Stoke Therapeutics (STOK) 2025 Conference June 04, 2025 01:25 PM ET Speaker0 Yeah. I mean, it truly does differentiate your medicine. Speaker1 Right. Are you ready? Yep. Okay. We're gonna get started with our next session. I'm Andrew Tsai, senior biotech analyst at Jefferies. Thanks for joining me today. It's my pleasure to have Stokes Interim CEO, Ian Smith, by my side today. Welcome, Ian. Speaker0 Thank you, Andrew. Speaker1 Thank you. Yep. And so maybe spend the next couple minutes discussing Stokes, wha ...

Core Viewpoint - Stoke Therapeutics, Inc. (STOK) has shown a significant price increase of 25.2% over the past four weeks, with a mean price target of $22.38 indicating a potential upside of 132.4% from the current price of $9.63 [1] Price Targets and Analyst Consensus - The average price target for STOK ranges from a low of $15 to a high of $35, with a standard deviation of $6.82, suggesting variability in analyst estimates [2] - The lowest estimate indicates a potential increase of 55.8%, while the most optimistic estimate points to a 263.5% upside [2] - A tight clustering of price targets, indicated by a low standard deviation, suggests a high degree of agreement among analysts regarding the stock's price movement [9] Earnings Estimates and Analyst Optimism - Analysts have shown strong agreement in revising STOK's earnings estimates higher, which correlates with potential stock price increases [11] - The Zacks Consensus Estimate for the current year has increased by 59.1% over the past month, with three estimates going higher and no negative revisions [12] - STOK holds a Zacks Rank 2 (Buy), placing it in the top 20% of over 4,000 ranked stocks based on earnings estimates [13]

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from __________ to ____________ Commission File Number: 001-38938 Stoke Therapeutics, Inc. (Exact Name of Registrant as Specified in its Charter) (State or other jurisd ...

Stoke Therapeutics, Inc. (STOK) came out with quarterly earnings of $1.90 per share, beating the Zacks Consensus Estimate of a loss of $0.37 per share. This compares to loss of $0.57 per share a year ago. These figures are adjusted for non-recurring items.This quarterly report represents an earnings surprise of 613.51%. A quarter ago, it was expected that this company would post a loss of $0.51 per share when it actually produced a loss of $0.18, delivering a surprise of 64.71%.Over the last four quarters, ...

Financial Performance - Revenue recognized from the License and Collaboration Agreement with Biogen for the three months ended March 31, 2025 was $152.4 million, compared to no revenue for the same period in 2024[7] - Net income for the three months ended March 31, 2025 was $112.9 million, or $1.90 per diluted share, compared to a net loss of $26.4 million, or $0.57 per share for the same period in 2024[7] - Total revenue for the first quarter of 2025 was $158.6 million, compared to $4.2 million for the same period in 2024[16] Expenses - Research and development expenses for the three months ended March 31, 2025 were $32.7 million, compared to $22.4 million for the same period in 2024, including a one-time $8.2 million sublicense fee associated with the Biogen agreement[7] - General and administrative expenses for the three months ended March 31, 2025 were $14.7 million, compared to $10.2 million for the same period in 2024[7] Cash Position - As of March 31, 2025, the company had $380.3 million in cash, cash equivalents, and marketable securities, expected to fund operations beyond the second half of 2027 and into launch readiness projected for mid-2028[1] Collaboration with Biogen - The collaboration with Biogen includes an upfront payment of $165 million, with potential milestone payments of up to $385 million and tiered royalties on net sales[3] - The company retains exclusive rights for zorevunersen in the United States, Canada, and Mexico, while Biogen has exclusive commercialization rights for the rest of the world[3] Clinical Trials - The company plans to initiate the Phase 3 EMPEROR study in the second quarter of 2025, with an expected data readout in the second half of 2027[3] - The Phase 3 study will evaluate two loading doses of 70mg followed by two maintenance doses of 45mg over 52 weeks in children and adolescents with Dravet syndrome[4]

Wall Street expects a year-over-year increase in earnings on higher revenues when Stoke Therapeutics, Inc. (STOK) reports results for the quarter ended March 2025. While this widely-known consensus outlook is important in gauging the company's earnings picture, a powerful factor that could impact its near-term stock price is how the actual results compare to these estimates.The stock might move higher if these key numbers top expectations in the upcoming earnings report. On the other hand, if they miss, the ...

Investors might want to bet on Stoke Therapeutics, Inc. (STOK) , as it has been recently upgraded to a Zacks Rank #2 (Buy). This upgrade primarily reflects an upward trend in earnings estimates, which is one of the most powerful forces impacting stock prices.The sole determinant of the Zacks rating is a company's changing earnings picture. The Zacks Consensus Estimate -- the consensus of EPS estimates from the sell-side analysts covering the stock -- for the current and following years is tracked by the sys ...

Stoke Therapeutics, Inc. (STOK) shares ended the last trading session 12% higher at $8.61. The jump came on an impressive volume with a higher-than-average number of shares changing hands in the session. This compares to the stock's 5.6% loss over the past four weeks.The sudden price rise can be attributed to growing investors' optimism related to the company’s progress with the development of its pipeline candidate zorevunersen for treating Dravet syndrome.This company is expected to post quarterly loss of ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number 001-38938 Stoke Therapeutics, Inc. (Exact name of Registrant as specified in its Charter) (State or other jurisdiction of incorporation o ...

Stoke Therapeutics, Inc. (STOK) came out with a quarterly loss of $0.18 per share versus the Zacks Consensus Estimate of a loss of $0.51. This compares to loss of $0.60 per share a year ago. These figures are adjusted for non-recurring items.This quarterly report represents an earnings surprise of 64.71%. A quarter ago, it was expected that this company would post a loss of $0.52 per share when it actually produced a loss of $0.47, delivering a surprise of 9.62%.Over the last four quarters, the company has ...