Core Viewpoint - The article discusses the upcoming 2025 Shanghai Leading Industries and the 14th Pharmaceutical CEO Forum, highlighting the focus on innovation and global expansion of Chinese pharmaceutical companies [1]. Summary by Sections Event Overview - The event will take place on September 4-5, 2025, at the Mandarin Oriental Hotel in Pudong, Shanghai, featuring nearly a hundred executives from listed companies, including chairpersons, CEOs, and industry leaders [4]. Morning Sessions - The morning session on September 4 will include a keynote speech and several roundtable discussions focusing on topics such as the global expansion of Chinese pharmaceutical companies and the search for the next billion-dollar drug [4][5]. - Notable discussions will include: - "From Local Innovation to Global Leadership: The Era of Chinese Pharmaceutical Companies Going Abroad" [4]. - "The Birth of Big Drugs is the Future of Pharmaceuticals: Finding the Next Billion-Dollar Bomb" [4]. Afternoon Sessions - The afternoon will feature discussions on future disease areas and technologies worth exploring for pharmaceutical assets going abroad, as well as the new cycle of Chinese innovative drugs under global competition [5][6]. - Additional topics will cover advancements in drug development platforms and the emerging field of brain-machine interfaces [6]. TMT Forum - The TMT (Technology, Media, and Telecommunications) forum will also take place, discussing AI's impact on various industries, including gaming and healthcare [7][8]. - Key topics will include AI innovations in mobile internet ecosystems and the future of AI in healthcare [7]. Pharmaceutical Sub-Forum - The pharmaceutical sub-forum will address topics such as ADC technology exploration, probiotic delivery systems, and the future development paths of dual antibodies and XDC [8]. - Discussions will also focus on the integration of medical insurance and the innovative practices in building a multi-level medical security system in China [8].

Core Viewpoint - Junshi Bioscience has shown significant stock price appreciation in 2023, with a year-to-date increase of 73.14% and notable gains over various trading periods [2]. Group 1: Stock Performance - As of September 3, Junshi Bioscience's stock price reached 47.32 CNY per share, with a market capitalization of 48.583 billion CNY [1]. - The stock has increased by 9.08% over the last 5 trading days, 14.63% over the last 20 days, and 29.22% over the last 60 days [2]. Group 2: Financial Performance - For the first half of 2025, Junshi Bioscience reported revenue of 1.168 billion CNY, representing a year-on-year growth of 48.64% [2]. - The company recorded a net profit attributable to shareholders of -413 million CNY, which is a 36.01% increase compared to the previous period [2]. Group 3: Shareholder Information - As of June 30, 2025, the number of shareholders for Junshi Bioscience increased to 31,200, up by 5.88% from the previous period [2]. - The average number of circulating shares per shareholder decreased by 5.56% to 24,543 shares [2]. Group 4: Institutional Holdings - As of June 30, 2025, the top ten circulating shareholders include Huaxia SSE STAR 50 ETF, which holds 29.7167 million shares, a decrease of 536,700 shares from the previous period [3]. - E Fund SSE STAR 50 ETF increased its holdings to 22.2132 million shares, an increase of 630,000 shares [3].

FF301 股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年8月31日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 上海君實生物醫藥科技股份有限公司 呈交日期: 2025年9月3日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | | 於香港聯交所上市 (註1) | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 01877 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 260,295,700 | RMB | | 1 RMB | | 260,295,700 | | 增加 / 減少 (-) | | | 0 | | | RMB | | 0 | | 本月底結存 | | | 260,295,700 | RMB | | 1 RMB | | 260,295,700 | | 2. 股份分類 | 普通股 | 股份類別 ...

FF301 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | | 於香港聯交所上市 (註1) | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 01877 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 260,295,700 | RMB | | 1 RMB | | 260,295,700 | | 增加 / 減少 (-) | | | 0 | | | RMB | | 0 | | 本月底結存 | | | 260,295,700 | RMB | | 1 RMB | | 260,295,700 | | 2. 股份分類 | 普通股 | 股份類別 | A | | 於香港聯交所上市 (註1) | 否 | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 688180 | 說明 | | ...

Group 1 - The company, Junshi Biosciences, announced the approval of multiple proposals during the ninth meeting of its fourth supervisory board, including a proposal to grant stock options to a director and major shareholder [2] - The announcement was made on the evening of September 2 [2] - The proposals are part of the company's ongoing governance and incentive strategies [2]

Core Viewpoint - Junshi Biosciences announced the approval of multiple proposals during the 11th meeting of its fourth board of directors, including a proposal to grant stock options to a director and major shareholder [2] Group 1 - The board meeting was held on September 2, where significant resolutions were made [2] - The proposal regarding stock options is aimed at aligning the interests of the director with those of the shareholders [2]

Group 1 - The core point of the article is that Junshi Biosciences announced the approval of a clinical trial application for its drug JT118 injection by the National Medical Products Administration [1] Group 2 - The approval was granted to Junshi's subsidiary, Shanghai Juntao Biopharmaceutical Technology Co., Ltd [1] - The announcement was made on the evening of September 2 [1]

Group 1: 恒瑞医药 - Company received approval for clinical trials of HRS-7172 tablets, a new anti-tumor small molecule inhibitor [1] - Subsidiary received approval for SHR-A2009, an antibody-drug conjugate targeting HER3 [1] - Company was established in April 1997, focusing on drug research, production, and sales [1] Group 2: 康德莱 - Controlling shareholder plans to transfer 5% of shares to strategic investor at a price of 10.81 yuan per share, totaling 236 million yuan [1] - Post-transfer, controlling shareholder's stake will decrease from 39.58% to 34.58% [1] - Company was established in July 1998, specializing in medical devices [2] Group 3: 中钢洛耐 - Shareholder plans to reduce holdings by up to 1% of total shares due to fund exit needs [3] - Company was established in August 2006, focusing on high-end refractory materials [3] Group 4: 瑞玛精密 - Subsidiary completed acquisition of land in Mexico for production operations, covering 52,300 square meters at a price of 3.4064 million USD [4] - Company was established in March 2012, specializing in precision metal stamping and related products [4] Group 5: 鸿博股份 - Company confirmed normal operations despite stock price fluctuations exceeding 20% over three trading days [5] - Company was established in June 1999, focusing on lottery services and high-end packaging [6] Group 6: 东芯股份 - Company completed stock trading risk investigation and resumed trading [7] - Company was established in November 2014, specializing in storage chip design and sales [7] Group 7: 凯迪股份 - Company stated that its robot products are still in development and will not generate revenue in the short term [8] - Company was established in August 1992, focusing on linear drive systems [8] Group 8: 诺唯赞 - Major shareholder plans to reduce holdings by up to 3% due to funding needs [9] - Company was established in March 2012, focusing on functional proteins and organic materials [9] Group 9: 君实生物 - Company received approval for clinical trials of JT118 injection, a "two-in-one" recombinant protein vaccine for monkeypox [10] - Company was established in December 2012, focusing on new drug research and related services [10] Group 10: 赛力斯 - Company reported August sales of 45,818 vehicles, with a 19.57% increase in new energy vehicle sales [11] - Company was established in September 2012, focusing on automotive research and sales [11] Group 11: 燕东微 - Major shareholder plans to reduce holdings by up to 1% due to management needs [13] - Company was established in October 1987, focusing on semiconductor products and services [13] Group 12: 中百集团 - Company reported cumulative litigation and arbitration amounts of approximately 262 million yuan over the past 12 months [14] - Company was established in January 1990, focusing on retail business [14] Group 13: 金开新能 - Company received 939 million yuan in renewable energy subsidies, with a 341.67% increase year-on-year [15] - Company was established in March 1997, focusing on renewable energy development and operation [15] Group 14: *ST天茂 - Company plans to terminate stock listing and initiate cash option mechanism for shareholders [16] - Company was established in November 1993, focusing on various insurance services [16] Group 15: 宁德时代 - Company repurchased 8.69 million A-shares for a total of 2.131 billion yuan [17] - Company was established in December 2011, focusing on battery research and production [17] Group 16: 山西高速 - Controlling shareholder plans to increase holdings by 30 to 60 million yuan [18] - Company was established in February 1996, focusing on highway management [18] Group 17: 青岛银行 - Major shareholder plans to increase holdings by 233 to 291 million shares [19] - Company was established in November 1996, focusing on banking services [19] Group 18: 格力电器 - Major shareholder completed share increase of 46.38 million shares for 2.099 billion yuan [20] - Company was established in December 1989, focusing on air conditioning production and sales [20] Group 19: 中国石油 - Company plans to transfer 541 million A-shares to China Mobile Group to enhance strategic cooperation [21] - Company was established in November 1999, focusing on oil and gas exploration and production [21] Group 20: 镇洋发展 - Company announced a merger plan with Zhejiang Huhangyong Highway Co., with a share exchange ratio of 1:1.08 [22] - Company was established in December 2004, focusing on chemical products [22]

Market Overview - The market experienced fluctuations with the ChiNext index leading the decline, while the total trading volume in the Shanghai and Shenzhen markets reached 2.87 trillion yuan, an increase of 125 billion yuan compared to the previous trading day [1] - Over 4,000 stocks in the market saw declines, with sectors such as banking, precious metals, robotics, and oil showing the most significant gains [1] Industry News - The "High-Quality Standard System Construction Plan for Industrial Mother Machines" was officially issued by two departments, leading to a surge in the industrial mother machine concept stocks, with companies like Hengjin Induction, Huadong CNC, and Bojie Shares hitting the daily limit [1] - The robotics sector also experienced a boost from this news, with Zhejiang Rongtai reaching a historical high and other companies like Top Group, Longxi Shares, and Qin Chuan Machine Tool also hitting the daily limit [1] Company Updates - Kedi Shares announced that its robotics-related business is still in the development stage and will not generate revenue in the short term, which is not expected to significantly impact the company's performance [2] - Seres reported that its August new energy vehicle production reached 43,069 units, a year-on-year increase of 19.38%, while sales were 43,262 units, up 19.57% year-on-year [3] - Junshi Biosciences received approval for clinical trials of its JT118 injection, a "two-in-one" recombinant protein vaccine aimed at preventing monkeypox virus infection, marking a significant development as no such vaccine has been approved in China yet [4]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或因倚 賴該等內容而引致的任何損失承擔任何責任。 SHANGHAI JUNSHI BIOSCIENCES CO., LTD.* 上海君實生物醫藥科技股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：1877） (1)建議採納2025年H股股票期權激勵計劃； (2)建議向承授人授予H股股票期權； (3)建議採納2025年A股股票期權激勵計劃；及 (4)建議向一名董事兼主要股東授予A股股票期權 建議採納2025年H股股票期權激勵計劃和2025年A股股票期權激勵計劃 於2025年9月2日，董事會已審議及批准（其中包括）(i)建議採納2025年H股股票 期權激勵計劃；及(ii)採納2025年A股股票期權激勵計劃。根據上市規則第十七 章，2025年H股股票期權激勵計劃及2025年A股股票期權激勵計劃將構成本公 司涉及發行新股份的股份計劃，因此採納2025年H股股票期權激勵計劃及2025 年A股股票期權激勵計劃須獲股東批准。 建議向承授人授予及 ...