我們獨自負責所有商業銷售， 而2024年則由第三方進行商業銷售。兩個期間的單價保持不變。 • 收入同比增長112%至人民幣217.4百萬元，反映出我們在終止與拜耳的獨 家推廣服務協議後順利過渡到全面自主商業化，並擴大 ...

Group 1 - The Hong Kong biotechnology stocks experienced a collective decline, with notable drops in several companies [1] - WuXi AppTec (02126) saw a decrease of 12.95%, closing at 4.840 [2] - BioNTech (06952) fell by 12.53%, with a latest price of 13.750 [2] Group 2 - Other companies such as Valiant (09887) and Beihai Kangcheng (01228) also reported significant declines of 9.93% and 9.75% respectively [2] - The decline extended to companies like Saint Noble (02257) and MIRXES (02629), which dropped by 9.64% and 8.43% [2] - Overall, the biotechnology sector is facing downward pressure, impacting multiple firms [1]

Group 1 - The company, Hualing Pharmaceutical-B (02552.HK), has scheduled a board meeting on August 28, 2025, to consider and approve the interim results for the six months ending June 30, 2025, along with related announcements and other matters [1]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部份內容而產生或因倚 賴該等內容而引致的任何損失承擔任何責任。 董事會召開日期 華領醫藥（「本公司」及其附屬公司「本集團」）董事會（「董事會」）茲通告，本公司 謹定於2025年8月28日（星期四）舉行董事會會議，以考慮及通過本集團截至2025 年6月30日止的六個月中期業績，及有關公佈，以及處理其他事項。 承董事會命 行政總裁兼執行董事 陳力博士 香港，2025年8月18日 於本公告日期，董事會成員包括執行董事陳力博士、林潔誠先生及張怡博士；非 執行董事Robert Taylor Nelsen先生；以及獨立非執行董事William Robert Keller先 生、徐耀華先生及張耀樑先生。 HUA MEDICINE 華領醫藥 （於開曼群島註冊成立的有限公司） （股份代號：2552） ...

Core Insights - Chinese innovative drugs currently account for 38% of the global market [1] - In the previous year, 39 innovative drugs were launched, while 30 have already been launched in the first half of this year [1] - China is capable of developing globally first-in-class innovative drugs, exemplified by Hualing Pharmaceutical's Huatangning, which can reverse diabetes and prevent complications [1] Industry Summary - The growth of innovative drug development in China is significant, with a notable increase in the number of drugs launched annually [1] - The successful market entry of innovative drugs like Huatangning demonstrates China's potential in advanced scientific concepts and technologies [1] - The inclusion of innovative drugs in China's medical insurance indicates a supportive regulatory environment for the pharmaceutical industry [1]

股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 | 截至月份: | 2025年7月31日 | | | | 狀態: 新提交 | | --- | --- | --- | --- | --- | --- | | 致：香港交易及結算所有限公司 | | | | | | | 公司名稱: | 華領醫藥 | | | | | | 呈交日期: | 2025年8月6日 | | | | | | I. 法定/註冊股本變動 | | | | | | | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | 於香港聯交所上市 (註1) | 是 | | 證券代號 (如上市) | 02552 | 說明 | 普通股 | | | | | 法定/註冊股份數目 | 面值 | | 法定/註冊股本 | | | --- | --- | --- | --- | --- | --- | | 上月底結存 | 2,000,000,000 | USD | 0.001 | USD | 2,000,000 | | 增加 / 減少 (-) | | | | USD | | | 本月底結存 | 2,000,000,000 | USD | 0. ...

每经AI快讯，8月6日，截至发稿，晶泰控股(02228.HK)涨15%、华领医药-B(02552.HK)涨4.62%、歌礼 制药-B(02509.HK)涨2.35%。 ...