Core Insights - Robbins Geller Rudman & Dowd LLP is investigating potential violations of U.S. federal securities laws involving ALT5 Sigma Corporation, focusing on whether the company and its executives made false or misleading statements or failed to disclose material information to investors [1][2] Company Overview - ALT5 Sigma provides blockchain-powered technologies through its Fintech and Biotechnology segments [2] - On August 11, 2025, ALT5 Sigma announced plans to raise approximately $1.5 billion before fees through a registered direct offering and a private placement offering [2] Recent Developments - On August 29, 2025, ALT5 Sigma disclosed a judgment from the Intermediate Court of Nyarugenge, Rwanda, finding its subsidiary criminally liable for offenses including illicit enrichment and money laundering [3] - An independent committee was appointed by the Board to investigate potential misstatements or omissions in the financial statements [3] - On October 22, 2025, Peter Tassiopoulos was suspended as CEO, effective immediately, with pay [3] - ALT5 Sigma announced on November 18, 2025, that it would not file its Quarterly Report on Form 10-Q for that quarter in a timely manner [3] - A leadership overhaul occurred on November 27, 2025, with the rapid departures of the CFO, Acting CEO, and COO, alongside the appointment of a new Acting CEO and an experienced CFO [3] - On November 28, 2025, ALT5 Sigma's independent registered public accounting firm resigned due to the retirement of its sole partner [3] - On December 3, 2025, ALT5 Sigma received a notice from Nasdaq regarding non-compliance with listing requirements due to the resignation of a Board member [3]

Core Viewpoint - Altimmune, Inc. (ALT) has shown a significant price increase of 28.4% over the past four weeks, with a mean price target of $17.88 indicating a potential upside of 229.3% from the current price of $5.43 [1] Price Targets and Analyst Consensus - The average price target for ALT includes eight short-term estimates ranging from a low of $1.00 to a high of $28.00, with a standard deviation of $8.81, indicating variability in analyst predictions [2] - The lowest estimate suggests a decline of 81.6%, while the highest points to an upside of 415.7% [2] - A low standard deviation among price targets suggests a strong agreement among analysts regarding the stock's price direction, which can be a useful starting point for further research [9] Earnings Estimates and Analyst Optimism - Analysts have shown increasing optimism about ALT's earnings prospects, as indicated by a strong consensus in revising EPS estimates higher, which correlates with potential stock price increases [11] - Over the last 30 days, the Zacks Consensus Estimate for the current year has increased by 1.8%, with one estimate moving higher and no negative revisions [12] - ALT holds a Zacks Rank 2 (Buy), placing it in the top 20% of over 4,000 ranked stocks based on earnings estimate factors, indicating strong potential for upside [13] Caution on Price Targets - While the consensus price target is a commonly referenced metric, relying solely on it for investment decisions may not be prudent due to historical inaccuracies in predicting actual stock price movements [3][7] - Analysts often set optimistic price targets influenced by business relationships, which can lead to inflated estimates [8] - Investors should approach price targets with skepticism and consider them as one of many factors in their decision-making process [10]

LAS VEGAS--(BUSINESS WIRE)--ALT5 Sigma Corporation (the "Company,†"our†or "ALT5†) (NASDAQ: ALTS) (FRA:5AR1), a fintech company with established global payments, trading, and settlement infrastructure, today released a strategic overview on the USD1 stablecoin, its relevance to ALT5's core long-term payments technology product, and the anticipated benefits to the Company's $WLFI Treasury Strategy. Why USD1 Matters to ALT5 ALT5 is a leading holder of $WLFI, the governance token of the World Lib. ...

Bragar Eagel & Squire, P.C. Litigation Partner Brandon Walker Encourages Investors Who Suffered Losses In ALT5 (ALTS) To Contact Him Directly To Discuss Their Options If you purchased or acquired ALT5 stock and would like to discuss your legal rights, call Bragar Eagel & Squire partner Brandon Walker or Melissa Fortunato directly at (212) 355-4648. Click here to participate in the action. NEW YORK, Dec. 09, 2025 (GLOBE NEWSWIRE) -- What’s Happening: Bragar Eagel & Squire, P.C., a nationally recognized stoc ...

Following the launch of its innovative $WLFI Treasury strategy, ALT5 now operates across three distinct segments: its $WLFI Treasury, an established and revenue generating Fintech & Payments business, and its legacy Biotech business. With a focus on disciplined capital allocation and long-term decision-making, management believes each segment has unique value drivers and viable strategies designed to drive growth and success. $WLFI Treasury LAS VEGAS--(BUSINESS WIRE)--ALT5 Sigma Corporation (the "Company†or ...

If you are interested in keeping up to date with stocks making moves within the biotech, pharma and healthcare industries, and understanding the key trends and catalysts driving valuations ahead of the market, why not subscribe to my weekly newsletter via my Investing Group, Haggerston BioHealth ?In my last note on Altimmune, Inc. ( ALT ) back in late August, I made the bull case for its stock. I discussed the Gaithersburg, Maryland based biotech's lead and only drug candidate, pemvidutide, andEdmund Ingham ...

Summary of Altimmune Conference Call Company Overview - **Company**: Altimmune - **Industry**: Biotechnology, specifically focusing on liver diseases and metabolic disorders Key Points and Arguments Leadership Transition - Transition from Vipin to Jerry as CEO is seen as timely and strategic for Altimmune's next phase, particularly as the company approaches a large Phase 3 program [4][5][6] - Jerry's experience with Intercept and the launch of Ocaliva is expected to bring valuable commercial expertise to Altimmune [4][5] Pemvidutide Development - Pemvidutide is highlighted as a key product with potential benefits for liver disease, weight loss, and metabolic parameters [5][6] - The company is preparing for an end-of-phase two meeting with the FDA, which is scheduled and will be in-person [9][10] - Upcoming 48-week data is anticipated to provide insights into the drug's efficacy and safety [9][27] Regulatory Strategy - The company aims to align with the FDA on flexible Phase 3 design, potentially incorporating AI-based reading or non-invasive tests (NITs) as endpoints [10][12] - The use of AI is expected to reduce bias in assessments and improve the accuracy of data [13][26] Clinical Data Insights - At 24 weeks, significant results were observed, including MASH resolution without worsening fibrosis, defatting of the liver, and weight loss while preserving lean muscle mass [31][32] - The company aims to maintain or improve these results at the 48-week mark, focusing on tolerability and continued weight loss [33][34] Alcohol Use Disorder (AUD) and Alcoholic Liver Disease (ALD) - Altimmune is pursuing indications for AUD and ALD, leveraging the unique benefits of pemvidutide [42][44] - The primary endpoint for the AUD study is the reduction in heavy drinking days, with additional biomarkers being tracked [48] Market Strategy and Commercialization - Jerry emphasizes the importance of being externally focused and understanding market dynamics as the company transitions from a developmental to a commercial entity [51][52] - The strategic focus is on building and enhancing the pemvidutide program, with plans to differentiate it in the market [58] Future Outlook - The company is optimistic about the upcoming data readouts and the potential for pemvidutide to address significant unmet needs in liver diseases [46][49] - The leadership transition is expected to enhance Altimmune's capabilities and strategic direction moving forward [56][58] Additional Important Insights - The company is focused on ensuring patient retention on chronic therapies, which is critical for long-term success [32][34] - The combination of glucagon and GLP-1 in pemvidutide is seen as a promising approach for treating both MASH and AUD/ALD [42][47] - The enrollment for the AUD trial was completed ahead of schedule, indicating strong interest and potential in this indication [45]

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Jerry Durso, accomplished industry leader, to succeed Vipin Garg, Ph.D. as Chief Executive Officer Transition follows seven years of strong leadership by Dr. Garg GAITHERSBURG, Md., Dec. 01, 2025 (GLOBE NEWSWIRE) -- Altimmune, Inc. (Nasdaq: ALT), a late clinical-stage biopharmaceutical company developing novel peptide-based therapeutics for liver and metabolic diseases, today announced a CEO succession plan under which Vipin Garg, Ph.D. will step down as the Company’s President and Chief Executive Officer e ...

GAITHERSBURG, Md., Nov. 26, 2025 (GLOBE NEWSWIRE) -- Altimmune, Inc. (Nasdaq: ALT), a late clinical-stage biopharmaceutical company developing novel peptide-based therapeutics for liver and cardiometabolic diseases, today announced that members of the Company’s management team will participate in a fireside chat at the Piper Sandler 37th Annual Healthcare Conference. Details are as follows: Conference: Piper Sandler 37th Annual Healthcare ConferenceDate/Time: Wednesday, December 3, 2025 at 2:30 p.m. ET The ...