Regulatory & Public Health Concerns - The White House suggests the FDA will advise doctors that acetaminophen (Tylenol) use during pregnancy may increase the risk of autism [1] - Health Secretary Robert F Kennedy Jr mentioned vaccines as an area of close examination regarding the cause of autism, despite previous research showing no connection [3][4] - The administration plans to initiate a safety label change on acetaminophen products and launch a national public service campaign [5] - Clinicians will be encouraged to prescribe the lowest effective dose of acetaminophen for the shortest duration necessary for pregnant women [5] Scientific & Medical Community Response - Tylenol's manufacturer strongly disagrees with the White House, stating that a decade of research shows no credible evidence linking acetaminophen to autism [2] - The American College of Obstetricians and Gynecologists maintains that acetaminophen is safe to take during pregnancy [2] - The federal government is allocating $50 million to investigate the causes of autism [3] - Further research is needed to confirm associations between prenatal acetaminophen exposure and neurodevelopmental disorders, including autism, and to determine causality [2]

For more, let's bring in Dr.. Ashish Jaw, uh, dean of Brown University School of Public Health and former White House COVID response coordinator during the Biden administration. Dr.. Jaw, great to have you with us. This physician's notice uh, on acetaminophen for use during pregnancy. It doesn't seem as stringent as perhaps the markets had expected because it says that basically it allows doctors or doesn't allow, but it says you can still take it um, but you should limit it. Um, is that not as as bad as yo ...

President Trump told pregnant women to stop taking Tylenol. Medical groups maintain it is safe. What the research shows about autism, pregnancy and Tylenol. https://t.co/rmVhDpumMX ...

Effective immediately, the FDA will be notifying physicians that the use of said, well, let's see how we say that. As said men if in acetaminophen said, okay, this which is basically commonly known as Tylenol. During pregnancy can be associated with a very increased risk of autism.So taking Tylenol is not good. All right, I'll say it. It's not good.For this reason, they are strongly recommended that women limit Tylenol use during pregnancy unless medically necessary. That's, for instance, in cases of extrem ...

Group 1: Core Claims and Statements - President Trump suggested a connection between Tylenol use during pregnancy and autism, a claim disputed by many medical experts [1] - Trump stated that the FDA will notify doctors about the potential risks of Tylenol during pregnancy, although no supporting evidence was provided [2] - The FDA recently approved a version of leucovorin for a rare metabolic disorder, which may relate to neurological symptoms seen in some autism cases [3] Group 2: Industry Response - Tylenol is produced by Kenvue, which was spun off from Johnson & Johnson in 2023, and the company disagrees with the claim linking Tylenol to autism, stating it is not based in science [4] - Generic versions of acetaminophen are widely available in the market [4] Group 3: Public Health Context - The Trump administration, influenced by Health Secretary Robert F. Kennedy Jr., is under pressure to address rising autism cases in the US [4] - Broader changes to public health agencies, including the CDC, have been made, with critics noting the immunization panel's staffing includes individuals historically critical of vaccines [5]

Healthcare & Regulatory - FDA 将就怀孕期间使用对乙酰氨基酚与自闭症之间的联系向医生提供建议 [1]

FDA will advise doctors about link between autism, acetaminophen use during pregnancy, Trump sayshttps://t.co/P9jkQIRPu9 ...

Core Viewpoint - The Trump administration has drawn an unproven link between acetaminophen use during pregnancy and autism, contradicting existing scientific literature that suggests no causal relationship [1][4][9] Group 1: Acetaminophen and Pregnancy - Acetaminophen, particularly in the form of Kenvue's Tylenol, is widely regarded as a safe option for pain and fever relief during pregnancy when used at recommended doses [2] - Kenvue has expressed strong disagreement with the administration's claims, emphasizing that independent scientific evidence supports the safety of acetaminophen and warns against the health risks posed to expecting mothers if they avoid the drug [3][4] Group 2: Risks of Untreated Conditions - Untreated fever and pain during pregnancy can lead to serious risks for both the mother and infant, including miscarriage, birth defects, and high blood pressure, as noted by the Society for Maternal-Fetal Medicine [4] Group 3: Leucovorin as a Treatment - The Trump administration has also highlighted leucovorin as a potential treatment for autism symptoms, with some early clinical trials indicating its effectiveness in improving symptoms in children with autism spectrum disorder [5] - The FDA announced approval for a version of leucovorin previously made by GSK, although there was a subsequent request to withdraw this notice [6] Group 4: Broader Context of Autism Research - Robert F. Kennedy Jr. has focused on autism within the Health and Human Services department, pledging to identify its causes and eliminate exposures, while also launching extensive research efforts involving numerous scientists [8] - The scientific consensus suggests that autism arises from a complex interplay of genetic and environmental factors, making it improbable that a single cause accounts for the rising rates of the disorder [9]

Core Viewpoint - Kenvue Inc. (KVUE), the parent company of Tylenol, is experiencing a decline in stock price due to concerns raised by the Trump administration linking Tylenol to autism risk, despite existing studies refuting this claim [2][5][6]. Company Overview - Kenvue was spun off from Johnson & Johnson in 2023 and is known for various household products, including Tylenol, Band-Aid, Listerine, and Zyrtec [3]. - Tylenol, containing acetaminophen, has been available over-the-counter in the U.S. since 1960 and is widely used for pain relief and fever reduction [4]. Industry Concerns - Federal health officials are expected to announce concerns regarding the use of acetaminophen by pregnant women, citing research suggesting a potential link to autism [5]. - The CDC reported that the diagnosis rate of autism in American 8-year-olds has increased from one in 150 in 2000 to one in 31 in 2022, highlighting a growing public health concern [8]. Response from Kenvue - Kenvue has stated that acetaminophen does not cause autism, aiming to clarify the safety of their product amidst rising concerns [8].

Core Viewpoint - The article discusses the potential link between paracetamol use during pregnancy and autism, highlighting the lack of substantial evidence to support this claim despite rising autism rates in the US and increased paracetamol consumption [1][2][4]. Group 1: Paracetamol Usage and Autism Correlation - Americans account for over 40% of global paracetamol consumption, spending more than $4 billion annually on acetaminophen products [1]. - Autism rates in the US have increased significantly, from approximately one in 150 children in 2000 to about one in 30 today [1]. - Some studies suggest a correlation between maternal paracetamol use during pregnancy and autism or other neurodevelopmental disorders, but these studies have not definitively proven causation [2][3]. Group 2: Confounding Factors - Factors such as parental genetics, maternal lifestyle, and the underlying reasons for paracetamol use (e.g., viral infections) may confound the observed correlation [3]. - A large study involving 2.5 million children in Sweden found only a marginal increase in autism risk associated with maternal paracetamol use, which disappeared when considering siblings born to the same mothers during pregnancies without paracetamol use [6][8]. Group 3: Health Recommendations - Health authorities, including those in the UK, continue to recommend paracetamol as the safest pain relief option during pregnancy, as other painkillers like ibuprofen may pose risks [9]. - Experts caution that avoiding paracetamol could lead to more significant health issues for both the mother and the developing baby [11][12]. Group 4: Societal Implications - The discussion around a potential link between paracetamol and autism may contribute to stigma against mothers of autistic children, which is a concern among researchers [14]. - The narrative surrounding this issue may serve as a distraction from other controversies, reflecting broader themes in US health policy [16][17].