Core Viewpoint - Greenwich LifeSciences, Inc. has received Fast Track designation from the FDA for its immunotherapy GLSI-100, aimed at preventing breast cancer recurrences in HLA-A*02 positive patients who have completed standard HER2/neu targeted therapy [1][2] Company Overview - Greenwich LifeSciences is a clinical-stage biopharmaceutical company focused on developing GP2, an immunotherapy designed to prevent breast cancer recurrences in patients post-surgery [9][11] - The company is currently conducting a Phase III clinical trial named FLAMINGO-01, which evaluates the safety and efficacy of GLSI-100 in HER2 positive breast cancer patients [7][11] Fast Track Designation - The Fast Track designation allows for more frequent communication between the FDA and the company, potentially leading to earlier drug approval and the ability to submit parts of the Biologic License Application (BLA) as they are completed [2][5] - The designation is granted to drugs that address serious conditions and fill unmet medical needs, with GLSI-100 showing potential to improve invasive breast cancer-free survival [2][4] Clinical Trial Details - FLAMINGO-01 is designed to include approximately 500 HLA-A*02 patients randomized to receive GLSI-100 or placebo, with an interim analysis planned after 14 events of invasive breast cancer [7] - The trial aims to detect a hazard ratio of 0.3 in invasive breast cancer-free survival, providing 80% power if the annual event rate in placebo-treated subjects is 2.4% or greater [7] Previous Clinical Data - In a Phase IIb trial, GLSI-100 demonstrated an 80% or greater reduction in cancer recurrences over five years in HER2/neu 3+ patients, with no serious adverse events reported [6][10] - The immunotherapy was well tolerated, and booster injections every six months prolonged the immune response, indicating a strong safety profile [6][10]

Core Insights - RecycLiCo Battery Materials Inc. has appointed Mohammadali (Mo) Shahsavari as Materials Scientist and Process Engineer to enhance its scientific and engineering capabilities [1][2] - The company aims to transition from a venture-stage battery recycler to a significant player in North America's critical minerals supply chain, focusing on energy security and global competitiveness [1][3] Company Overview - RecycLiCo specializes in critical minerals refining, utilizing advanced hydrometallurgical technologies to process mined ore and upcycle lithium-ion battery materials [4] - The company efficiently recovers battery-ready lithium, cobalt, nickel, and manganese from end-of-life batteries and manufacturing scrap, aligning with the demand for responsible supply chains [4] Personnel Background - Mr. Shahsavari has over seven years of technical experience in materials characterization, electrochemistry, corrosion, and hydrometallurgy, holding a Master of Applied Science in Materials Engineering [2] - His previous role as a Lab Process Engineer at BQE Water involved developing innovative processes for wastewater treatment and resource recovery [2] Strategic Positioning - RecycLiCo is positioning itself at the forefront of the strategic reconfiguration of critical minerals sourcing, recovery, refining, and reuse in North America [3] - The company is focused on scaling its technology for not only lithium-ion battery recycling but also for refining and recovering critical minerals from newly-mined ore, existing stockpiles, and industrial scrap [3]

Core Message - CN is launching its annual public awareness campaign, See Tracks? Think Train® Week, from September 15-19, 2025, to emphasize the importance of safety near rail crossings and the dangers of trespassing on railway property [1][3]. Group 1: Campaign Activities - Uniformed CN Police officers will be available for interviews and will participate in community events throughout the campaign week [2]. - CN is partnering with Operation Lifesaver and local authorities to deliver various online and in-person activities aimed at promoting safe practices and raising awareness about rail crossing safety [4]. Group 2: Safety Importance - Preventable accidents occur annually at rail crossings, and CN emphasizes that safety is a shared responsibility among schools, communities, and media partners [3]. - CN Police Services respond to hundreds of events across Canada and the U.S., focusing on protecting CN property and delivering rail safety presentations to various organizations [5]. Group 3: Commitment to Safety - CN continues to invest in rail safety initiatives and encourages community participation in See Tracks? Think Train® Week activities [4]. - The goal of CN Police Services is to promote safe behaviors and increase awareness of rail safety, aiming to make CN the safest railroad in North America [5].

GRAND FALLS-WINDSOR, Newfoundland and Labrador, Sept. 10, 2025 (GLOBE NEWSWIRE) -- First Atlantic Nickel Corp. (TSXV: FAN) (OTCQB: FANCF) (FSE: P21) ("First Atlantic" or the "Company") is pleased to report a significant expansion of visible awaruite nickel-alloy mineralization at the RPM Zone, part of its 100% owned, district-scale, 30 kilometer-long Atlantic Nickel Project in Newfoundland (the "Atlantic Nickel Project" or the "Project"). RPM Drill hole AN-25-07, the second hole of the Phase 2 program, inte ...

Core Message - CN is emphasizing the importance of rail safety through its annual Rail Safety Week campaign, which aims to raise awareness about safe behaviors near railway crossings and the dangers of trespassing on railway property [3][4]. Group 1: Rail Safety Week Activities - CN Police officers will be available for interviews and will participate in community events across Canada during Rail Safety Week from September 15-19, 2025 [1][2]. - The campaign includes a partnership with Operation Lifesaver and local authorities to deliver various online and in-person activities that promote safe practices and raise awareness about rail crossing safety [4]. Group 2: Importance of Rail Safety - Every year, preventable accidents occur at rail crossings, highlighting that safety is a shared responsibility among schools, communities, and media partners [3]. - CN aims to reduce incidents and save lives by working collaboratively with various stakeholders [3]. Group 3: About CN Police - CN Police Services respond to hundreds of events across eight Canadian provinces and 16 U.S. states, focusing on protecting CN property and delivering rail safety presentations to various organizations [5]. - The CN Police Services are committed to promoting safe behaviors and increasing awareness of rail safety through strategic educational initiatives and targeted operations [5].

Orrön Energy AB (“Orrön Energy”) is pleased to announce the composition of the Nomination Committee for the 2026 Annual General Meeting (“AGM”) to be held on 1 April 2026. The Nomination Committee has been formed with the following members: Aksel Azrac (Nemesia S.à.r.l.)Richard Ollerhead (JNE Partners LLP)Sussi Kvart (Handelsbanken Fonder AB) At the Nomination Committee’s first meeting, Aksel Azrac was elected as Chair of the Nomination Committee. The Nomination Committee shall make recommendations to the 2 ...

Core Viewpoint - Fortuna Mining Corp. is actively advancing its $19 million generative exploration program across its projects in Côte d'Ivoire, Mexico, and Argentina, focusing on identifying new growth opportunities [1][2]. Generative Exploration Highlights - The Guiglo Project in Côte d'Ivoire covers 1,142 square kilometers and includes unexplored areas with favorable geology [3]. - Stream sediment sampling has identified four anomalous catchments, with follow-up soil sampling revealing a significant gold anomaly exceeding 20 parts per billion [4]. - Fieldwork is set to resume in October 2025, including additional sampling and drilling [5]. Tongon North Project, Côte d'Ivoire - The exploration program includes scout drilling of previously untested targets and mapping of artisanal zones [7]. - Preliminary targets are associated with fertile structures extending northeast along Barrick's Tongon Mine [8]. - Fieldwork is expected to restart in November, pending weather conditions [10]. Centauro Project, Mexico - The Centauro Project is located in southeastern Chihuahua and covers 600 hectares, with fieldwork already commenced [11]. - Historical exploration has shown widespread anomalous gold and silver values, indicating a fertile epithermal system [12]. - Recent mapping has confirmed a large silica-capped plateau, suggesting a preserved hydrothermal paleosurface [13]. - A first-pass drill campaign is planned to test the potential of the system at depth [14]. La Carmen Project, Mexico - Early-stage exploration is ongoing at La Carmen, characterized by widespread kaolinite alteration over a 5-kilometer area [18]. - Mapping has identified three main zones indicative of a preserved epithermal system [19]. - Surface access agreements are being secured to commence detailed geological mapping and sampling [20]. Cerro Lindo Project, Argentina - The Cerro Lindo Project is located near Fortuna's Lindero Mine and covers 95 square kilometers, with potential for a high-sulphidation epithermal gold and silver system [21][22]. - Previous sampling has shown extensive gold and silver anomalism, along with significant pathfinder elements [22]. - The Arizaro deposit, part of the Lindero property, has an Inferred Mineral Resource of 32.4 million tons averaging 0.37 g/t Au [24]. Drilling Results - Recent drilling at the Arizaro deposit has yielded significant results, including: - ARD68: 0.69 g/t Au, 0.40% Cu over 22 meters [27] - ARD69: 0.39 g/t Au, 0.19% Cu over 27 meters [27] - ARD71: 0.52 g/t Au, 0.15% Cu over 57 meters [27] - A total of 14 diamond drill holes have been completed, with results received for 7 holes to date [25].

Core Viewpoint - NIO Inc. announced a proposed equity offering of up to 181,818,190 Class A ordinary shares, which includes American depositary shares (ADSs) and ordinary shares, to fund various strategic initiatives [1][3]. Group 1: Equity Offering Details - The equity offering consists of an ADS offering and an ordinary share offering, with allocation based on investor interest [1]. - Underwriters will have a 30-day option to purchase an additional 27,272,729 ADSs, which will be settled solely in ADSs if exercised [2]. - The offering will be conducted under the company's shelf registration statement on Form F-3, which became effective on May 21, 2024 [5]. Group 2: Use of Proceeds - The net proceeds from the equity offering will be used for research and development of core technologies for smart electric vehicles, development of future technology platforms and vehicle models, expansion of the battery swapping and charging network, strengthening the balance sheet, and general corporate purposes [3]. Group 3: Underwriters - Morgan Stanley Asia Limited, UBS Securities LLC, UBS AG Hong Kong Branch, and Deutsche Bank AG Hong Kong Branch are acting as representatives for the underwriters for the equity offering [4]. Group 4: Company Overview - NIO Inc. is a leading company in the global smart electric vehicle market, founded in November 2014, with a mission to shape a sustainable future through innovative technology and exceptional user experience [8]. - The company offers premium smart electric vehicles under the NIO brand, family-oriented vehicles through the ONVO brand, and high-end electric cars with the FIREFLY brand [8].

Core Viewpoint - Q2 Metals Corp. has reported significant progress in its summer 2025 infill drilling campaign at the Cisco Lithium Project, highlighting multiple wide intercepts of spodumene pegmatite, which indicates strong potential for lithium mineralization [2][3][5]. Drilling Results - The Summer Drill Program involved eight holes drilled over a total of 4,603 meters, all of which intercepted pegmatite with visual indications of spodumene mineralization [3][4]. - Notable drill hole results include: - Hole CS25-044 with a continuous intercept of 457.4 meters [4][5]. - Hole CS25-038 encountered 22 spodumene pegmatite intervals, including a 58.9-meter wide interval [5]. - Hole CS25-039 had 13 intervals, with the widest being 108.5 meters [5]. - A total of 46 holes have been drilled to date, amounting to 20,138 meters, with assays pending for the summer campaign [5]. Mineral Resource Potential - The Cisco Project has an Exploration Target estimating potential mineralization of 215 to 329 million tonnes at a grade ranging from 1.0% to 1.38% Li2O, based on the first 40 holes drilled [11][29]. - The mineralized zone spans approximately 1.5 kilometers in northeast-southwest direction, with ongoing drilling aimed at refining the model and defining an initial inferred Mineral Resource estimate [10][20]. Future Plans - The company plans to continue its drilling campaign into the fall and winter, focusing on infill drilling within the main mineralized zone and testing additional outcrop zones [20][30]. - Three drill rigs are currently operational, emphasizing the commitment to advancing the exploration and resource estimation process [5][20]. Company Overview - Q2 Metals Corp. is a Canadian mineral exploration company focused on the Cisco Lithium Project, which consists of 801 claims covering 41,253 hectares in Quebec, Canada [28][29]. - The project is strategically located 6.5 km from the Billy Diamond Highway, facilitating access to infrastructure [28].

Core Viewpoint - Fangzhou Inc. has entered a strategic partnership with Innovent Biologics to integrate AI-driven digital health services with innovative therapies for metabolic diseases and weight management, aiming to enhance patient outcomes in chronic disease care [1][2][4]. Company Overview - Fangzhou Inc. is a leading online chronic disease management platform in China, serving 52.8 million registered users and 229,000 physicians as of June 30, 2025 [10]. - Innovent Biologics specializes in developing and commercializing innovative therapies across various medical fields, including oncology, cardiovascular, and metabolic diseases [9]. Partnership Details - The partnership will combine Fangzhou's AI-enabled "H2H" digital healthcare ecosystem with Innovent's pipeline of novel therapies for diabetes and obesity, creating a new model that integrates AI technology with personalized services [2][4]. - The initial focus of the collaboration will be on diabetes and obesity, utilizing Fangzhou's "XS Core" AI large language model to power five key products aimed at delivering personalized digital care [4][6]. Market Context - China's weight management market is rapidly growing, with JPMorgan estimating that the market for weight management drugs could reach USD 14.9 billion by 2030 [2]. - The Chinese government has prioritized weight management as a public health issue, launching a three-year "Weight Management Year" campaign in 2024 [3]. Product Highlights - Innovent's Mazdutide therapy has shown significant weight reduction and improvements in health markers such as blood pressure and lipids, and it has been recognized as one of the "Top 10 Most Anticipated Medicines" globally for 2025 [5]. Future Plans - The companies plan to deepen their collaboration in AI-powered health management, aiming to expand access to innovative therapies and improve the quality and efficiency of chronic disease care in China [8].