Core Viewpoint - The company reported a slight revenue beat in Q1 2025, with adjusted Non-IFRS net profit slightly below expectations, primarily due to higher-than-expected losses from non-operating items [1] Revenue Performance - Q1 2025 revenue reached RMB 3.099 billion, representing a 16% year-over-year increase but a 10.4% quarter-over-quarter decline, slightly above expectations [1] - Laboratory services and clinical research services outperformed expectations, contributing to revenue growth [1][2] Segment Analysis - Laboratory services revenue grew by 15.7% YoY and 1.6% QoQ, with gross margin slightly improving by 1.4 percentage points YoY and 0.2 percentage points QoQ [2] - CMC services revenue increased by 19.1% YoY but decreased by 31.5% QoQ, with a gross margin improvement of 2.5 percentage points YoY [2] - Clinical research services revenue rose by 14.2% YoY and fell by 14% QoQ, with gross margin also improving by 2.5 percentage points YoY [2] - CGT revenue grew by 7.9% YoY and 2.2% QoQ, although gross margin declined significantly by 30.3 percentage points YoY due to increased operational and depreciation costs [2] Order Growth - Overall new orders in Q1 2025 achieved a growth rate of over 10% YoY, with CMC's backlog orders growing by over 20% YoY [3] - Management maintains a revenue guidance of 10%-15% growth for the full year 2025, despite a slowdown in new order growth compared to previous quarters [3] External Factors - The impact of tariffs on the company is limited, with minimal reliance on U.S. sourced materials, and the company is well-prepared with sufficient inventory [4] - The recovery of overseas biopharmaceutical financing remains slow, with only signs of moderate recovery in VC financing [4] Investment Rating - The company maintains a "Buy" rating, with target prices set at HKD 20 for Hong Kong shares and RMB 32 for A-shares, reflecting a premium of 80% for A-shares compared to Hong Kong shares [5]

得益于创新药投融资复苏和新签订单回暖，公司业绩逐步改善。 事件：公司发布了2025 年第一季度报告，2025Q1 公司实现营收30.99 亿元，同比增长16.03%；实现归 母净利润3.06 亿元，同比增长32.54%。 得益于创新药投融资复苏和新签订单回暖，公司业绩逐步改善： 收入端，2025Q1 公司实现营收30.99 亿元，同比增长16.03%。其中，实验室服务、CMC、临床研究服 务、大分子和细胞与基因治疗服务分别实现营收18.57 亿元（+15.74%）、6.93 亿元（+19.05%）、4.47 亿元（+14.25%）、0.99 亿元（+7.94%）。 新签订单回暖且项目陆续交付，核心业务稳步发展： 利润端，2025Q1 公司实现归母净利润3.06 亿元，同比增长32.54%。 投资建议： 预计2025 年-2027 年公司的归母净利润分别为19.28 亿元、21.48 亿元、23.89 亿元；预计2025 年EPS 为 1.08 元/股，给予25 倍PE，对应6 个月目标价为27.00 元/股，给予买入-A 的投资评级。 风险提示：新药研发失败风险；海外政策不确定性风险：CXO 行业竞争加剧风险 ...

智通财经4月29日电，截至发稿，药明康德(02359.HK)涨4.90%、凯莱英(03759.HK)涨2.71%、昭衍新药 (06127.HK)涨1.87%。 部分港股医药外包概念股走强 药明康德涨近5% ...

Summary of the Conference Call for 康龙化成 (Crown Bioscience) Q1 2025 Company Overview - 康龙化成 reported a revenue of 30.96 billion CNY in Q1 2025, representing a year-on-year growth of 15.4% [2][3] - The company maintains its revenue growth guidance for 2025 at 10% to 15% and expects to continue generating positive free cash flow [2][9] Key Financial Performance - The adjusted net profit for Q1 2025 was 3.49 billion CNY, a year-on-year increase of 3.1%, while the net profit attributable to shareholders was 3.06 billion CNY, up 32.5% [3][4] - The laboratory services segment generated 18.57 billion CNY, with a gross margin of 45.5%, up 1.4 percentage points [2][5] - The small molecule CDMO services segment reported revenue of 6.93 billion CNY, with a gross margin of 30.4%, an increase of 2.5 percentage points [2][5] - Clinical services revenue was 4.47 billion CNY, with a gross margin of 11.8%, up 2.5 percentage points [2][5] - The revenue from large molecule and cell & gene therapy services was 99 million CNY, showing a year-on-year growth of 7.9% [2][5] Revenue Breakdown by Region and Client Type - Revenue from Chinese laboratories and factories grew by 15.7%, accounting for 88% of total revenue; overseas revenue increased by 18.3%, making up 12% [2][6] - North American client revenue rose by 16.8%, representing 65% of total revenue; European client revenue increased by 26%, accounting for 18% [2][6] Order Growth and Market Trends - New orders maintained a double-digit growth of over 10% in Q1 2025, continuing the trend from the previous year [2][7] - The CMC business is focused on early clinical stages, with expectations for several large projects to advance into later stages, which will enhance CMC revenue and overall performance [4][23] Strategic Initiatives and Future Outlook - The company is investing in advanced technologies in the biosciences field, including 3D cell culture and organ-on-a-chip models, to stay at the forefront of industry developments [4][12] - The company anticipates that the adjusted net profit growth will accelerate from Q2 2025 onwards as operational efficiencies improve [3][4] - The overall market for laboratory services and biosciences is expected to continue its recovery, with double-digit growth anticipated in both sectors [9][20] Challenges and Considerations - The company faces challenges related to increased operational costs and depreciation due to new capacity coming online in 2024 [4][3] - The impact of geopolitical factors, such as tariffs and the IRA Act, on client R&D and production needs is being monitored, but the company remains optimistic about its growth trajectory [14][19] Conclusion - 康龙化成's Q1 2025 performance reflects strong growth across its segments, with a positive outlook for the remainder of the year, driven by strategic investments and a robust order pipeline [29]

智通财经APP获悉，截止4月17日，未平仓空单比位列前三位为药明康德（02359）、赣锋锂业 （01772）、万科企业（02202），空仓比分别为15.63%、14.23%、13.24%。 未平仓空单比（绝对值）较上一次减少最多为再鼎医药（09688）、美的集团（00300）、康龙化成 （03759），分别减少-1.31%、-0.80%、-0.76%。 前10大未平仓空仓比 | 股票名称 | 前次空仓数 | 本次空仓数 | 最新空仓比↓ | | --- | --- | --- | --- | | 药明康德(02359) | 6168.69 万股 | 6050.95 万股 | 15.63% | | 赣锋锂业(01772) | 5893.42 万股 | 5743.15 万股 | 14.23% | | 万科企业(02202) | 2.59 亿股 | 2.92 亿股 | 13.24% | | 中兴通讯(00763) | 9237.00 万股 | 9472.26 万股 | 12.54% | | BRILLIANCE CHI(01114) | 6.18 亿股 | 6.15 亿股 | 12.18% | | 福莱特玻璃(06 ...

智通财经APP获悉，国投证券发布研报称，根据Crunchbase的数据，2024年全球和美国创新药VC&PE投 融资金额分别同比增长1.93%和5.29%，2024年全球和美国创新药VC&PE投融资情况已恢复正增长，创 新药投融资环境已逐步改善；热门赛道研发方面，多肽、ADC等领域研发需求旺盛，推动相关领域研 发外包需求提升。目前CXO上市公司相关订单开始逐步改善且产能处于行业领先地位，看好CXO上市 公司业绩边际改善，其中，在订单方面，药明康德、药明合联、凯莱英、康龙化成、博腾股份等多家上 市公司新签/在手订单已及时回暖。 国投证券主要观点如下： 宏观维度：全球创新药投融资持续改善，研发需求复苏可期 根据Frost& Sullivan的数据，预计全球肽类药物的研发生产服务外包的市场规模从2025年的47亿美元增 长至2032年188亿美元，全球ADC药物的研发生产服务外包的市场规模有望从2022年的15亿美元增长至 2030年的110亿美元。 微观维度：新签订单及时回暖，看好2025年CXO业绩改善 目前CXO上市公司相关订单开始逐步改善且产能处于行业领先地位，看好CXO上市公司业绩边际改 善。其中，订单方 ...

Investment Rating - The report maintains a "Buy-A" investment rating with a target price of 27.00 CNY per share for the next six months [4][6]. Core Insights - The company has shown a recovery in new orders and project deliveries, leading to improved performance in Q1 2025, with revenue reaching 3.099 billion CNY, a year-on-year increase of 16.03%, and a net profit of 306 million CNY, up 32.54% year-on-year [1][2][3]. Revenue and Profit Growth - The revenue breakdown for Q1 2025 includes laboratory services at 1.857 billion CNY (+15.74%), CMC at 693 million CNY (+19.05%), clinical research services at 447 million CNY (+14.25%), and large molecule and cell & gene therapy services at 99 million CNY (+7.94%) [2][3]. - The company expects a revenue growth of 10%-15% year-on-year for 2025, driven by a recovery in the innovative drug investment and financing sector [3]. Financial Projections - The projected net profits for 2025, 2026, and 2027 are 1.928 billion CNY, 2.148 billion CNY, and 2.389 billion CNY respectively, with an expected EPS of 1.08 CNY per share for 2025 [4][5]. - The report anticipates a steady increase in revenue from 13.792 billion CNY in 2025 to 17.759 billion CNY in 2027 [5][11]. Market Performance - As of April 25, 2025, the company's stock price was 23.19 CNY, with a market capitalization of approximately 41.236 billion CNY [6][7]. - The stock has shown a 12-month absolute return of 27.1% [7].

Financial Performance - The company's revenue for Q1 2025 reached ¥3,098,813,569.89, representing a 16.03% increase compared to ¥2,670,740,738.16 in the same period last year[6] - Net profit attributable to shareholders was ¥305,575,186.04, up 32.54% from ¥230,557,834.70 year-on-year[6] - The adjusted net profit attributable to shareholders was ¥349,441,031.17, reflecting a 3.14% increase from ¥338,816,299.13 in the previous year[6] - Total revenue for the period reached CNY 3,098,813,569.89, an increase of 15.9% compared to CNY 2,670,740,738.16 in the previous period[35] - Net profit for the period was CNY 279,654,565.09, representing a 29.5% increase from CNY 215,919,833.12 in the prior period[36] - The company reported a profit before tax of RMB 363,587,000, compared to RMB 268,619,000 in the previous year, an increase of 35.4%[42] - Total comprehensive income for the period reached RMB 389,670,737.53, compared to RMB 162,642,198.05 in the previous period, representing an increase of approximately 139.5%[37] Revenue Breakdown - Revenue from laboratory services was ¥1,857,202,616.77, a 15.74% increase from ¥1,604,576,678.01 year-on-year, with a gross margin of 45.54%[8] - Revenue from CMC (small molecule CDMO) services was ¥693,023,486.59, up 19.05% from ¥582,104,488.92, with a gross margin of 30.44%[8] - Revenue from clinical research services reached ¥447,320,929.08, a 14.25% increase from ¥391,531,326.06, with a gross margin of 11.76%[8] - Revenue from the top 20 global pharmaceutical companies was ¥455,746,000, a 29.05% increase, accounting for 14.71% of total revenue[9] Shareholder Metrics - Basic earnings per share increased by 33.54% to CNY 0.1736, reflecting the growth in net profit attributable to shareholders[14] - Diluted earnings per share rose by 33.51% to CNY 0.1733, also attributed to the increase in net profit[15] - The total number of common shareholders at the end of the reporting period was 79,841[20] - The company announced a profit distribution plan for the year 2024, which is expected to enhance shareholder value[28] Cash Flow and Assets - The company's cash flow from operating activities amounted to ¥852,829,144.27, a 14.38% increase compared to ¥745,630,586.78 in the same period last year[6] - Cash flow from investing activities resulted in a net outflow of RMB 1,212,095,238.52, worsening from a net outflow of RMB 467,094,044.67 in the previous period[40] - Cash flow from financing activities showed a net outflow of RMB 98,926,715.92, an improvement compared to a net outflow of RMB 1,512,600,594.24 last period[41] - The total current assets decreased from CNY 7,608,179,522.72 to CNY 7,384,443,685.17, representing a decline of approximately 2.95%[30] - Cash and cash equivalents decreased from CNY 1,689,916,082.15 to CNY 1,262,763,166.96, a reduction of about 25.3%[30] Expenses and Liabilities - Total operating costs amounted to CNY 2,713,717,115.43, up from CNY 2,439,362,705.75, reflecting a growth of 11.2%[35] - Research and development expenses grew by 30.56% to CNY 122,210,590.15, indicating a continued commitment to R&D investment[18] - Income tax expenses rose by 59.27% to CNY 83,932,205.84, corresponding to the increase in total profit[19] - The total liabilities decreased slightly to CNY 9,686,700,206.35 from CNY 9,704,526,037.38, a reduction of 0.2%[33] Other Financial Metrics - Other comprehensive income increased significantly by 1,370.30% to CNY 98,545,941.98, driven by foreign currency translation differences and cash flow hedging[18] - The company's total non-current assets increased to CNY 16,948,379,035.81 from CNY 16,319,218,798.51, marking a growth of 3.9%[31] - The equity attributable to the parent company increased to RMB 14,042,172 thousand from RMB 13,619,335 thousand, marking a growth of 3.1%[44] - The company's goodwill increased to RMB 2,947,429 thousand from RMB 2,760,736 thousand, reflecting a growth of 6.8%[43]

证券代码：300759 证券简称：康龙化成 公告编号：2025-026 康龙化成（北京）新药技术股份有限公司 关于非执行董事辞职暨 补选公司第三届董事会非执行董事的公告 事会任期届满之日止。 胡柏风先生在任职期间勤勉尽责，致力于公司的规范运作和健康发展，并凭 借自身积累的丰富投资经验，为公司可持续发展提供了诸多宝贵建议，公司董事 会对胡柏风先生在任职期间为公司及董事会所做出的贡献表示衷心感谢！ 特此公告。 康龙化成（北京）新药技术股份有限公司董事会 2025 年 4 月 28 日 2 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 康龙化成（北京）新药技术股份有限公司（以下简称"公司"）于 2025 年 4 月 25 日召开第三届董事会第十四次会议，审议通过了《关于补选公司第三届董 事会非执行董事的议案》。胡柏风先生因本职工作调整，申请辞去公司第三届董 事会非执行董事及董事会战略委员会委员职务（第三届董事会原定任期至 2026 年 6 月 20 日），辞职后胡柏风先生将不再担任公司任何职务。胡柏风先生自愿继 续履行非执行董事及董事会战略委员会委员职责至公司股东 ...

证券代码：300759 证券简称：康龙化成 公告编号：2025-024 康龙化成（北京）新药技术股份有限公司 第三届董事会第十四次会议决议公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 一、董事会会议召开情况 康龙化成（北京）新药技术股份有限公司（以下简称"公司"）第三届董事 会第十四次会议于 2025 年 4 月 25 日上午 11：00 以通讯方式召开，本次会议通 知及会议材料于 2025 年 4 月 11 日以邮件形式向全体董事发出。会议应出席董事 8 名，实际出席董事 8 名。本次会议由公司董事长 Boliang Lou 博士主持，公司 部分高级管理人员列席了本次会议。本次会议的召集和召开符合《中华人民共和 国公司法》等有关法律、行政法规、部门规章、规范性文件和《康龙化成（北京） 新药技术股份有限公司章程》的规定。 二、董事会会议审议情况 与会董事审议并以记名投票方式通过了以下议案： （一）审议通过《关于 2025 年第一季度报告的议案》 董事会认为：公司编制的《2025 年第一季度报告》符合法律、行政法规、中 国证监会和深圳证券交易所的规定，报 ...