Core Insights - Shanghai has achieved a significant milestone with over 700 hematopoietic stem cell donations, highlighting the growing awareness and participation in stem cell donation initiatives [1][4] Group 1: Donation Statistics - As of March 25, 2023, Shanghai recorded its 700th hematopoietic stem cell donor, with a total of 704 donations expected by the end of the week [1][3] - The Shanghai Red Cross Society reported that from March 24 to March 28, there will be 8 stem cell donations, indicating a proactive approach to meet the needs of patients [1][4] Group 2: Patient Needs and Challenges - Approximately 4 million blood disease patients exist in China, with 40,000 new leukemia cases annually, over 50% of which are children [4] - Many patients are unable to undergo hematopoietic stem cell transplants due to a lack of matched donors, leading to preventable fatalities [4] Group 3: Historical Context and Initiatives - Shanghai was the first in China to promote non-related hematopoietic stem cell donation in 1992 and achieved the first donation in 1996 [4] - The city pioneered self-collection and registration of donors through online applications and oral mucosa sample collection, making it the only region in China with dual-channel registration [4] - As of March 25, 2025, the Shanghai branch of the national hematopoietic stem cell donor registry has nearly 190,000 registered volunteers [4]