证券日报网讯诺禾致源11月25日在互动平台回答投资者提问时表示，截至2025年9月30日，公司股东户 数为9680户。 ...

Core Insights - On November 21, 2023, Nuohe Zhiyuan's stock fell by 4.01%, with a trading volume of 70.51 million yuan [1] - The company reported a financing buy-in of 7.14 million yuan and a financing repayment of 8.28 million yuan, resulting in a net financing outflow of 1.14 million yuan [1] - As of November 21, the total margin balance for Nuohe Zhiyuan was 130 million yuan, which is 2.33% of its market capitalization [1] Financing Summary - On the same day, the financing buy-in was 7.14 million yuan, with a current financing balance of 130 million yuan, exceeding the 60th percentile level over the past year [1] - The margin trading showed a repayment of 300 shares and a sell-out of 400 shares, with a sell-out amount of 5,356 yuan [1] - The margin balance was 136,500 yuan, which is below the 30th percentile level over the past year [1] Company Overview - Nuohe Zhiyuan, established on March 15, 2011, and listed on April 13, 2021, is located in Beijing and provides gene testing and bioinformatics analysis services [1] - The company's revenue composition includes: sequencing platform services (50.03%), life sciences basic research services (34.05%), medical research and technology services (13.37%), and others (2.54%) [1] Financial Performance - As of September 30, 2023, Nuohe Zhiyuan reported a total revenue of 1.581 billion yuan for the first nine months of 2023, representing a year-on-year growth of 4.05% [2] - The net profit attributable to shareholders was 113 million yuan, showing a year-on-year decrease of 16.05% [2] Shareholder Information - As of September 30, 2023, the number of shareholders was 9,680, a decrease of 1.24% from the previous period [2] - The average number of circulating shares per person increased by 1.26% to 42,995 shares [2] - Cumulative cash dividends since the A-share listing amount to 82.47 million yuan, with 58.45 million yuan distributed in the last three years [3]

Core Viewpoint - The company, Novogene, is focusing its research and development expenses on emerging businesses such as single-cell, spatial omics, proteomics, metabolomics, epigenetics, and long-read sequencing technologies, as part of its planned R&D activities [1] Summary by Categories - **Research and Development Focus** - The company is allocating its R&D expenses primarily towards new and emerging fields [1] - Specific areas of investment include single-cell analysis, spatial omics, proteomics, metabolomics, epigenetics, and long-read sequencing technologies [1]

Investment Rating - The investment rating has been downgraded to "Outperform" [1][4] Core Insights - The company reported a revenue of RMB 1.58 billion for the first nine months of 2025, a 4.05% increase from RMB 1.52 billion in the same period of 2024. Q3 2025 revenue was RMB 541 million, up 3.47% year-on-year. However, net profit for the same period was RMB 116 million, down 17.34% year-on-year, with a net profit margin of 7.31%. Q3 2025 net profit was RMB 34 million, down 40.90% year-on-year. The forecasted EPS for 2025-2027 is RMB 0.44, 0.50, and 0.60 respectively, with a target price of RMB 15.36 based on a PE of 35X for 2025. The downgrade is attributed to the anticipated slow growth in gene sequencing services [4][11][12]. Financial Summary - Total revenue projections are as follows: - 2023A: RMB 2,002 million - 2024A: RMB 2,111 million - 2025E: RMB 2,197 million - 2026E: RMB 2,441 million - 2027E: RMB 2,716 million - Net profit (attributable to the parent) is projected as: - 2023A: RMB 178 million - 2024A: RMB 197 million - 2025E: RMB 183 million - 2026E: RMB 210 million - 2027E: RMB 249 million - The net profit margin is expected to fluctuate, with a decrease in 2025E [3][6][11]. R&D and Strategic Investments - The company has maintained high R&D investment, with R&D expenses reaching RMB 119 million from January to September 2025, a 50.48% increase year-on-year, accounting for 7.51% of revenue. Q3 2025 R&D expenses were RMB 56.10 million, focusing on emerging fields such as single-cell, spatial omics, and proteomics [12][13]. - The company is also investing in global expansion and customer engagement, which has led to increased R&D expenses and fluctuations in gross profit margin [12][14]. Sales and Marketing Expenses - Sales expenses have slightly increased due to global localization and marketing upgrades, with a sales expense ratio of 20.38% from January to September 2025, up 0.76 percentage points year-on-year. The Q3 2025 sales expense ratio was 21.06%, up 1.43 percentage points year-on-year [14].

Core Insights - Beijing Nuohe Yuanqi Gene Technology Co., Ltd. has been established with a registered capital of 30 million yuan [1] - The company is wholly owned by Nuohe Zhiyuan [1] - The business scope includes natural science research and experimental development, medical research and experimental development, biotechnology product technology research and development, and electronic product sales [1] Company Overview - The legal representative of the newly established company is Yu Yang [1] - The company focuses on various research and development activities in the fields of natural sciences and biotechnology [1]

Summary of the Conference Call for 诺禾致源 (Nuohe Zhiyuan) Company Overview - **Company**: 诺禾致源 (Nuohe Zhiyuan) - **Period**: January to September 2025 Key Financial Metrics - **Total Revenue**: 15.81 billion CNY, up 4.05% year-on-year [2][3] - **Q3 Revenue**: 5.41 billion CNY, up 3.47% year-on-year [3] - **Overseas Revenue**: 7.92 billion CNY, up 4.1% year-on-year, accounting for 50.09% of total revenue [2][3] - **Q3 Overseas Revenue**: 2.58 billion CNY, down 0.48% year-on-year [3] - **Domestic Revenue**: 7.89 billion CNY, up 4% year-on-year [2] - **Q3 Domestic Revenue**: 2.82 billion CNY, up 7.37% year-on-year, and up 8.61% quarter-on-quarter [5] - **Gross Margin**: 41.9%, down 0.7 percentage points year-on-year [10] - **Net Profit**: 1.16 billion CNY, down 10.17% year-on-year, with a net profit margin of 7.31% [11] - **R&D Investment**: 56.1 million CNY in Q3, focusing on emerging fields [12] Revenue Breakdown by Market - **Americas**: Q3 revenue down 12% due to changes in research funding and policy impacts [4] - **EMEA**: Q3 revenue down 12%, affected by project completion and funding transitions [4] - **Europe**: Q3 revenue up 19%, indicating strong performance [4] - **Customer Segmentation**: 70% of revenue from universities and research institutions, 30% from hospitals and enterprises [6] Product and Service Performance - **Life Sciences Research Services**: Revenue of 5.52 billion CNY, up 6.21% year-on-year [7] - **Monitoring and Sequencing Platform Services**: Revenue of 7.7 billion CNY, up 3.23% year-on-year, but Q3 revenue down 3.42% [7] - **Emerging Business Contributions**: Approximately 32% of total revenue, up 4 percentage points year-on-year, with a growth of about 20% [8] R&D and Innovation - **R&D Focus Areas**: Single-cell genomics, spatial genomics, proteomics, metabolomics, epigenetics, and long-read sequencing [12][18] - **AI Integration**: Progress in AI applications, particularly in omics data analysis and virtual cell modeling [20][28] Market Challenges and Strategies - **Domestic Market Competition**: Increased competition leading to a 30% price drop; company aims to reduce competition through mergers and acquisitions [16][23] - **Geopolitical Impact**: U.S. market affected by geopolitical tensions, but the company maintains strong relationships in key regions [21] - **Cash Flow Management**: Operating cash flow was negative 87 million CNY for the first nine months, but turned positive in Q3 at 77 million CNY [14] Future Outlook - **Expansion Plans**: Continued investment in overseas markets, including new laboratories in Singapore and Europe [30] - **Focus on NGS and AI**: Anticipated growth in NGS applications and AI integration to enhance research capabilities [24][28] Additional Insights - **Customer Base Growth**: Stable customer structure with a slight increase in contributions from universities and research institutions [6] - **Cash Flow Volatility**: Short-term fluctuations in cash flow due to proactive risk management strategies [14] - **Regulatory Environment**: Ongoing adjustments to align with changing policies in the domestic and international markets [26][27]

Core Viewpoint - The company announced a provision for asset impairment totaling approximately 24.53 million yuan to reflect its financial status and operational results as of September 30, 2025 [2] Financial Assessment - The company conducted a comprehensive evaluation of its financial assets, inventory, and long-term assets to determine potential impairment losses [2] - The impairment provision was made in accordance with the "Enterprise Accounting Standards" and the company's accounting policies and estimates [2] Meeting Announcement - The fourth meeting of the fourth board of directors is scheduled for October 23, 2025, to review the asset impairment provision proposal [2]

Group 1 - The core viewpoint of the article is that 诺禾致源 (688315.SH) reported its Q3 2025 financial results, showing mixed performance with revenue growth but declining net profits [1] Group 2 - The company achieved a revenue of 1.581 billion yuan in the first three quarters, representing a year-on-year increase of 4.05% [1] - The net profit attributable to shareholders was 113 million yuan, reflecting a year-on-year decrease of 16.05% [1] - The non-recurring net profit was 90.02 million yuan, down 19.35% year-on-year [1] - The basic earnings per share stood at 0.28 yuan [1]

Group 1 - The core point of the article is that 诺禾致源 announced a credit impairment loss and asset impairment loss totaling 24.53 million yuan for the first three quarters of 2025, which reduced the pre-tax profit and owner's equity accordingly [1] - For the year 2024, the revenue composition of 诺禾致源 indicates that 99.66% of its revenue comes from gene sequencing professional technical services, while other businesses contribute only 0.34% [1] - As of the report date, 诺禾致源 has a market capitalization of 6.1 billion yuan [1]

证券代码：688315 证券简称：诺禾致源 公告编号：2025-039 会 议 召 开 地 点 ： 上 海 证 券 交 易 所 上 证 路 演 中 心 （ 网 址 ： https://roadshow.sseinfo.com/） 会议召开方式：上证路演中心网络互动 投资者可于 2025 年 11 月 10 日（星期一）至 11 月 16 日（星期日）16:00 前 登录上证路演中心网站首页点击"提问预征集"栏目或通过公司邮箱 ir@novogene.com 进行提问。公司将在说明会上对投资者普遍关注的问题进行回 答。 北京诺禾致源科技股份有限公司（以下简称"公司"）已于 2025 年 10 月 24 日发布公司 2025 年第三季度报告，为便于广大投资者更全面深入地了解公司 2025 年第三季度经营成果、财务状况，公司计划于 2025 年 11 月 17 日下午 13:00-14:00 举行 2025 年第三季度业绩说明会，就投资者关心的问题进行交流。 北京诺禾致源科技股份有限公司 关于召开 2025 年第三季度业绩说明会的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏 ...