CONSHOHOCKEN, Pa., Jan. 21, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL), a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), today announced that it granted an equity award on January 15, 2026 to Rita Thakkar, the company’s new Chief Accounting Officer, as an equity inducement award under the terms of Madrigal’s 2025 Inducement Plan. The equity award was approved by Madrigal’s Board of Directors in accord ...

Goldman Sachs analyst Andrea Tan sets a price target of $571 for NASDAQ:MDGL, indicating a potential upside of 15.61%.Madrigal Pharmaceuticals participates in the 44th Annual J.P. Morgan Healthcare Conference, potentially influencing its stock performance.The company's stock has experienced significant fluctuations over the past year, with a high of $615 and a low of $265.Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) is a biopharmaceutical company focused on developing innovative therapies for cardiovascular ...

Goldman Sachs reiterates a "Buy" rating for Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL), indicating confidence in the company's growth potential.The stock price of Madrigal Pharmaceuticals experienced a decrease of 3.26%, showing market volatility.Madrigal's presentation at the 44th Annual J.P. Morgan Healthcare Conference highlights its strategic direction and developments in the NASH space.Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) is a biopharmaceutical company focused on developing innovative therapi ...

Core Viewpoint - Madrigal Pharmaceuticals is positioned as a leading company in the metabolic and liver disease sector, with significant accomplishments over the past two years and a strong outlook for the future [2][3]. Company Overview - Madrigal Pharmaceuticals has been recognized as one of the most consequential companies in the metabolic and liver disease space in recent years [2]. - The company is led by CEO Bill Sibold, CMO Dr. David Soergel, and CFO Mardi Dier, who are actively engaging with stakeholders to provide updates on the company's progress [2]. Strategic Focus - The company's primary mission is to lead the fight against MASH (Metabolic Associated Steatotic Hepatitis), which reflects its commitment to addressing critical health challenges in this area [4]. - Madrigal emphasizes the importance of leadership and innovation in its approach to tackling MASH, aiming to differentiate itself within the industry [4].

Core Viewpoint - A U.S. judge has allowed Orsted to resume work on the nearly finished Revolution Wind project, leading to a nearly 6% rise in the company's shares [1]. Group 1: Project Overview - The Revolution Wind project is a $5 billion initiative located about 15 miles south of the Rhode Island coast, developed as a 50/50 joint venture between Orsted and Global Infrastructure Partners' Skyborn Renewables [2]. - Orsted and Skyborn Renewables have reported that they have already invested approximately $5 billion into the Revolution Wind project [2]. Group 2: Legal Context - The ruling represents a legal setback for the Trump administration, which had attempted to block the Revolution Wind project [2].

Summary of Madrigal Pharmaceuticals FY Conference Call Company Overview - **Company**: Madrigal Pharmaceuticals (NasdaqGS:MDGL) - **Industry**: Metabolic and liver disease - **Key Product**: Rezdiffra, the first-ever approved product for MASH (Metabolic Associated Steatotic Hepatitis) Core Points and Arguments 1. **Market Leadership**: Madrigal is positioned as a leader in the MASH space with a successful product launch, achieving over $1 billion in annualized sales after six quarters [3][4][29]. 2. **Future Growth**: The company anticipates significant growth opportunities with the upcoming F4C indication data expected in 2027, which could potentially double the market opportunity for Rezdiffra [4][30]. 3. **Patient Base**: As of Q3 2025, over 29,500 patients are on Rezdiffra therapy, with 10,000 prescribers, indicating a strong foundation for continued growth [9][10]. 4. **Market Dynamics**: The MASH market is currently under-penetrated, with only 10% of diagnosed patients being treated. The company sees potential for expansion similar to other large specialty markets [11][12]. 5. **Pipeline Development**: Madrigal is focused on building a robust pipeline in MASH, including new mechanisms of action and combination therapies to enhance treatment efficacy [17][18][20]. Important Developments 1. **Combination Therapies**: The company is exploring combination therapies with new assets like a DGAT2 inhibitor and an oral GLP-1 molecule, which are expected to enhance the efficacy of Rezdiffra [20][25]. 2. **Clinical Trials**: Ongoing and upcoming trials include the Maestro Outcomes trial for F4C and the Maestro NASH study for F2, F3, with data expected in 2027 and 2028 respectively [17][18]. 3. **Market Access**: Madrigal has secured first-line access with no step-edit requirements, which is crucial for maintaining strong market presence against competitors [10][49]. Financial Outlook 1. **Sales Growth**: The company expects robust net revenue growth in 2026 despite anticipated changes in gross-to-net dynamics due to commercial contracting [49][50]. 2. **Profitability Timeline**: While profitability is not the immediate focus, the company is confident in achieving it as top-line growth outpaces spending [45][46]. Additional Insights 1. **Global Expansion**: Madrigal has launched in Germany and is exploring opportunities in other countries, particularly in the Middle East, but does not expect significant contributions from international sales in 2026 [55][56]. 2. **Competitive Landscape**: The company acknowledges the presence of competitors but believes that the unique profile of Rezdiffra and its established market access will allow it to thrive [10][53]. Conclusion Madrigal Pharmaceuticals is strategically positioned to lead the MASH market with its innovative product Rezdiffra and a growing pipeline. The company is focused on maximizing its market potential through combination therapies and expanding its patient base while maintaining a strong financial outlook for the coming years [28][30].

This presentation includes "forward-looking statements" made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, that are based on Madrigal's beliefs and assumptions and on information currently available to it but are subject to factors beyond its control. Forward-looking statements reflect management's current knowledge, assumptions, judgment and expectations regarding future performance or events. Forward-looking statements include all statements that are not h ...

Key Takeaways Madrigal has licensed global rights to ervogastat to build combination therapies for MASH.Ervogastat cut liver fat in a phase II study, with up to 72% patients hitting a 30% reduction on MRI-PDFF.MDGL eyes drug-to-drug interaction work with Rezdiffra, and FDA talks ahead of a phase II combination study.Madrigal Pharmaceuticals (MDGL) has acquired exclusive global rights to ervogastat from Pfizer (PFE) , strengthening its pipeline of innovative and combination therapies for metabolic dysfunctio ...

Agreement expands Madrigal’s pipeline and strengthens its leadership in pioneering MASH therapiesDGAT-2 inhibition represents a complementary mechanism of action with Rezdiffra® (resmetirom) for potential additive therapeutic benefit in MASHMadrigal to present at the 44th Annual J.P. Morgan Healthcare Conference at 1:30 p.m. PST (4:30 p.m. EST) on Monday, January 12, 2026 CONSHOHOCKEN, Pa., Jan. 09, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ: MDGL), a biopharmaceutical company focused o ...

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