CONSHOHOCKEN, Pa., Oct. 22, 2025 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ: MDGL), a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), announced today that it will release its third-quarter 2025 financial results on Tuesday, Nov. 4, 2025, prior to the open of the U.S. financial markets. Following the announcement, Madrigal’s management will host a live webcast at 8 a.m. Eastern Time to review the Company’s financi ...

Pharma companies are betting big on drugs that treat MASH, a serious liver disease linked to obesity and metabolic issues. Several companies have snapped up experimental drugs this year, including Roach and Novon Nordisk, which uh each have agreed to acquire liver disease focused companies and deals potentially worth several billion dollars a piece. The moves follow successful launch of Magical's drug res, which was the first match drug cleared by the FDA back in March 2024.For more in the increasingly comp ...

CONSHOHOCKEN, Pa., Oct. 07, 2025 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL), a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), today announced that it granted equity awards on October 1, 2025 to 27 new non-executive employees as equity inducement awards under the terms of Madrigal's 2025 Inducement Plan. The equity awards were approved by Madrigal's independent Compensation Committee in accordance with Nasd ...

Group 1 - Mergers and acquisitions (M&A) activity has increased significantly in 2025, with a 29% rise in deal value year-over-year and an 8% increase in the number of deals [3][4] - Electronic Arts is set to be taken private in the largest leveraged buyout ever, resulting in a stock price increase of over 20% in two days following the announcement [1] - Goldman Sachs predicts a further 15% growth in the number of M&A deals in 2026, driven by improving economic conditions and CEO confidence [4] Group 2 - A basket of potential M&A candidates has outperformed the S&P 1500 by seven percentage points since early September [2] - Goldman Sachs has identified six stocks with a 30% to 50% chance of being acquired in the next 12 months, highlighting their potential as M&A targets [3][4] - The identified stocks include companies from the health care sector, such as Insmed, Madrigal Pharmaceuticals, Krystal Biotech, Mineralys Therapeutics, and Vera Therapeutics, with varying market capitalizations and year-to-date total returns [5][6][7][8][9]

Core Insights - Bitcoin Well Inc. has acquired 31.36 bitcoin at an average price of $113,314 USD / $157,428 CAD, increasing its total bitcoin reserve to 42.36 BTC with an average purchase price of $110,087 USD / $152,504 CAD [1] - The company plans to allocate the majority of the proceeds from its recent private placement to purchase additional bitcoin in the coming weeks [2] - Bitcoin Well aims to make bitcoin accessible to everyday people, providing modern banking convenience alongside the benefits of bitcoin [3] Company Overview - Bitcoin Well operates Bitcoin ATMs and an Online Bitcoin Portal, which generate cash flow to support its mission of enabling financial independence through bitcoin [3] - The company encourages investors to join its community and stay updated through various social media platforms [3]

Madrigal Pharmaceuticals (NASDAQ: MDGL ) has quickly become a major player in metabolic liver disease treatments with Rezdiffra (resmetirom), which is indicated for F2-F3 MASH. This drug was authorized under accelerated approval in the US and is already showing blockbuster potential. This is despite havingMy name is Myriam Hernandez Alvarez. I received the Electronics and Telecommunication Engineering degree from the Escuela Politecnica Nacional, Quito, Ecuador, the M.Sc. degree in computer science from Ohi ...

Madrigal Pharmaceuticals (NASDAQ: MDGL ) has quickly become a major player in metabolic liver disease treatments with Rezdiffra (resmetirom), which is indicated for F2-F3 MASH. This drug was authorized under accelerated approval in the US and is already showing blockbuster potential. This is despite havingMy name is Myriam Hernandez Alvarez. I received the Electronics and Telecommunication Engineering degree from the Escuela Politecnica Nacional, Quito, Ecuador, the M.Sc. degree in computer science from Ohi ...

Company Developments - Madrigal has made significant progress since the beginning of the year, including new intellectual property (IP) and European Union (EU) approval [3] - The company has entered into a new licensing agreement, indicating active business development and strategic partnerships [3]

Summary of Madrigal Pharmaceuticals FY Conference Call Company Overview - **Company**: Madrigal Pharmaceuticals (NasdaqGS:MDGL) - **Key Product**: Rezdiffra, a treatment for metabolic-associated steatotic liver disease (MASH) Key Highlights 1. **Financial Performance**: - Achieved a revenue of **$213 million** in the last quarter, exceeding expectations and indicating strong market demand for Rezdiffra [4] - Secured **$500 million** in financing to support ongoing operations and expansion efforts [2] 2. **Product Launch and Market Penetration**: - Rezdiffra is reported to have a **7% penetration** into a target population of **315,000 patients** [5] - The launch metrics are reportedly among the best in the last decade, with **80%** of targeted prescribers having written a prescription [4] - Over **23,000 patients** are currently on the drug, indicating strong initial uptake [5] 3. **Intellectual Property Protection**: - Extended intellectual property protection for Rezdiffra until **2045**, providing a long-term competitive advantage [2][13] - This patent is considered the most significant achievement for the company, allowing for strategic business development [14][16] 4. **Clinical Efficacy and Patient Outcomes**: - Real-world data shows that Rezdiffra is exceeding efficacy expectations, with improvements in liver stiffness and fat observed in patients [9][10] - Physicians report positive outcomes, including reversals in fibrosis stages for some patients [10] 5. **Market Dynamics and Competitive Landscape**: - The company is preparing to enter the European market, starting with Germany, targeting a potential **370,000 patients** in the EU [36] - The competitive landscape includes other treatments like GLP-1 receptor agonists, with Madrigal positioned to benefit from potential patient discontinuation of these therapies [26][27] 6. **Business Development Strategy**: - Recently acquired an oral GLP-1 asset from CSPC, which is expected to complement Rezdiffra and enhance its efficacy with lower weight loss requirements [38][39] - The company is focused on expanding its pipeline while maintaining a leadership position in the specialty market [41][47] 7. **Payer Relationships and Pricing Strategy**: - Ongoing discussions with payers regarding market access and pricing strategies, with a focus on long-term value creation [30][32] - Initial contracting with payers began in April 2025, with expectations for growth-to-net management to evolve positively [31] Additional Insights - **Patient Adherence**: Strong adherence rates are reported, attributed to the drug's tolerability and efficacy [11][12] - **Regulatory Approvals**: The company has received European Commission approval, marking a significant milestone for international expansion [33] - **Future Outlook**: The leadership team expresses confidence in building a durable specialty company capable of competing with industry leaders [48] This summary encapsulates the key points discussed during the conference call, highlighting Madrigal Pharmaceuticals' current status, strategic initiatives, and future prospects in the healthcare market.

Group 1 - Madrigal Pharmaceuticals, Inc. will participate in the Morgan Stanley 23 Annual Global Health Care Conference on September 8, 2025, at 7:45 A.M. EDT [1] - The presentation will be available via live webcast and a replay will be accessible after the event [1] Group 2 - Madrigal Pharmaceuticals focuses on developing novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a liver disease with significant unmet medical needs [2] - The company's medication, Rezdiffra (resmetirom), is the first and only FDA and European Commission approved treatment for MASH with moderate to advanced fibrosis (F2 to F3) [2] - An ongoing Phase 3 outcomes trial is assessing Rezdiffra for the treatment of compensated MASH cirrhosis (F4c) [2]