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Silo Pharma’s PTSD Candidate SPC-15 Achieves Positive Safety Milestone, Paving Way for Accelerated Clinical Trials Under 505(b)(2) Pathway
Globenewswire· 2025-08-19 12:05
Company Overview - Silo Pharma, Inc. is a diversified developmental-stage biopharmaceutical and cryptocurrency treasury company focused on addressing underserved conditions, including stress-induced psychiatric disorders, chronic pain, and central nervous system diseases [6] - The company's portfolio includes innovative programs such as SPC-15 for PTSD, SP-26 for fibromyalgia and chronic pain, and preclinical assets targeting Alzheimer's disease and multiple sclerosis [6] Product Development - Silo Pharma announced positive bioanalytical and safety/toxicology results for its lead asset SPC-15, confirming that its intranasal spray formulation meets safety standards for clinical trials [1][2] - The preclinical study demonstrated that SPC-15, administered at clinical-representative doses, showed local and systemic safety with no toxicities identified, and systemic exposure was comparable to standard oral administration [2] - The company is conducting an IND-enabling GLP-compliant toxicology and toxicokinetic animal study of SPC-15, along with a device study of the formulation-specific microchip-based nasal spray system [4] Regulatory Strategy - The study data supports Silo's planned 505(b)(2) regulatory strategy for the SPC-15 program, which allows the use of previously established safety and efficacy data to streamline the FDA drug approval process and reduce development costs [3] Market Potential - The post-traumatic stress disorder market size reached $1.8 billion in 2024 and is expected to grow to $3.2 billion by 2034, driven by increasing focus on mental health support and the need for personalized treatments and integrated care solutions [5]
24/7 Market News: VENU Exceeds Development Demand Expectations Through Ryan LLC Partnership
Globenewswire· 2025-08-19 12:05
Core Insights - VENU is currently in active discussions with 38 municipalities in the U.S. for potential development of entertainment campuses, significantly exceeding initial targets [1][2][4] - The partnership with Ryan, LLC has been instrumental in accelerating VENU's municipal outreach, with a goal of securing two new development agreements per quarter [2][4][5] - Each finalized development agreement is projected to add between $150 to $300 million to VENU's balance sheet, enhancing its financial position [2][5] - VENU anticipates adding over $5 billion in completed project value within the next 36 to 48 months, indicating strong future growth potential [6][8] Company Overview - Venu Holding Corporation is redefining the live entertainment landscape through a national network of premium amphitheaters, utilizing its Luxe FireSuites model [8] - The company has established partnerships with industry leaders such as AEG and Aramark, and currently has an active development pipeline exceeding $5 billion, with $1 billion already underway [8]
zSpace Empowers Educators with zKnow™: AI-Powered Assistant Delivers Instant Answers, Saving Teachers Valuable Time
Globenewswire· 2025-08-19 12:00
Core Insights - zSpace, Inc. has launched zKnow, an AI assistant designed to enhance the educational experience by providing instant answers to educators regarding immersive learning content and technical resources [1][2][3] - The introduction of zKnow follows the success of zSpace's Career Coach AI, which has received multiple awards, highlighting the company's commitment to meaningful AI integration in education [3][4] Immediate Impact for Educators - zKnow significantly reduces the time educators spend searching for information, allowing them to focus more on student instruction [2][3] - The AI assistant provides context-aware guidance tailored to immersive learning environments, ensuring that educators receive precise and actionable information [3][6] Proven AI Leadership in Education - zSpace's AI solutions have been recognized with prestigious awards, reaffirming the company's leadership in educational technology [3][4] - zKnow is a domain-specific solution, trained on zSpace's content library, ensuring accuracy and alignment with educational standards [4][6] Market Leadership Through Innovation - The launch of zKnow positions zSpace as a leader in the $8.7 billion immersive learning market, addressing the challenge of adoption complexity [7] - zSpace's focus on secure, purpose-built AI resonates with education decision-makers who prioritize student privacy and regulatory compliance [8] Key Features of zKnow - Instant access to a vast array of interactive lessons and curriculum resources [6] - Context-aware guidance that integrates AR/VR technologies with various subject areas [6] - A privacy-first design that complies with educational data governance frameworks [6]
VCI Global Announces US$2 Billion Partnership Secured by Sovereign-Grade Encrypted Infrastructure
Globenewswire· 2025-08-19 11:59
Core Insights - VCI Global Limited has announced a partnership to establish a sovereign-grade infrastructure venture backed by 18,000 BTC, valued at over US$2.16 billion [1][2] - The joint venture will hold a 70% equity stake by VCI Global, focusing on commercialization and infrastructure management while the digital asset partner retains custody of the BTC reserves [2] - The initiative aims to accelerate institutional adoption of cryptocurrency through secure Bitcoin storage, AI computing, and real-world asset monetization [2][5] Company Overview - VCI Global is a cross-sector platform builder that integrates deep technology with financial architecture to create sovereign-ready digital ecosystems [11][12] - The company has expanded its capabilities in sovereign-grade cybersecurity and AI, launching products like Qsecore and QTrustCard [6][10] - VCI Global's mission is to empower governments and institutions in Southeast Asia to scale securely and independently [12] Technological Infrastructure - The Bitcoin reserves will be stored in QuantVault, a proprietary encrypted storage platform that ensures institutional-grade protection [3] - The development roadmap includes creating a Sovereign Reserve Vehicle (SRV) to transform encrypted infrastructure into revenue-generating assets [3][4] - QuantGold, another platform by VCI Global, focuses on secure data monetization and integrates military-grade encryption with blockchain technology [8][9] Market Positioning - With Bitcoin's market capitalization exceeding US$2.32 trillion and limited BTC left to mine, VCI Global positions itself among a select group of Nasdaq-listed companies integrating large-scale Bitcoin reserves with advanced infrastructure [4] - The partnership enhances VCI Global's leadership in sovereign cybersecurity, AI computing, and institutional crypto infrastructure [5][7] - The focus on national-scale digital asset custody and AI-driven analytics aligns with the rising global demand for secure digital asset frameworks [5][7]
Bayport Management Ltd provides a status update
Globenewswire· 2025-08-19 11:48
Group 1 - Bayport Management Ltd has provided a status update regarding its corporate reorganization efforts [1] - The company has notified noteholders about technical breaches related to its outstanding Subordinated Secured Floating Rate Social Notes [1] Group 2 - The announcement includes details about the ongoing Project Blue, which is part of the company's cleansing initiative [2][2]
Final terms for bonds to be listed 20th August 2025
Globenewswire· 2025-08-19 11:31
To Nasdaq Copenhagen A/S 19th August 2025 Announcement no. 68/2025Final terms for bonds to be listed 20th August 2025On 20th August 2025, Jyske Realkredit A/S will be listing a new Covered Bonds (SDO) and a new Mortgage Bond (RO). Final terms for the bonds are attached to this announcement. The full prospectus for the Bonds consist of the attached final terms and the previously disclosed ”Base Prospectus for the issue of Covered Bonds (SDO), Mortgage bonds (“RO”) and Mortgage Bonds (RO) and bonds issued pur ...
Dragonfly Energy and Airstream® Announce Expanded Partnership
Globenewswire· 2025-08-19 11:30
Core Insights - Dragonfly Energy Holdings Corp. has expanded its partnership with Airstream, making Battle Born Batteries standard in Airstream's Model Year 2026 Interstate and Atlas motorized lines, enhancing the product lineup with both standard features and optional upgrades [3][4][8] Company Overview - Dragonfly Energy is a leader in energy storage and battery technology, specializing in lithium battery systems, particularly the Battle Born Batteries brand, which has seen widespread deployment across various applications [10] - The company utilizes a patented dry electrode manufacturing process, enabling chemistry-agnostic power solutions for energy storage systems, electric vehicles, and consumer electronics [10] Product Features - The Advanced Power System includes three BBGC3 LiFePO₄ batteries, providing 10.3 kWh of usable energy at 100% depth of discharge, optimized for longevity and off-grid capability [5][6] - Airstream's new systems support extended off-grid use with features like integrated heating technology, seamless alternator charging, and solar compatibility [5][6] Partnership Dynamics - The collaboration between Dragonfly Energy and Airstream focuses on innovation, reliability, and enhancing off-grid travel experiences, aligning with the growing demand for high-capacity energy solutions [4][8] - Airstream's Vice President of Supply Chain emphasized the importance of partnering with companies that prioritize power independence and quality [4] Market Position - Dragonfly Energy's Battle Born Batteries are now the lithium battery option for all Airstream products, marking a significant step in the integration of advanced energy solutions in recreational vehicles [6][8]
Kelly Announces Participation in Upcoming Investor Conferences
Globenewswire· 2025-08-19 11:30
TROY, Mich., Aug. 19, 2025 (GLOBE NEWSWIRE) -- Kelly (Nasdaq: KELYA, KELYB), a leading global specialty talent solutions provider, today announced the Company will participate in the following upcoming investor conferences: Midwest IDEAS Conference in Chicago on August 26, 2025 Management is scheduled to present at 8:35 a.m. CT and will participate in one-on-one meetings with investors throughout the day. Gateway Conference in San Francisco on September 3, 2025 Management is scheduled to present at 1:00 p. ...
Orezone Intercepts Further High-Grade Mineralization Below Life of Mine Pits Including 1.59 g/t Gold Over 48.00m and 1.09 g/t Gold Over 45.00m
Globenewswire· 2025-08-19 11:30
Core Insights - Orezone Gold Corporation has reported additional drill results from its Bomboré Gold Mine, confirming the continuity of higher-grade mineralization beneath current resource pits, indicating significant exploration potential [1][3][5]. Exploration Results - Approximately 30,000 meters of exploration drilling was completed in H1-2025, with notable results including: - Extension of North Zone footwall mineralization up to 200 meters below current reserve pits, with grades of 2.55 g/t Au over 23.00 meters and 1.14 g/t Au over 29.50 meters [5]. - Extension of the P17S high-grade sub-zone by 300 meters down plunge, with a grade of 7.40 g/t Au over 6.70 meters [5]. - Identification of multiple broad near-surface strike extensions, including 2.22 g/t Au over 14.00 meters and 1.12 g/t Au over 10.00 meters [5]. Future Plans - Drilling will continue in H2-2025, aiming to increase Bomboré's global resource from 5 million ounces to a target of 7 to 10 million ounces, with an overall production increase to 220,000-250,000 ounces per annum [6]. North and P8P9 Zones - The North Zone continues to define and expand mineralized trends along a 3 km strike length, with mineralization associated with specific geological features [6][7]. - The P8P9 Zone has shown potential for wide zones of mineralization, with significant intercepts including 1.09 g/t Au over 45.00 meters within a broader intercept of 0.64 g/t Au over 157.00 meters [11][10]. Selected Drill Highlights - Recent drilling confirmed the down plunge continuity of higher-grade mineralization in the North Hill sub-zone, with intercepts of 1.59 g/t Au over 48.00 meters and 1.97 g/t Au over 16.10 meters [9]. - The P8P9 Zone has been defined over a 1.6 km strike length, with discrete higher-grade lenses within broader low-grade zones [10].
Altimmune Announces FDA Fast Track Designation for Pemvidutide in Alcohol Use Disorder (AUD)
Globenewswire· 2025-08-19 11:30
Pemvidutide is the only drug currently granted Fast Track Designation in AUD RECLAIM, a Phase 2 trial of pemvidutide in AUD, is currently enrolling GAITHERSBURG, Md., Aug. 19, 2025 (GLOBE NEWSWIRE) -- Altimmune, Inc. (Nasdaq: ALT), a late clinical-stage biopharmaceutical company developing peptide-based therapeutics for liver and cardiometabolic diseases, today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to pemvidutide for the treatment of Alcohol Use Disord ...