Core Insights - PodcastOne has secured a multi-year agreement with Clint Frazier for the exclusive distribution rights to his podcast "Life After the Show," marking the 19th addition to its network in 2025, bringing the total to 211 podcasts [1][6] Company Overview - PodcastOne is a leading podcast platform that offers a comprehensive solution in sales, marketing, public relations, production, and distribution, boasting over 3.9 billion total downloads and a community of 200 top podcasters [6] - The platform reaches over 1 billion monthly impressions across various channels, including YouTube, Spotify, Apple Podcasts, and iHeartRadio [6] Podcast Content - "Life After the Show" features weekly episodes where Frazier discusses current baseball issues, interviews former teammates and insiders, and shares his personal experiences post-major league career [2][4] - The podcast aims to provide unfiltered stories and insights from Frazier's time with the New York Yankees and his views on contemporary sports [2][3] Strategic Alignment - The partnership with Frazier aligns with PodcastOne's growth strategy to deliver authentic narratives from real individuals, enhancing its content diversity and listener engagement [3]

Core Insights - Integra LifeSciences Holdings Corporation commends the Centers for Medicare & Medicaid Services (CMS) for its Calendar Year 2026 Medicare Physician Fee Schedule and Outpatient Prospective Payment System rules, which include all of Integra's dermal regenerative templates, decellularized dermal scaffolds, and amniotic tissue membranes classified as skin substitutes [1][2] Group 1: Company Overview - Integra LifeSciences is a global medical technology leader focused on restoring lives through innovation in neurosurgery and tissue reconstruction, with a portfolio of differentiated technologies trusted by healthcare professionals [3] - The company offers a diverse range of products, including Integra matrices, PriMatrix, Cytal, and AmnioExcel, utilizing four unique technology platforms for complex wound reconstruction cases [1][3] Group 2: Industry Impact - The new CMS ruling is seen as a pivotal advancement for the industry, allowing for uniform reimbursement rates across care settings, which will expand access to Integra's product portfolio [2] - The company believes that the new policy will reward innovation, quality, and patient outcomes, areas where it has consistently led [2]

SINGAPORE, Nov. 25, 2025 (GLOBE NEWSWIRE) -- GCL Global Holdings Ltd (Nasdaq: GCL) (“GCL” or the “Company”), a leading provider of games and entertainment, today provided an update on management’s expectations for financial results for the fiscal year 2026, ending March 31, 2026. The Company’s anticipated results reflect its continued growth trajectory in the core consumer and gaming-adjacent verticals, underpinned by the integration of Ban Leong Technologies, including its established distribution footprin ...

Core Insights - Nightfood Holdings Inc. has reported a significant increase in temporary equity of approximately $91.5 million, attributed to strategic hotel acquisitions aimed at enhancing its AI-driven robotics model [3] - The company is positioning itself as a leader in the hospitality sector by integrating artificial intelligence and robotics, which is expected to improve operational efficiency and reduce costs [4] - The global service robotics market is projected to exceed $170 billion by 2030, providing a substantial growth opportunity for Nightfood Holdings [4] Company Overview - Nightfood Holdings Inc. is focused on revolutionizing the hospitality industry through AI-powered robotics and strategic hotel acquisitions [4] - The company's business model includes owning hotel properties and offering Robotics-as-a-Service (RaaS), which allows for scalable revenue streams [4] - The recent quarterly results indicate a strong financial position that supports the company's goal of uplisting and further development as a data-centric hospitality automation platform [3] Industry Context - Investors are increasingly prioritizing companies that can demonstrate credible and measurable earnings improvement, particularly in fast-growing sectors like artificial intelligence and service robotics [2] - The hospitality industry is experiencing a shift towards automation, with companies like Nightfood leading the way in setting new operational standards [4]

Core Insights - Worksport Ltd. has launched its new HD3 heavy-duty tonneau cover, which is now available through its expanding B2B dealer network, with production having started in mid-October [1][2][3] - The HD3 cover is priced starting at $869 and is designed for durability and protection, targeting commercial and high-use customers [2][4] - The company plans to focus on dealer sales for the HD3, while also preparing for direct-to-consumer sales in December [3][4] - Worksport's clean-tech products, COR and SOLIS, will open for initial orders on November 28, representing a new revenue stream for the company [5][6] - The company emphasizes that the HD3, SOLIS, and COR products are the result of years of engineering investment and are expected to drive revenue growth and market presence [7][8] Product Details - The HD3 tonneau cover features upgraded materials, reinforced seals, and heavy-duty latching systems, enhancing its ruggedness compared to previous models [2][4] - SOLIS is a solar-integrated truck bed system designed for renewable power applications, while COR is a modular energy storage system for various utility needs [7][8] Strategic Focus - The introduction of the HD3 is seen as a strategic move to enhance Worksport's product offerings in both B2B and B2C channels, aiming for unit sales growth and channel diversification [4][6] - The company is committed to advancing its manufacturing capabilities and expanding its product portfolio in clean energy and automotive accessories [8]

Core Insights - PolyPid Ltd. is participating in a virtual Key Opinion Leader event to discuss the clinical and economic burden of surgical site infections and the therapeutic potential of D-PLEX100 [1][2] Company Overview - PolyPid Ltd. is a late-stage biopharma company focused on improving surgical outcomes through locally administered, controlled, prolonged-release therapeutics [6] - The company utilizes proprietary PLEX technology to enable precise drug delivery at optimal release rates over durations from several days to months [6] Product Information - D-PLEX100 is PolyPid's lead product candidate designed to provide local prolonged and controlled antibacterial activity at the surgical site to prevent surgical site infections (SSIs) [5] - D-PLEX100 demonstrated a statistically significant 58% relative risk reduction in SSI incidence following abdominal colorectal surgery in the Phase 3 SHIELD II trial [5] - The product received Breakthrough Therapy designation from the U.S. FDA for the prevention of SSIs in elective colorectal surgery [5] Upcoming Events - The KOL event titled "The Science and Business Case for D-PLEX100" is scheduled for December 10, 2025, featuring Dr. Steven D. Wexner discussing SSIs and D-PLEX100's role in addressing this unmet medical need [2][3] Future Plans - PolyPid plans to submit a New Drug Application (NDA) for D-PLEX100 in early 2026 following positive Phase 3 results [7] - The company is also developing an innovative pipeline in oncology, obesity, and diabetes [7]

Core Insights - The company has completed an internal investigation regarding improper accounting practices and is releasing preliminary financial results for FY2025 and the first half of FY2026 [1][3][4] Financial Performance - Preliminary unaudited revenue for FY2025 is expected to be $1.6 billion, a 2.6% increase from the previous year [7] - Gross Comparable Store Sales are projected to rise by 7.5%, amounting to an increase of $116.9 million year-over-year [7] - Revenues from BNC First Day programs are anticipated to grow by 25.3%, equating to $119.9 million year-over-year [8] - The expected net loss for FY2025 is projected to be between $(68.0) million and $(62.0) million, an improvement from the previous year's loss [9] - Adjusted EBITDA for FY2025 is expected to range from $55.0 million to $63.0 million, reflecting a significant increase from the prior fiscal year [9] Balance Sheet and Debt Management - Total debt at year-end is expected to be $103.1 million, down from $196.3 million the previous year [10] - The company's net working capital position is projected to improve to positive $188.9 million from $46.1 million last year [10] First Half FY2026 Results - Preliminary revenue for the first six months of FY2026 is expected to be approximately $933.0 million, a 7.8% increase year-over-year [11] - Net income for the first half of FY2026 is anticipated to range from $3.0 million to $8.0 million, a significant improvement over the prior year's loss [11] - Adjusted EBITDA for the first half of FY2026 is expected to be between $32.0 million and $42.0 million [12] Management Commentary and Strategic Outlook - The CEO highlighted strong sales and improved financial metrics driven by the adoption of BNC First Day offerings and disciplined expense management [15] - The company expects continued top-line growth in FY2026 despite market uncertainties, with anticipated Adjusted EBITDA in the range of $65 million to $75 million [16] - Looking ahead to FY2027, the company aims to improve gross margins and grow Adjusted EBITDA by 15% to 20% or more [17]

Core Viewpoint - Reliance Global Group has strategically realigned its Digital Asset Treasury by consolidating its holdings into Zcash (ZEC), reflecting a strong belief in Zcash's long-term potential and its unique position in the digital asset landscape [1][6]. Strategic Decision - The decision to focus on Zcash follows a comprehensive review by the company and the Crypto Advisory Board, which concluded that Zcash offers the most compelling opportunity for a long-term digital asset strategy [2][5]. - Zcash's privacy-centric architecture, built on Bitcoin's success, is viewed as a more attractive value proposition compared to a diversified portfolio of digital assets [2][4]. Zcash Attributes - Zcash combines robust security, optional privacy, and institutional-grade flexibility, distinguishing it from other blockchain networks [3][4]. - Its dual-transaction model allows for both transparent and privacy-centric activities, enabling organizations to maintain confidentiality while meeting regulatory requirements [3][7]. - Zcash has shown resilience during market volatility, appreciating over 1,200% in the past 90 days, indicating growing recognition of its technological advantages [4][6]. Institutional Relevance - The privacy architecture and compliance-ready design of Zcash are gaining traction in enterprise and financial sectors, making it a strategic fit for Reliance's Digital Asset Treasury [4][6]. - Zcash's features, such as selective disclosure and enterprise-grade confidentiality, support organizations in managing sensitive information while adhering to governance standards [7][8]. Leadership and Strategy - The strategic consolidation into Zcash is attributed to the leadership of Blake Janover, who provided renewed clarity and direction to the treasury strategy [6][8]. - The company emphasizes its commitment to clarity, discipline, and long-term value creation through this focused approach [6][8].

Core Insights - Xenon Pharmaceuticals Inc. is set to present multiple research findings at the American Epilepsy Society Annual Meeting (AES 2025) from December 5-9, 2025, focusing on their lead molecule azetukalner for epilepsy treatment [1][5][9] - The presentations will include long-term data from the X-TOLE open-label extension study, which supports the potential for extended seizure freedom with azetukalner [1][5][6] - Additional findings will address the impact of depression on epilepsy patients and new pre-clinical data from the NaV1.1 program targeting Dravet syndrome [1][5][9] Presentation Details - Seven posters will be presented, including: - Long-term safety and efficacy data of azetukalner in adults with focal epilepsy, with a ≥48-month interim analysis from the ongoing 7-year X-TOLE study [6] - Characterization of long-term seizure freedom in the ongoing open-label extension of X-TOLE [6] - Studies on depression symptoms among epilepsy patients and their impact on treatment outcomes [6][5] - A symposium titled "Exploring Depression and Anxiety in Epilepsy" will be held in partnership with the Epilepsy Foundation of America [5] Company Overview - Xenon Pharmaceuticals is a neuroscience-focused biopharmaceutical company dedicated to drug discovery and development of therapeutics for epilepsy and other neurological disorders [9] - The company's lead molecule, azetukalner, is a selective KV7 potassium channel opener currently in Phase 3 clinical trials for epilepsy, major depressive disorder, and bipolar depression [9] - Xenon is also advancing early-stage programs targeting potassium and sodium channels for potential pain treatment [9]

BOSTON, Nov. 25, 2025 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies, today announced that its Phase 2 clinical trial evaluating intranasal foralumab in patients with amyotrophic lateral sclerosis (ALS) has been accepted for inclusion in the ALS MyMatch Program at the Sean M. Healey & AMG Center for ALS at Mass General Brigham. The study, supported by a grant from the ALS Association, wil ...