创新钾离子竞争性酸阻滞剂
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丽珠集团(000513.SZ):JP-1366片注册上市许可申请获受理
Ge Long Hui· 2025-08-15 18:55
Core Viewpoint - Lijun Pharmaceutical Group has received the acceptance notice from the National Medical Products Administration for the domestic production registration of JP-1366 tablets, an innovative potassium ion competitive acid blocker (P-CAB) [1] Group 1: Product Information - JP-1366 tablets work by competitively blocking the K(+) channel of the H(+), K(+)-ATPase (proton pump), inhibiting the binding of K(+) to the proton pump, thereby suppressing gastric acid secretion [1] - The product promotes esophageal mucosal healing and improves reflux symptoms, with a rapid increase in gastric pH and the ability to maintain gastric pH above 4 for an extended period, effectively addressing nighttime acid breakthrough [1] Group 2: Financial Investment - As of the announcement date, the total research and development expenses directly invested in JP-1366 tablets amount to approximately RMB 185.21 million [1]
健康元(600380.SH):JP-1366片药品注册上市许可申请获受理
Ge Long Hui A P P· 2025-08-15 08:48
Core Viewpoint - Health元's subsidiary, Lijun Pharmaceutical Group, has received the acceptance notice from the National Medical Products Administration for the domestic production registration of JP-1366 tablets, an innovative potassium ion competitive acid blocker (P-CAB) [1] Group 1 - JP-1366 tablets work by competitively blocking the K(+) channel of H(+), K(+)-ATPase (proton pump), inhibiting the binding of K(+) to the proton pump, and suppressing gastric acid secretion [1] - The drug promotes esophageal mucosal healing and improves reflux symptoms [1] - JP-1366 tablets can rapidly increase gastric pH levels and maintain gastric pH above 4 for an extended period, effectively addressing nighttime acid breakthrough [1]