Core Insights - BeyondSpring Pharmaceuticals (BYSI) experienced a stock price increase of 2.9%, reaching $1.77 per share, with a total market capitalization of $71.38 million as of August 22 [1] - For the fiscal year ending June 30, 2024, the company reported total revenue of $1.00 million, reflecting a year-over-year growth of 14.29%, while the net profit attributable to shareholders was -$7.26 million, showing a year-over-year increase of 42.91% [1] Company Overview - BeyondSpring Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing novel cancer therapies, including advanced tumor immunotherapy [2] - The company was founded in 2013 and is headquartered in the United States, with a mission to transform cancer treatment through its academic and business capabilities [2] - The primary project, Plinabulin, is derived from natural compounds and has therapeutic potential for various cancers, with a unique and scalable business model that integrates resources from the U.S. and China for efficient and low-cost drug approval and development [2] - Target research areas include non-small cell lung cancer, prevention of neutropenia, and Plinabulin combined with PD-1 monoclonal antibodies [2]

Core Insights - BeyondSpring Pharmaceuticals (BYSI) experienced a stock price increase of 5.19%, reaching $1.841 per share with a total market capitalization of $74.24 million as of August 20 [1] - For the fiscal year ending June 30, 2024, the company reported total revenue of $1 million, reflecting a year-over-year growth of 14.29%, while the net profit attributable to shareholders was -$7.262 million, showing a 42.91% increase in losses compared to the previous year [1] Company Overview - BeyondSpring is a clinical-stage biopharmaceutical company focused on developing novel cancer therapies, including advanced tumor immunotherapy [1] - The company was founded in 2013 and is headquartered in the United States, aiming to transform cancer treatment through its academic and business capabilities [1] - The primary project, Plinabulin, is derived from natural compounds and has therapeutic potential for various cancers due to its biochemical activities [1] Business Model and Research Focus - BeyondSpring employs a novel, highly scalable business model that integrates resources from both the U.S. and China to efficiently and cost-effectively achieve drug approval and development [1] - The target research areas include non-small cell lung cancer, prevention of neutropenia, and the combination of Plinabulin with PD-1 monoclonal antibodies [1]

[Forward-Looking Statements](index=4&type=section&id=FORWARD-LOOKING%20STATEMENTS) [Forward-Looking Statements](index=4&type=section&id=FORWARD-LOOKING%20STATEMENTS) This section cautions investors that forward-looking statements involve risks and uncertainties, and actual results may differ - The report identifies numerous forward-looking statements concerning the company's operations, including clinical trial progress, regulatory filings, commercialization potential, financial projections, and intellectual property strategy[12](index=12&type=chunk)[16](index=16&type=chunk) - Investors are directed to "Part II, Item 1A. Risk Factors" for a detailed discussion of risks that could cause actual results to differ from those projected in the forward-looking statements[11](index=11&type=chunk)[13](index=13&type=chunk) [PART I. FINANCIAL INFORMATION](index=6&type=section&id=PART%20I.%20FINANCIAL%20INFORMATION) [Financial Statements](index=6&type=section&id=Item%201.%20Financial%20Statements) Unaudited Q2 2025 financial statements report a net loss of $4.6 million, reclassifying SEED Therapeutics as a discontinued operation [Condensed Consolidated Balance Sheets](index=6&type=section&id=Condensed%20Consolidated%20Balance%20Sheets) As of June 30, 2025, total assets decreased to **$31.0 million**, while cash from continuing operations increased to **$9.5 million** Condensed Consolidated Balance Sheet Highlights (in thousands of U.S. Dollars) | Account | Dec 31, 2024 | June 30, 2025 (Unaudited) | | :--- | :--- | :--- | | **Assets** | | | | Cash and cash equivalents | $2,922 | $9,544 | | Current assets of discontinued operations | $25,347 | $15,712 | | Total assets | $34,315 | $31,043 | | **Liabilities & Equity** | | | | Total current liabilities | $11,010 | $11,730 | | Total liabilities | $48,600 | $48,588 | | Total shareholders' deficit | ($14,285) | ($17,545) | [Condensed Consolidated Statements of Comprehensive Income (Loss)](index=8&type=section&id=Condensed%20Consolidated%20Statements%20of%20Comprehensive%20Income%20(Loss)) For H1 2025, net loss from continuing operations was **$4.5 million**, but a **$7.0 million** gain from subsidiary sale resulted in a total net income of **$2.7 million** Six Months Ended June 30, (in thousands of U.S. Dollars) | Metric | 2024 | 2025 | | :--- | :--- | :--- | | Revenue | $0 | $0 | | Research and development | ($1,550) | ($1,876) | | General and administrative | ($3,146) | ($2,683) | | Net loss from continuing operations | ($4,731) | ($4,462) | | Net income (loss) from discontinued operations | ($2,646) | $983 | | Net income (loss) attributable to BeyondSpring Inc. | ($7,262) | $2,671 | | Basic and diluted EPS | ($0.19) | $0.07 | [Condensed Consolidated Statements of Cash Flows](index=12&type=section&id=Condensed%20Consolidated%20Statements%20of%20Cash%20Flows) For H1 2025, net cash used in operating activities was **$10.1 million**, offset by **$17.2 million** from investing activities, resulting in a net cash increase of **$7.1 million** Cash Flow Summary for Six Months Ended June 30, (in thousands of U.S. Dollars) | Cash Flow Activity | 2024 | 2025 | | :--- | :--- | :--- | | Net cash used in operating activities | ($12,254) | ($10,072) | | Net cash provided by investing activities | $0 | $17,154 | | Net cash provided by financing activities | $3,000 | $0 | | Net increase (decrease) in cash | ($9,354) | $7,080 | [Notes to Condensed Consolidated Financial Statements](index=13&type=section&id=Notes%20to%20Condensed%20Consolidated%20Financial%20Statements) Key notes detail the divestiture of SEED Therapeutics as a discontinued operation, collaboration agreements, and the company's deferred tax asset valuation allowance - The company approved a plan to sell 90-100% of its interest in SEED Therapeutics. The first closing occurred in February 2025 for **$7.35 million**, resulting in a recognized gain of **$7.0 million**. The company's ownership in SEED decreased to **40.12%** but it retained control[62](index=62&type=chunk)[68](index=68&type=chunk)[70](index=70&type=chunk) - The collaboration with Hengrui for Plinabulin in Greater China involves an upfront fee of **$31.0 million** (RMB 200 million) and potential milestones. No revenue has been recognized from this agreement as of June 30, 2025, and the upfront fee is recorded as deferred revenue[71](index=71&type=chunk)[72](index=72&type=chunk)[74](index=74&type=chunk) - The collaboration with Eli Lilly via subsidiary SEED involves an upfront fee of **$10 million** and potential milestones up to **$780 million**. Revenue from this agreement is recognized over time and is reported within discontinued operations[76](index=76&type=chunk)[77](index=77&type=chunk)[81](index=81&type=chunk) - As of June 30, 2025, the company maintained a full valuation allowance against its net deferred tax assets, believing it is more likely than not that they will not be realized[87](index=87&type=chunk) [Management's Discussion and Analysis of Financial Condition and Results of Operations (MD&A)](index=33&type=section&id=Item%202.%20Management's%20Discussion%20and%20Analysis%20of%20Financial%20Condition%20and%20Results%20of%20Operations) Management discusses Plinabulin development, SEED Therapeutics divestiture, and H1 2025 financial results, noting decreased G&A and increased R&D expenses - The company's lead asset, Plinabulin, is being developed as an anti-cancer agent, with a focus on non-small cell lung cancer (NSCLC) patients who have progressed on checkpoint inhibitors. The company plans to file a New Drug Application (NDA) with China's NMPA[122](index=122&type=chunk)[124](index=124&type=chunk) - The company entered into agreements to sell a portion of its SEED preferred shares for **$35.4 million** in three tranches. The first closing in February 2025 yielded **$7.35 million**. Future closings are expected by December 2025 and December 2026[134](index=134&type=chunk) - As of June 30, 2025, continuing operations held **$9.5 million** in cash and cash equivalents. Management anticipates that current financial resources will be sufficient to meet operational expenses for the next 12 months[130](index=130&type=chunk)[161](index=161&type=chunk) [Results of Operations](index=38&type=section&id=Results%20of%20Operations) For H1 2025, R&D expenses increased by **21%** to **$1.9 million**, while G&A expenses decreased by **15%** to **$2.7 million**, improving net loss from continuing operations Comparison of Operating Results for the Six Months Ended June 30, (in thousands of U.S. Dollars) | Item | 2024 | 2025 | Change % | | :--- | :--- | :--- | :--- | | Research and development | ($1,550) | ($1,876) | 21% | | General and administrative | ($3,146) | ($2,683) | -15% | | Loss from operations | ($4,696) | ($4,559) | -3% | | Net loss from continuing operations | ($4,731) | ($4,462) | -6% | - The **$0.3 million** increase in R&D expenses for H1 2025 was primarily due to higher professional service fees for regulatory and CMC activities and increased research on Plinabulin combination therapies[155](index=155&type=chunk) - The **$0.4 million** decrease in G&A expenses for H1 2025 was mainly due to lower salary expenses from reduced administrative headcount and lower investor relations and D&O insurance costs[157](index=157&type=chunk) [Liquidity and Capital Resources](index=41&type=section&id=Liquidity%20and%20Capital%20Resources) Liquidity improved in H1 2025, with cash from continuing operations reaching **$9.5 million** due to the SEED equity sale, and current resources are sufficient for the next 12 months - The company financed operations through a combination of equity offerings, loans, sale of subsidiary interests, and collaboration arrangements. In February 2025, it received **$7.4 million** from the first closing of the SEED sale[160](index=160&type=chunk) - Net cash used in operating activities decreased to **$10.1 million** in H1 2025 from **$12.3 million** in H1 2024[160](index=160&type=chunk)[162](index=162&type=chunk) - Management is evaluating various financing alternatives for medium to long-term funding, including equity/debt financing, licensing, partnerships, or other strategic transactions[161](index=161&type=chunk) [Quantitative and Qualitative Disclosures About Market Risk](index=45&type=section&id=Item%203.%20Quantitative%20and%20Qualitative%20Disclosures%20About%20Market%20Risk) As a smaller reporting company, BeyondSpring Inc. is exempt from providing quantitative and qualitative disclosures about market risk - The company is exempt from providing quantitative and qualitative disclosures about market risk because it qualifies as a smaller reporting company under Exchange Act Rule 12b-2[181](index=181&type=chunk) [Controls and Procedures](index=45&type=section&id=Item%204.%20Controls%20and%20Procedures) Management concluded that disclosure controls and procedures were effective as of June 30, 2025, with no material changes to internal control over financial reporting - Based on an evaluation as of June 30, 2025, the Principal Executive and Financial Officer concluded that the company's disclosure controls and procedures were effective[182](index=182&type=chunk) - No changes in internal control over financial reporting occurred during the quarter that materially affected, or are reasonably likely to materially affect, these controls[184](index=184&type=chunk) [PART II. OTHER INFORMATION](index=46&type=section&id=PART%20II.%20OTHER%20INFORMATION) [Legal Proceedings](index=46&type=section&id=Item%201.%20Legal%20Proceedings) The company is not currently a party to any legal proceedings that would materially adversely affect its business or financial condition - As of the filing date, the company is not involved in any material legal proceedings[186](index=186&type=chunk) [Risk Factors](index=46&type=section&id=Item%201A.%20Risk%20Factors) There are no material changes to the risk factors previously disclosed in the company's 2024 Annual Report on Form 10-K - The company states there are no material changes from the risk factors disclosed in its 2024 Annual Report on Form 10-K[187](index=187&type=chunk) [Exhibits](index=47&type=section&id=Item%206.%20Exhibits) This section lists the exhibits filed with the Form 10-Q, primarily including officer certifications and Inline XBRL data files - Exhibits filed include CEO/CFO certifications pursuant to Sections 302 and 906 of the Sarbanes-Oxley Act[192](index=192&type=chunk)

Core Insights - BeyondSpring Pharmaceuticals (BYSI) experienced a stock price increase of 2.24% on August 13, reaching $2.055 per share, with a total market capitalization of $82.86 million [1] - As of June 30, 2024, the company reported total revenue of $1 million, reflecting a year-over-year growth of 14.29%, while the net profit attributable to shareholders was -$7.262 million, showing a 42.91% increase in losses compared to the previous year [1] Company Overview - BeyondSpring is a clinical-stage biopharmaceutical company focused on developing novel cancer therapies, including advanced tumor immunotherapy [2] - The company was founded in 2013 and is headquartered in the United States, with a mission to transform cancer treatment through unique academic and business capabilities [2] - The primary project, Plinabulin, is derived from natural compounds and has therapeutic potential for various cancers due to its biochemical activities [2] - BeyondSpring employs an innovative and highly scalable business model that integrates resources from both the U.S. and China to efficiently and cost-effectively achieve drug approval and development [2] - Target research areas include non-small cell lung cancer, prevention of neutropenia, and the combination of Plinabulin with PD-1 monoclonal antibodies [2]

[Corporate and Clinical Highlights](index=1&type=section&id=Corporate%20and%20Clinical%20Highlights) BeyondSpring reported significant clinical progress for Plinabulin in NSCLC and SEED Therapeutics achieved FDA IND clearance for ST-01156 [CEO's Statement](index=1&type=section&id=CEO%27s%20Statement) CEO Dr. Lan Huang emphasized Plinabulin's immune-modulating potential and SEED Therapeutics' ST-01156 FDA IND clearance - Plinabulin is positioned as a first-in-class agent that harnesses the body's immune system by maturing dendritic cells, bridging innate and adaptive immunity[3](index=3&type=chunk) - The combination of plinabulin and docetaxel has shown durable survival benefits and reduced chemotherapy-induced neutropenia in a global Phase 3 trial[3](index=3&type=chunk) - SEED Therapeutics' oral RBM39 molecular glue degrader, ST-01156, received FDA clearance to enter clinical trials for aggressive cancers like Ewing Sarcoma and KRAS-driven tumors[3](index=3&type=chunk) [Key Milestones](index=1&type=section&id=Key%20Milestones) Key milestones include Plinabulin's ASCO 2025 presentation, 'Med' publication, SEED Therapeutics' ST-01156 FDA IND clearance, and new leadership - ASCO 2025 presentation highlighted Plinabulin's ability to drive immune re-sensitization in NSCLC patients who have progressed on PD-1/L1 therapies[5](index=5&type=chunk) - A publication in 'Med' (Cell Press) detailed Plinabulin's rapid activation of dendritic cells in patients across eight cancer types who had failed prior immunotherapy[5](index=5&type=chunk) - SEED Therapeutics' lead asset, RBM39 degrader ST-01156, received FDA IND clearance and is advancing toward Phase 1 trials[5](index=5&type=chunk) - Dr. Bill Desmarais was appointed as the new CFO and CBO of SEED Therapeutics to accelerate development[5](index=5&type=chunk) [Plinabulin Clinical Updates](index=1&type=section&id=Plinabulin%20Clinical%20Updates) Plinabulin's Phase 2 NSCLC study showed encouraging efficacy, and a publication with MD Anderson confirmed its dendritic cell maturation mechanism Plinabulin Phase 2 NSCLC Study Efficacy Data (ASCO 2025) | Metric | Result | | :--- | :--- | | Median Progression-Free Survival (PFS) | 6.8 months | | Confirmed Objective Response Rate (ORR) | 18.2% | | Duration of Response (DOR) | 7.2 months | | Disease Control Rate (DCR) | 77% | | Overall Survival (OS) at 15 months | 78% | - A study with MD Anderson showed Plinabulin, combined with radiation and a checkpoint inhibitor, rapidly induces dendritic cell maturation in patients who failed prior immunotherapy[6](index=6&type=chunk) - In the MD Anderson study across eight cancer types, the combination therapy achieved an Objective Response Rate (ORR) of **23%** and a Disease Control Rate (DCR) of **54%**[6](index=6&type=chunk) [SEED Therapeutics Updates](index=1&type=section&id=SEED%20Therapeutics%20Updates) SEED Therapeutics achieved FDA IND clearance for ST-01156, showing complete tumor regression in preclinical models, and appointed new leadership - The FDA cleared the IND application for ST-01156, a brain-penetrant, novel orally administered molecular glue degrader targeting RBM39[6](index=6&type=chunk)[7](index=7&type=chunk) - Preclinical data presented at AACR 2025 showed ST-01156 demonstrated complete tumor regression in Ewing Sarcoma models[9](index=9&type=chunk) - Dr. Bill Desmarais, Ph.D., MBA, joined SEED Therapeutics as CFO and Chief Business Officer, bringing over two decades of biopharma leadership experience[9](index=9&type=chunk) [Financial Performance](index=2&type=section&id=Financial%20Performance) BeyondSpring reported a reduced Q2 2025 net loss from continuing operations, improved cash, and reclassified SEED Therapeutics as discontinued operations [Q2 2025 Financial Results Summary](index=2&type=section&id=Q2%202025%20Financial%20Results%20Summary) Q2 2025 saw increased R&D, reduced G&A, a lower net loss, and a strengthened cash position for continuing operations Q2 Financial Highlights (Continuing Operations) | Metric | Q2 2025 | Q2 2024 | | :--- | :--- | :--- | | R&D Expenses | $1.0 million | $0.8 million | | G&A Expenses | $0.9 million | $1.8 million | | Net Loss | $1.9 million | $2.7 million | Cash Position | Metric | June 30, 2025 | Dec 31, 2024 | | :--- | :--- | :--- | | Cash and cash equivalents | $9.5 million | $2.9 million | [Year-to-Date 2025 Financial Results Summary](index=2&type=section&id=Year-to-Date%202025%20Financial%20Results%20Summary) Year-to-date 2025 showed a slightly improved net loss from continuing operations and a total net income including discontinued operations Six-Month Financial Highlights (Continuing Operations) | Metric | Six Months Ended June 30, 2025 | Six Months Ended June 30, 2024 | | :--- | :--- | :--- | | R&D Expenses | $1.9 million | $1.6 million | | G&A Expenses | $2.7 million | $3.1 million | | Net Loss | $4.5 million | $4.7 million | - Net income from discontinued operations was **$1.0 million** for the first six months of 2025, compared to a net loss of **$2.6 million** for the same period in 2024[8](index=8&type=chunk) [Accounting for SEED Therapeutics](index=2&type=section&id=Accounting%20for%20SEED%20Therapeutics) BeyondSpring reclassified SEED Therapeutics' financial results as discontinued operations after agreements to reduce its ownership stake - SEED Therapeutics' financial results are now reported as discontinued operations under ASC 205-20[9](index=9&type=chunk) - BeyondSpring's ownership in SEED is set to be reduced from approximately **40%** to **14%** upon completion of future sale transactions[10](index=10&type=chunk) [Condensed Consolidated Balance Sheets](index=3&type=section&id=Condensed%20Consolidated%20Balance%20Sheets) As of June 30, 2025, BeyondSpring's balance sheet showed increased cash, stable assets and liabilities, and a widened shareholders' deficit Selected Balance Sheet Data (in thousands) | Balance Sheet Item | June 30, 2025 | Dec 31, 2024 | | :--- | :--- | :--- | | Cash and cash equivalents | $9,544 | $2,922 | | Total assets | $31,043 | $34,315 | | Total liabilities | $48,588 | $48,600 | | Total shareholders' deficit | ($17,545) | ($14,285) | [Condensed Consolidated Statements of Comprehensive Income (Loss)](index=4&type=section&id=Condensed%20Consolidated%20Statements%20of%20Comprehensive%20Income%20%28Loss%29) Q2 2025 showed no revenue and a net loss from continuing operations, with year-to-date results including net income from discontinued operations Income Statement Summary (in thousands, except per share data) | Metric | Q2 2025 | Q2 2024 | Six Months 2025 | Six Months 2024 | | :--- | :--- | :--- | :--- | :--- | | Revenue | $0 | $0 | $0 | $0 | | Loss from operations | ($1,949) | ($2,641) | ($4,559) | ($4,696) | | Net loss from continuing ops | ($1,878) | ($2,651) | ($4,462) | ($4,731) | | Net income (loss) from discontinued ops | ($2,771) | ($1,438) | $983 | ($2,646) | | EPS (Continuing ops) | ($0.04) | ($0.07) | ($0.11) | ($0.12) | [Company Overview](index=3&type=section&id=Company%20Overview) BeyondSpring is a clinical-stage biopharmaceutical company developing first-in-class therapies, featuring Plinabulin and affiliate SEED Therapeutics [About BeyondSpring](index=3&type=section&id=About%20BeyondSpring) BeyondSpring is a clinical-stage biopharmaceutical company focused on developing Plinabulin, a late-stage anti-cancer agent for NSCLC - The company's lead asset, Plinabulin, is in late-stage clinical development as an anti-cancer agent in NSCLC[11](index=11&type=chunk) - Plinabulin's novel mechanism as a dendritic cell maturation agent offers a unique approach to resensitizing tumors resistant to checkpoint inhibitors[11](index=11&type=chunk) [About SEED Therapeutics](index=3&type=section&id=About%20SEED%20Therapeutics) SEED Therapeutics specializes in targeted protein degradation via its RITE3™ platform, developing a pipeline with strategic partners - SEED Therapeutics pioneers targeted protein degradation through its proprietary RITE3™ platform[12](index=12&type=chunk) - The company has strategic collaborations with major pharmaceutical companies Eli Lilly and Eisai[12](index=12&type=chunk) - SEED's lead RBM39 degrader program has received US FDA IND clearance[12](index=12&type=chunk) [Cautionary Note Regarding Forward-Looking Statements](index=3&type=section&id=Cautionary%20Note%20Regarding%20Forward-Looking%20Statements) This section warns that forward-looking statements are subject to significant risks and uncertainties, which could cause actual results to differ - The press release contains forward-looking statements that are not historical facts and are based on current knowledge, beliefs, and expectations[13](index=13&type=chunk) - Actual results could differ materially due to risks such as difficulties in raising capital, unexpected clinical trial results, regulatory delays, and market competition[13](index=13&type=chunk)

Core Insights - BeyondSpring Inc. reported Q2 2025 financial results and highlighted significant clinical and corporate milestones, focusing on its lead asset, Plinabulin, which is positioned to redefine cancer treatment by leveraging the immune system [1][2]. Clinical Developments - Plinabulin is a first-in-class agent that matures dendritic cells, potentially offering new hope to 60% of non-small cell lung cancer (NSCLC) patients whose disease progresses after checkpoint inhibitor therapy [2]. - In the global Phase 3 trial (Dublin-3), the combination of Plinabulin and docetaxel showed durable survival benefits and reduced chemotherapy-induced neutropenia compared to standard docetaxel alone [2]. - New data from a Phase 2 study indicated that the combination of pembrolizumab, Plinabulin, and docetaxel in metastatic NSCLC patients demonstrated a median progression-free survival (PFS) of 6.8 months and an overall survival (OS) of 78% at 15 months [5]. - A collaboration with MD Anderson highlighted Plinabulin's rapid dendritic cell activation across eight cancer types, reporting an objective response rate (ORR) of 23% and a disease control rate (DCR) of 54% [5]. Corporate Milestones - SEED Therapeutics, in which BeyondSpring is a founding shareholder, received FDA clearance for its RBM39 molecular glue degrader, ST-01156, targeting aggressive cancers [2][4]. - Dr. Bill Desmarais joined SEED Therapeutics as CFO and CBO, bringing over 20 years of biotech leadership experience [6]. Financial Performance - For the six months ended June 2025, BeyondSpring reported a net income of $1 million, an improvement from a net loss of $2.6 million in the same period of 2024 [7]. - Research and development (R&D) expenses increased to $1.9 million for the six months ended June 2025, compared to $1.6 million in the prior year, primarily due to higher professional service fees [9]. - General and administrative (G&A) expenses decreased to $2.7 million for the six months ended June 2025, down from $3.1 million in the same period of 2024 [9]. Financial Position - As of June 30, 2025, cash and cash equivalents stood at $9.5 million, a significant increase from $2.9 million as of December 2024 [9]. - Current assets totaled $15.7 million, down from $25.3 million as of December 2024, reflecting the impact of discontinued operations [9].

Core Insights - BeyondSpring Pharmaceuticals (BYSI) opened with a 2.5% increase, reaching $2.05 per share, with a total market capitalization of $82.66 million as of 21:30 [1] - For the fiscal year ending June 30, 2024, the company reported total revenue of $1.00 million, reflecting a year-over-year growth of 14.29%, while the net profit attributable to shareholders was -$7.26 million, showing a 42.91% increase in losses compared to the previous year [1] Company Overview - BeyondSpring is a clinical-stage biopharmaceutical company focused on developing novel cancer therapies, including advanced tumor immunotherapy [1] - The company was founded in 2013 and is headquartered in the United States, with a mission to transform cancer treatment through its academic and business capabilities [1] - The primary project, Plinabulin, is derived from natural compounds and has therapeutic potential for various cancers, targeting areas such as non-small cell lung cancer and the prevention of neutropenia [1] Business Model and Strategy - BeyondSpring employs a novel, highly scalable business model that integrates resources from both the U.S. and China to efficiently and cost-effectively achieve drug approval and development [1] - The company's research focus includes Plinabulin in combination with PD-1 monoclonal antibodies [1]

Core Insights - BeyondSpring Pharmaceuticals (BYSI) experienced a stock price increase of 3.19% on August 8, reaching $2.105 per share, with a total market capitalization of $84.8785 million [1] - As of June 30, 2024, the company reported total revenue of $1 million, reflecting a year-over-year growth of 14.29%, while the net profit attributable to shareholders was -$7.262 million, showing a 42.91% increase in losses compared to the previous year [1] - The company is focused on developing novel cancer therapies, particularly advanced tumor immunotherapy, and aims to transform cancer treatment through its unique academic and business capabilities [1] Financial Performance - Total revenue for the fiscal year ending June 30, 2024, is projected at $1 million, marking a 14.29% increase year-over-year [1] - The net profit attributable to shareholders is reported at -$7.262 million, which is a 42.91% increase in losses compared to the previous year [1] Company Overview - BeyondSpring Pharmaceuticals is a clinical-stage biopharmaceutical company established in 2013, headquartered in the United States [1] - The company specializes in the research and development of new cancer therapies, including treatments for non-small cell lung cancer and the prevention of neutropenia [1] - The main project, Plinabulin, is derived from natural compounds and has therapeutic potential for various cancers [1] - BeyondSpring employs a novel, highly scalable business model that integrates resources from the U.S. and China to efficiently and cost-effectively achieve drug approval and development [1]

Group 1 - The stock price of BeyondSpring Inc. (BYSI) increased by 5.07% on August 6, reaching $2.154 per share, with a total market capitalization of $86.8373 million [1] - As of June 30, 2024, BeyondSpring reported total revenue of $1.0 million, reflecting a year-over-year growth of 14.29%, while the net profit attributable to shareholders was -$7.262 million, showing a year-over-year increase of 42.91% [1] Group 2 - BeyondSpring is a clinical-stage biopharmaceutical company focused on developing novel cancer therapies, including advanced tumor immunotherapy [2] - The company was founded in 2013 and is headquartered in the United States, with a mission to transform cancer treatment through its academic and business capabilities [2] - The main project, Plinabulin, is derived from natural compounds and has therapeutic potential for various cancers, with a novel, scalable business model aimed at efficient and low-cost drug approval and development [2] - Target research areas include non-small cell lung cancer, prevention of neutropenia, and Plinabulin combined with PD-1 monoclonal antibodies [2]

Core Insights - BeyondSpring Pharmaceuticals (BYSI) experienced a stock price increase of 3.41% on August 6, reaching $2.12 per share, with a total market capitalization of $85.47 million [1] - As of June 30, 2024, the company reported total revenue of $1.00 million, reflecting a year-over-year growth of 14.29%, while the net profit attributable to shareholders was -$7.26 million, showing a 42.91% increase in losses compared to the previous year [1] - The company is set to disclose its fiscal year 2024 annual report on May 5, with the actual release date subject to company announcements [1] Company Overview - BeyondSpring Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing novel cancer therapies, including advanced tumor immunotherapy [1] - Founded in 2013 and headquartered in the United States, the company aims to leverage its academic and business expertise in cancer treatment to transform the current landscape of cancer therapy [1] - The primary project, Plinabulin, is derived from natural compounds and has therapeutic potential for various cancers due to its biochemical activities [1] Business Model and Research Focus - The company employs an innovative and highly scalable business model that integrates resources from both the U.S. and China to efficiently and cost-effectively achieve drug approval and development [1] - Key research areas include non-small cell lung cancer, prevention of neutropenia, and the combination of Plinabulin with PD-1 monoclonal antibodies [1]