Core Viewpoint - Eli Lilly and Company has experienced a significant stock recovery after a sharp decline in August, driven by developments related to tariff negotiations and its strong product performance in the weight loss and diabetes drug market [1][2]. Stock Performance - Eli Lilly's stock surged by 16% during the trading week ending October 3, reaching its highest level since April [1]. - Following a 14% drop on August 7, the stock has increased over 31% year-to-date, with approximately half of this gain occurring recently [2]. Tariff Developments - President Trump announced a 100% tariff on imported branded pharmaceuticals on September 25, but companies investing in U.S. manufacturing would be exempt [3]. - Clarity emerged on September 30 and October 1 when Pfizer announced a deal with the Trump administration, leading to a significant rise in Eli Lilly's shares as it was anticipated that Lilly could secure a similar arrangement [4][5]. Strategic Positioning - Eli Lilly has proactively prepared for potential tariffs by announcing a $27 billion increase in U.S. manufacturing investments and plans to become a net exporter of injectable GLP-1s [6]. - The company is well-positioned to negotiate a tariff-avoiding deal, which has contributed to the recent rise in its stock price [6]. Market Impact - A potential deal similar to Pfizer's could lead to a significant reduction in U.S. drug prices, which may impact revenues, but the concessions are primarily in smaller market segments [7][8]. - Medicaid's spending on Eli Lilly's key drugs, Zepbound and Mounjaro, is relatively low, suggesting that pricing concessions in this area would have minimal impact on overall sales [9]. Future Outlook - The consensus price target for Eli Lilly is approximately $933, indicating an 11% potential upside, with the possibility of further stock price increases if a deal is secured [10].

Group 1 - The impact of pharma tariffs appears to be minimal for large-cap pharmaceutical stocks, while smaller companies without US manufacturing may face more significant challenges [1] - The response from the buy-side community indicates concerns about the negative effects on non-domestic companies that have not relocated manufacturing to the US [2] - Most biotech companies are primarily domestic, which mitigates the overall risk, as those with facilities and investments in the US are less affected by the tariff changes [2][3] Group 2 - The net impact of the current situation is viewed positively for the pharmaceutical sector, despite some uncertainty surrounding biotech companies [2] - The commentary suggests that companies with US-based operations are somewhat insulated from the adverse effects of the tariffs [2]

Core Viewpoint - Britain is actively engaging with the United States regarding pharmaceutical tariffs, aiming for a favorable resolution after President Trump announced a potential 100% tariff on companies unless they establish manufacturing operations in the U.S. [1] Group 1 - The British government is pressing the U.S. on pharmaceutical tariffs [1] - President Trump indicated that a new 100% tariff would be imposed on firms without a manufacturing presence in the U.S. [1]