New findings about cancer are forcing clinicians to rethink their approach to preventing the disease https://t.co/KTZp1IxqH1 ...

Health Benefits of Fasting - Fasting is presented as a highly effective treatment for high blood pressure, a leading cause of death and disability [1] - Fasting can reduce insulin resistance and enhance cognitive capacities, potentially affecting depression and anxiety [1] - Fasting mobilizes visceral fat, which is linked to heart disease, cancer, and diabetes [2] - Chemical changes that happen with exercise also occur with fasting, such as increasing EDNF, a neurochemical protecting the brain from Alzheimer's disease [3][4] Societal and Lifestyle Context - The report highlights that 76% of people are overweight or obese, indicating a significant public health challenge [3] - The current environment is designed to promote unhealthy lifestyles, making people fat, sick, and miserable [3] Unique Selling Points of Fasting - Fasting is presented as a unique intervention with benefits beyond weight loss [5] - All human beings have the capacity to fast [4] - Water fasting has shown profound effects on conditions unresolved by medications, including polycystic ovarian syndrome [4]

Philanthropy - Phil Knight donates $2 billion to cancer research [1]

InnovationRx: Phil Knight’s $2 Billion Cancer Gift https://t.co/CY38Obsfm7 https://t.co/IVWD5LrmBW ...

Brandon Blackstock, a talent manager and the former husband of Kelly Clarkson, has died. A statement from the Blackstock family says he died of cancer, adding he bravely fought the disease for more than three years. The family said he passed away peacefully and was surrounded by family.Blackstock, who was also the stepson of country music legend Reeba McIntyre, leaves behind four children, including two children he shares with Kelly Clarkson. The singer and TV host said that she was cancelling the remaining ...

Core Insights - Rigel Pharmaceuticals reported a strong second quarter in 2025, with a 76% year-over-year increase in net product sales, reaching $58.9 million, and a net income of $59.6 million [2][5][7] Financial Performance - Total revenues for Q2 2025 were $101.7 million, comprising $58.9 million in net product sales and $42.7 million in contract revenues from collaborations [5][10] - Net product sales grew significantly, with TAVALISSE sales at $40.1 million (up 52% from $26.4 million in Q2 2024), GAVRETO at $11.8 million (up from $1.9 million), and REZLIDHIA at $7.0 million (up 36% from $5.2 million) [5][11] - For the first half of 2025, total revenues were $155.0 million, with net product sales of $102.5 million, reflecting a 72% increase compared to the same period in 2024 [8][9] Cost and Expenses - Total costs and expenses for Q2 2025 were $40.6 million, an increase from $36.4 million in Q2 2024, primarily due to higher product sales costs and increased R&D expenses [6][9] - The company reported a net income of $59.6 million for Q2 2025, compared to a net loss of $1.0 million in Q2 2024 [7][12] Business Developments - Rigel completed enrollment in the dose escalation part of its Phase 1b study evaluating R289 in patients with relapsed or refractory lower-risk myelodysplastic syndrome (MDS) [2][11] - The company updated its 2025 financial guidance, projecting total revenue of approximately $270 to $280 million, an increase from the previous estimate of $200 to $210 million [10][13] Collaborations and Agreements - Rigel recognized $40.0 million in non-cash revenue from the release of the remaining cost share liability related to its agreement with Eli Lilly for the development of ocadusertib [3][5] - The company continues to receive milestone and tiered royalty payments on future net sales of ocadusertib as part of its agreement with Lilly [3]

Coach Deion Sanders 'cured from cancer' after bladder surgery https://t.co/ytrNg55GdO ...

Health & Sports - University of Colorado head football coach Deion Sanders states he has overcome cancer after bladder removal [1]

Health & Sports Industry - University of Colorado head football coach Deion Sanders announces he has beaten cancer after bladder removal [1]

Philanthropy & Healthcare - Sandy Weill 向西海岸癌症中心捐赠 1 亿美元，用于利用 AI 技术 [1]