Core Insights - The recent Medicare negotiations are expected to save approximately 36% on the prices of 15 high-cost drugs, translating to around $8.5 billion in net reimbursement costs [1][3][10] - The new prices will take effect in 2027, with significant reductions for popular drugs like semaglutide, which will drop over 70% to about $274 per month [1][4] - The negotiations are part of the Inflation Reduction Act signed by President Biden in 2022, which allows Medicare to negotiate drug prices for the first time [2][11] Drug Price Reductions - The estimated net prices for drugs like Calquence, Ofev, and Ibrance have been reduced by over $4,000 each in the latest negotiations [2][4] - The new pricing for other drugs includes Trelegy Ellipta at $175 (down from $654) and Linzess at $136 (down from $539) [4][10] - The average negotiated prices for these drugs are still higher than those in the Group of Seven (G7) nations, with some drugs costing over $500 more than their G7 counterparts [7][11] Comparison with Previous Negotiations - The 36% savings in the current negotiations surpasses the 22% savings achieved in the previous year's negotiations for 10 different drugs [3][10] - The pricing strategy has become more efficient, with newer products potentially having greater flexibility in pricing [4][10] Industry Response - The pharmaceutical industry has expressed strong opposition to government price negotiations, arguing that such policies are detrimental [5][10] - Industry representatives claim that government pricing policies like the Inflation Reduction Act and the Most-Favored-Nation pricing are misguided [5][12] Future Implications - The Medicare negotiations are expected to influence other payers to seek similar pricing from drug manufacturers [10] - Future negotiations will include an additional 15 drugs, with discussions set to begin in February [12]

Group 1: NVIDIA Corp. (NVDA) - NVIDIA's shares have outperformed the Zacks Semiconductor - General industry year-to-date, with a growth of +35.9% compared to +34.2% [4] - The company is benefiting from strong growth in artificial intelligence (AI) and high-performance accelerated computing, particularly in data center revenues driven by demand for generative AI and large language models using its GPUs [4] - Collaborations with over 320 automakers and tier-one suppliers are enhancing NVIDIA's presence in the autonomous vehicle sector [5] - A limited supply of Blackwell GPUs may hinder NVIDIA's ability to meet demand, and rising production costs for complex AI systems could negatively impact margins [6] Group 2: AT&T Inc. (T) - AT&T's shares have outperformed the Zacks Wireless National industry year-to-date, with a growth of +17.6% compared to +3.7% [7] - The company is expected to benefit from a customer-centric business model and solid wireless traction, supported by an integrated fiber expansion strategy and steady 5G deployments [7] - AT&T aims to deploy Open RAN for 70% of its wireless network traffic by late 2026 and plans to pass over 50 million fiber locations by the end of 2030 [8] - The wireline division is facing challenges with persistent losses in access lines due to competitive pressures, and high debt levels remain a concern [9] Group 3: Amgen Inc. (AMGN) - Amgen's shares have outperformed the Zacks Medical - Biomedical and Genetics industry year-to-date, with a growth of +32.5% compared to +19.9% [10] - The company exceeded third-quarter estimates for both earnings and sales, driven by key medicines like Evenity, Repatha, and newer products like Tavneos and Tezspire [10] - New biosimilar launches are contributing to Amgen's top-line growth, although increased pricing pressures and competition are negatively impacting sales of several products [11] - Sales of best-selling drugs Prolia and Xgeva are expected to decline due to biosimilar competition, and recent pipeline setbacks pose additional concerns [11]

AI Pharma Website Image created with DALL·E / OpenAI.For two decades, the branded pharma website has been treated as the centerpiece of digital engagement. It has been the polished ‘front door’, where brands prepared to tell their story and hoped clinicians and patients would arrive to listen. Websites still get foot traffic, but they’ve become houses people notice as they pass by, not doors where they open, enter, and spend their precious time.Traffic still flows, but engagement is collapsing. Not because ...

Amgen Inc. (AMGN) is a leading biopharmaceutical company that discovers, develops, manufactures, and delivers human therapeutics for serious illnesses. Headquartered in Thousand Oaks, California, Amgen has a market capitalization of around $180 billion, making it one of the largest biotech firms in the world. Companies with a market cap of $10 billion or more are typically recognized as “large-cap stocks”, a classification that reflects their financial heft, robust performance, and global market presence, ...

Group 1 - The author has a background in private credit and commercial real estate (CRE) mezzanine financing, indicating expertise in financial analysis and investment strategies [1] - The author has collaborated with prominent CRE developers, suggesting a strong network and experience in the real estate sector [1] - The author is a fluent Mandarin speaker, which may provide advantages in understanding Asian markets and investment opportunities [1] Group 2 - The article expresses personal opinions and analysis, highlighting the author's independent research approach [2] - The author holds long positions in several pharmaceutical companies, indicating a focus on the healthcare sector for investment [2] - There is no business relationship with the companies mentioned, ensuring an unbiased perspective in the analysis [2]

Investment Rating - The report maintains an "Outperform" rating for the pharmaceutical industry [2] Core Insights - Eli Lilly's revenue increased by 52% year-on-year in Q3 2025, driven by GLP-1 drugs, with Tirzepatide's quarterly revenue exceeding $10 billion for the first time, showing a 131% year-on-year growth [4] - Novo Nordisk faced intensified competition in the weight loss drug market, leading to a modest revenue growth of 1% for Ozempic and 6% for Wegovy in Q3 2025, prompting a downward revision of its annual performance guidance [4] - A total of 11 out of 16 companies in the report raised their revenue and/or net profit/EPS forecasts for the year, primarily due to better-than-expected sales of new products [4] Summary by Sections 1. Q3 2025 Performance Review - Eli Lilly's Q3 revenue reached $17.6 billion, with a 62% increase in sales volume, while net prices decreased by 10% [12] - Novo Nordisk's sales revenue for Q3 was 75 billion Danish Kroner, with a net profit decline of 27% [13] - JNJ's pharmaceutical segment achieved revenue of $15.6 billion, with significant contributions from oncology and neurology products [14] - AbbVie reported global sales of $15.8 billion, with notable growth in immunology and neurology sectors [15] - Gilead's revenue for Q3 was $7.3 billion, with a 4% increase in HIV product sales [16] 2. MNC Product Performance in the U.S. Market - The median time for MNC products to reach peak sales in the U.S. market is approximately 8 years, with first-in-class (FIC) products achieving this in about 7 years [4] 3. Revenue and Guidance Adjustments - Eli Lilly raised its full-year revenue guidance from $60-62 billion to $63-63.5 billion [12] - Novo Nordisk revised its revenue growth forecast down from 8%-14% to 8%-11% [13] - JNJ increased its full-year revenue guidance from $93.2-93.6 billion to $93.5-93.9 billion [14]

Underscores IMDELLTRA as a Recognized Standard of Care Treatment for Patients With Extensive Stage Small Cell Lung Cancer That Has Progressed Accessibility StatementSkip Navigation Global Confirmatory Phase 3 DeLLphi-304 Trial Showed IMDELLTRA Reduced Risk of Death by 40% Compared to Chemotherapy THOUSAND OAKS, Calif., Nov. 19, 2025 /PRNewswire/ -- Amgen (NASDAQ: AMGN) announced today that the U.S. Food and Drug Administration (FDA) has granted full approval to IMDELLTRA (tarlatamab-dlle) for the treatment ...

Core Viewpoint - The pharmaceutical sector, particularly companies like Eli Lilly and Amgen, has seen significant stock price increases, driven by a shift in investor focus from AI-related stocks to more stable growth stocks in healthcare [2][3][4]. Group 1: Market Trends - The S&P 500 index reached a historical high on October 28, with Eli Lilly's stock rising by 25% and Amgen's by 17% [2]. - AI-related stocks, such as Oracle and Meta, have experienced significant declines, with Oracle down 22% and Meta down 20% [3]. - Investors are reallocating funds from large-cap tech stocks to defensive sectors like healthcare, which are perceived as offering stable growth [3][4]. Group 2: Policy Impact - Concerns over potential drug price reductions under the Trump administration had previously suppressed healthcare stocks, but these fears have begun to ease [4][5]. - A recent agreement between Pfizer and the U.S. government to control drug prices has shifted market perceptions, leading to a more favorable outlook for pharmaceutical companies [4][5]. Group 3: Company Performance - Eli Lilly reported strong earnings for Q3 2025, with its diabetes drug Mounjaro and obesity drug Zepbound exceeding market expectations [5]. - Other companies like Merck and Amgen also reported earnings surpassing market forecasts, contributing to rising stock prices [5]. - Analysts, including Morgan Stanley's Michael Wilson, have a positive outlook on healthcare stocks due to earnings growth, reduced policy uncertainty, and low valuations [5].

美国制药企业礼来的业绩好（Reuters） 以标普500指数创下历史新高的10月28日为起点观察近期涨跌幅，涨幅靠前的多为医疗保健类，如涨幅 第一的礼来公司（上涨25%）、第二的安进公司（上涨17%）。跌幅靠前的则是AI相关股票。有报告预 测2026年医药板块将走强…… 在美国股市中，医药品等医疗保健类股票的上涨开始显著。受人工智能（AI）概念股行情转弱影响， 投资者正把资金从此前涨幅较大的板块转向股价相对滞后的稳定增长型股票。由于担心特朗普政府推行 药价下调政策导致业绩恶化的忧虑也有所减退，这一因素也很重要。以防御为重心的板块轮换，正左右 整个市场的走向。 尽管投资者已经意识到由AI股引发的调整风险，但他们并没有选择从股市撤资，因为美国企业整体业 绩仍普遍良好。在重新审视投资组合的资产配置过程中，"此前不在投资者视线中的"（日生资产管理高 级运用部长三国公靖）医疗保健股开始浮现。 以标普500指数创下历史新高的10月28日为起点观察近期涨跌幅，涨幅靠前的多为医疗保健类，例如涨 幅第一的礼来公司（上涨25%）、第二的安进公司（上涨17%）。医药股是被视为可期待稳定增长 的"防御性股票"的典型代表。自年初以来带 ...

We recently published 8 Stocks Jim Cramer Discussed & Mentioned An Important Quantum Computing Development. Amgen Inc. (NASDAQ:AMGN) is one of the stocks Jim Cramer discussed. Cramer has recently started to discuss pharmaceutical giant Amgen Inc. (NASDAQ:AMGN) more frequently. Most of his discussions surround the firm’s Repatha drug that aims to reduce cholesterol and prevent adverse cardiovascular events. In a November 11th appearance, the CNBC TV host commented that Amgen Inc. (NASDAQ:AMGN), along with ...