Recombinant Type III Triple-Helix Collagen Whitepaper
沙利文· 2024-09-29 23:23
FROST & SPC TIPS TOR TESS TOBET CO V A N | --- | --- | --- | |-----------------------------------------------|-------|-------| | | | | | Copyright | | | | ©2024Frost & Sullivan | | | | | | | | ©Dongguan Everon Healthcare Co., Ltd. | | | Recombinant Type III Triple-Helix Collagen Whitepaper | 2024 ◼ Introduction Collagen is an essential structural element of the extracellular matrix, found in all tissues and organs.It does not only provide strength, durability, and elasticity to tissues but also plays a vita ...
Guy Carpenter’s Carol Adams Joins with Oliver Wyman on Healthcare Stop Loss Report
美世· 2024-09-28 01:58
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Economic conditions outlook, September 2024
麦肯锡· 2024-09-28 00:08
Investment Rating - The report does not explicitly provide an investment rating for the industry Core Insights - Executives are less optimistic about current economic conditions compared to earlier in the year, but there is cautious optimism for the upcoming months [2][3] - Geopolitical instability is viewed as the primary risk to both global and domestic growth, with political transitions also being a significant concern [4][9] - Expectations for company performance remain stable, with about half of respondents anticipating an increase in customer demand and 58% expecting profits to rise [19] Economic Conditions Overview - For the first time since March 2020, a majority of executives perceive the global economy as stable rather than improving, with a notable increase in those reporting no change in conditions [3][5] - The share of respondents expecting improvement in the global economy over the next six months is 42%, while 47% expect improvement in their own countries' economies [8] - Concerns about inflation have shifted, with it now being the fifth most-cited global risk, while it remains a primary concern in developing markets [12] Risks to Growth - Geopolitical instability and political transitions are the top cited risks for both global and domestic growth, with 65% of respondents identifying geopolitical instability as a major concern [11][15] - Rising inequality and extreme weather events are increasingly recognized as long-term risks, particularly in Asia-Pacific and India [15][17] Company Performance and Workforce Expectations - Private sector respondents show muted expectations for workforce growth, with an equal likelihood of expecting an increase or decrease in workforce size [19][20] - Industries such as consumer goods, retail, and healthcare are more likely to anticipate a decrease in headcount compared to previous quarters [19]
B2B-KI-Start-ups in der DACH-Region - Ökosystem, Potenziale und Herausforderungen | Germany
麦肯锡· 2024-09-28 00:08
Investment Rating - The report indicates a positive investment outlook for the B2B AI start-up ecosystem in the DACH region, highlighting significant growth potential as companies plan to increase their investments in AI technologies over the next three years [4][5][43]. Core Insights - Approximately 75% of companies in the DACH region are actively engaging with new AI technologies, with a notable trend towards generative AI (GenAI) applications, which are expected to drive further adoption and innovation [5][6][32]. - The DACH region has around 1,000 B2B AI start-ups, but only a small fraction of AI applications in the economy currently come from these start-ups, indicating a substantial opportunity for growth [4][9]. - The majority of start-ups focus on enhancing efficiency in support functions and differentiating core processes, with about one-third leveraging the GenAI trend for applications in marketing, sales, and customer service [4][16][19]. Summary by Sections Investment Trends - 73% of surveyed decision-makers plan to increase their AI investments in the next three years, with a strong focus on readily available solutions from third-party providers [5][6]. - The funding landscape shows that DACH region start-ups have raised over €5 billion, but this is significantly lower compared to the US, where funding is approximately ten times higher per capita [9][15]. Start-up Ecosystem - The DACH region's B2B AI start-up ecosystem is still in its early stages, with over 90% of start-ups in initial funding phases, compared to 80% in the US [9][10]. - Start-ups are primarily concentrated in three key areas: disruptive AI applications, tools for core process differentiation, and efficiency enhancements in support functions [16][19]. Focus Areas - The report identifies three main focus areas for AI applications: 1. Disruptive applications that create new business models (4% of start-ups) 2. Tools for core processes aimed at competitive differentiation (approximately 74% of start-ups) 3. Efficiency improvements in support functions (22% of start-ups) [16][19][20]. - The automotive, manufacturing, and healthcare sectors are highlighted as key industries with significant AI potential, particularly in operations and supply chain management [20][26]. Challenges and Opportunities - Integration of AI solutions into existing IT systems is a major challenge for companies, often taking 9 to 12 months, which can hinder the adoption of start-up innovations [41][42]. - The report emphasizes the need for strong data management and access to funding and talent as critical success factors for start-ups in the DACH region [4][43]. Future Outlook - The DACH B2B AI start-up ecosystem is expected to grow, driven by the increasing demand for specialized AI solutions and the potential for global competitiveness if challenges related to funding and integration are addressed [43][44].
Cooler Finance
Shi Jie Yin Hang· 2024-09-27 23:03
Investment Rating - The report emphasizes the urgent need for sustainable cooling solutions in developing countries, highlighting a significant investment opportunity in this sector, with the market projected to grow to over $600 billion annually by 2050 [9][13][14]. Core Insights - The report identifies that approximately 3.5 billion people live in hot climates, with only 15% having access to air conditioning, indicating a substantial gap in cooling access that needs to be addressed [9][26]. - It stresses that sustainable cooling solutions are essential not only for comfort but also for health, food preservation, and productivity, particularly for vulnerable populations [10][13][30]. - The report outlines that the cooling market in developing economies is expected to double from around $300 billion to $600 billion by 2050, driven by rising temperatures and economic growth [14][15][39]. Summary by Sections 1. The Urgent Need for Sustainable Cooling Solutions in Developing Countries - The report highlights the critical need for sustainable cooling to address adaptation needs and meet Sustainable Development Goals, particularly in developing countries facing extreme heat [9][10][26]. - It notes that rising temperatures and insufficient cooling access lead to health risks and economic losses, emphasizing the importance of sustainable solutions [9][10][27]. 2. Diverse Sources and Sectors Imply Diverse Cooling Financing Needs - The report maps the investment landscape for cooling, estimating significant financing gaps that need to be filled to meet the growing demand for sustainable cooling solutions [10][18]. - It identifies various market segments, including residential and non-residential cooling, and emphasizes the need for tailored financing mechanisms to address these diverse requirements [18][19]. 3. Challenges and Response Strategies for Promoting Sustainable Cooling - The report discusses challenges to private investment in sustainable cooling, including regulatory barriers and lack of awareness about financing options [11][20]. - It proposes strategies to overcome these challenges, such as improving market data, promoting the business case for sustainable cooling, and enhancing policy frameworks [11][20][21]. 4. Financing Solutions and Innovations - The report outlines various financing mechanisms available for sustainable cooling, including revolving funds, risk-sharing facilities, and innovative business models [18][19][23]. - It emphasizes the role of development finance institutions in mobilizing private capital and supporting the transition to sustainable cooling solutions [20][23]. 5. Conclusions and Recommendations - The report concludes that achieving sustainable cooling requires coordinated efforts from governments, private sector stakeholders, and international organizations [11][21]. - It recommends enhancing awareness of business opportunities in sustainable cooling and prioritizing financing for passive cooling strategies [21][23].
Using Post-Double Selection Lasso in Field Experiments
Shi Jie Yin Hang· 2024-09-27 23:03
Industry Research Summary Industry Investment Rating - The report does not provide a specific investment rating for the industry [1][2] Core Findings - Post-double selection Lasso (PDS Lasso) reduces standard errors by less than 1% compared to standard Ancova on average [2] - PDS Lasso does not select variables to model treatment in over half the cases [2] - The method typically selects very few control variables, with a median of 3 controls [9] - In over a quarter of cases, standard errors are slightly larger than with Ancova [9] Methodology and Application - PDS Lasso is commonly used in field experiments with small sample sizes (100-1,000 observations) [7] - The method is particularly relevant for developing countries where survey data often has an average attrition rate of 15% [8] - Researchers typically input a median of 182 controls, but PDS Lasso selects a median of only 3 controls [9] - The treatment regression step is more likely to select control variables when there is attrition [10] Performance Analysis - PDS Lasso leads to minimal changes in treatment estimates, with a median change of 0.01 standard deviations [9] - The median standard error with PDS Lasso is 99.2% of that with Ancova [9] - Cross-validation for selecting the penalty parameter can overfit and result in larger standard errors [11] - PDS Lasso sometimes ends up being less precise than Ancova due to failure to select key variables like the lagged dependent variable [10] Practical Recommendations - Researchers should include the lagged dependent variable in the amelioration set to prevent underfitting [54] - The number of control variables inputted should be judicious, avoiding a "kitchen sink" approach [59] - Missing values in control variables should be carefully handled to avoid sample size reduction [61] - When including treatment interactions, the interacting variable should be included in the amelioration set [75] Limitations and Considerations - PDS Lasso provides minimal power gains on average compared to Ancova [48] - The method is most beneficial when there is differential attrition greater than 5% [50] - Researchers should not anticipate large improvements in power from using PDS Lasso [76] - The double-selection step may not be necessary in many cases, as it often selects variables not strongly correlated with the outcome [69]
Disaggregated Impacts of Growth on Multidimensional Poverty
Shi Jie Yin Hang· 2024-09-27 23:03
Policy Research Working Paper 10930 Public Disclosure Authorized Public Disclosure Authorized Disaggregated Impacts of Growth on Multidimensional Poverty Does the Source of Growth Matter? Francis Mulangu Mokhtar Benlamine Michael Keller Jean-Pascal Nganou Poverty and Equity Global Practice September 2024 Public Disclosure Authorized Public Disclosure Authorized Policy Research Working Paper 10930 Abstract This paper presents comprehensive findings on the relationship between economic growth and poverty. Usi ...
Sierra Leone Circular Economy in Plastics for Sustainable Tourism and Economic Diversification
Shi Jie Yin Hang· 2024-09-27 23:03
Investment Rating - The report does not explicitly provide an investment rating for the industry Core Insights - The tourism sector in Sierra Leone is identified as a significant contributor to plastic waste, particularly single-use plastics, which poses environmental challenges and necessitates a reduction strategy [9][10] - The guidelines aim to assist hotels and restaurants in Sierra Leone in developing their own single-use plastic reduction programs, thereby promoting sustainable tourism and economic diversification [15][14] - The report emphasizes the importance of a systematic approach to managing single-use plastic reduction, which includes self-assessment, planning, policy creation, and progress evaluation [18][39] Summary by Sections Introduction and Background - The production of plastic has increased significantly, leading to environmental issues, with only 15% of plastic waste being recycled globally [9] - The tourism industry is a major generator of plastic waste, particularly single-use plastics, prompting calls for action to reduce their use [9][10] Approach to Managing Single-Use Plastic Reduction - The report outlines a four-stage approach for hotels to manage single-use plastic reduction: self-assessment, creating a reduction plan, establishing a reduction policy, and measuring progress [18] - A total of ten steps are detailed for effective implementation of the reduction strategy [20] Guidelines and Best Practices - The guidelines provide practical advice for hotels to identify and reduce the most frequently used single-use plastic items, such as plastic bottles, bags, cutlery, and straws [11][56] - Strategies include removing unnecessary items, reducing consumption, replacing with reusable alternatives, and ensuring recyclability of remaining items [30][29] Monitoring and Evaluation - Regular monitoring of progress is essential to ensure targets are met and to identify barriers to success [52] - Evaluation of outcomes will help inform future reduction plans and assess the effectiveness of implemented strategies [53] Attachments - Attachment 1 includes a detailed list of frequently used plastics, self-assessment tools, and financial projection tools [55] - Attachment 2 provides alternatives and strategies for reducing specific single-use plastic items [56]
Siemens' Building X Open Platform And Developer Ecosystem
abiresearch· 2024-09-27 22:03
Investment Rating - The report does not explicitly provide an investment rating for the industry or Siemens' Building X platform Core Insights - Siemens' Building X aims to enhance the smart buildings market by promoting open technology solutions, targeting a market where currently less than 5% of buildings are smart [3] - The platform is designed to facilitate interoperability and integration with existing hardware and software, addressing sustainability and net-zero targets as buildings account for over a third of global emissions [3][4] - Building X has already enabled energy savings of approximately US$4 billion for its customers, showcasing its potential impact on operational efficiency [4] Summary by Sections Siemens Building X Brings Openness to the Smart Buildings Market - Siemens is focusing on open technology solutions to accelerate the growth of the smart buildings market, which remains largely untapped [3] - The platform supports hardware-agnostic interoperability and seamless integration with legacy systems, addressing sustainability challenges [3] Building X Open Platform Leverages Developer Ecosystem - The Building X platform allows third-party developers to create applications tailored to specific needs, similar to a smartphone operating system [5] - Siemens provides developer support tools, including SDKs and low-code development options, to foster a robust developer ecosystem [6] The Role of Building X in a Fast-Evolving Smart Buildings Market - Building managers face challenges such as energy efficiency, sustainability regulations, and increased security risks, necessitating flexible management solutions [7][8] - The report highlights the need for real-time data and user-friendly dashboards to optimize building operations [9] Siemens' Answer: Building X - Building X is defined as a digital platform that helps customers digitalize, manage, and optimize building operations, leading to improved sustainability and operational performance [10] - The platform enables energy savings of up to 30% and enhances user experiences through real-time data integration [10] Building X Dashboards - Building X offers flexible dashboards for monitoring various aspects of smart buildings, such as indoor temperature management [13] Building X and Cybersecurity - Cybersecurity is a priority for Building X, with built-in technologies compliant with major standards to protect against vulnerabilities [14] Building X and Siemens Xcelerator - Building X is part of the Siemens Xcelerator, an open digital business platform aimed at accelerating digital transformation for customers [16][17] Building X Case Study: PRODEA Investments - PRODEA Investments utilizes Building X to manage over 380 buildings, focusing on energy efficiency and compliance with EU environmental legislation [19] Building X Open Software Developer Platform and Ecosystem - The launch of Building X marks a shift towards a software-centric approach, emphasizing modularity and integration [20] Developer Platform Features and APIs - Building X provides a rich set of APIs and developer tools to support application development and integration [21][22] Building X Applications and Developer Ecosystem - Currently, there are 12 applications available on the Building X platform, with more in development, indicating a growing ecosystem [23]
Enhance Your Decarbonization Journey With Siemens' Building X
abiresearch· 2024-09-27 22:03
Investment Rating - The report does not explicitly state an investment rating for the industry or the specific companies involved Core Insights - Siemens' Building X platform is positioned as a comprehensive solution for decarbonizing buildings, integrating various sustainability tools to enhance operational efficiency and support net-zero goals [1][15][51] - The building sector is responsible for 40% of global energy demand and one-third of GHG emissions, necessitating a transformative approach to achieve net-zero emissions by 2050 [4][50] - The smart building management software market, which includes sustainable features, is valued at approximately US$39.7 billion in 2023 and is projected to grow to US$136.2 billion by 2032, with a CAGR of 14.7% [10] Summary by Sections Toolkit for Decarbonizing Building Portfolios - The report emphasizes the need for a transformative approach in the building sector to meet net-zero emissions targets by 2050, highlighting the integration of AEC processes and the role of digitalization [4] Market Trends—Sustainability Tools for Smart Building Management Software - There is a growing demand for sustainable energy sources and strict regulations driving the adoption of sustainability tools within Energy Management Systems and Building Management Systems [7][8] Blueprint for Achieving Net-Zero Goals - Businesses are implementing strategies to decarbonize operations to meet regulatory compliance and competitive standards [12] Digitalizing & Decarbonizing with Siemens' Building X Sustainability Manager - Siemens' Building X platform provides a modular suite of applications that drive sustainability through data-driven insights and decision-making [15][18] Building X's Sustainability Features in Action - The Building X platform integrates various applications to enhance building operations, including Energy Manager, Sustainability Manager, Operations Manager, and Comfort AI [19][22] Case Studies - PRODEA Investments aims to exceed 50% of green-certified buildings by the end of 2024, supported by Siemens' Building X platform [38][40] - The University of East London collaborates with Siemens to create a decarbonized campus blueprint by 2030, targeting a 10% reduction in carbon emissions [43][46] - Coherent has transitioned from 0% to 50% renewable energy in less than four years, utilizing Siemens' Building X for emissions reporting and energy management [47][48] Conclusions - The report concludes that the most effective way to reduce carbon emissions is through digitalized building portfolios that identify operational hotspots, leading to cost savings and optimized asset management [50][51]