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糖智药业:为创新药研发供好“糖”
Shang Hai Zheng Quan Bao· 2025-08-01 18:50
Core Insights - Tangzhi Pharmaceutical has achieved a significant breakthrough in the preparation of carbohydrate raw materials, transitioning from milligram to kilogram scale production, with some products reaching over 98% purity, supporting downstream innovative drug development [3][4][5] - The market for nucleic acid raw materials is booming, with projections estimating it to reach a scale of hundreds of billions, driven by the rapid development of mRNA vaccines and the advantages of carbohydrate and nucleic acid drugs [4][5][6] - The company has established partnerships with over a hundred large pharmaceutical enterprises, with some products already in clinical trials, potentially leading to market approval by 2026 [3][4][6] Company Developments - Tangzhi Pharmaceutical has successfully industrialized key raw materials for mRNA drugs, including modified nucleotides and cap analogs, and is focusing on the synthesis and application of these materials [3][4] - The company has developed a biological platform that combines chemical synthesis and biological synthesis, significantly reducing production costs and increasing product purity [5][6] - The company is exploring the production of synthetic heparin, a widely used anticoagulant, through synthetic biology methods, aiming to overcome the limitations of traditional animal-derived sources [7][8] Market Trends - The rapid growth in the nucleic acid drug sector has led to increased demand for carbohydrate raw materials, prompting Tangzhi Pharmaceutical to ramp up production to ensure stable supply [6][8] - The application of AI in enzyme selection has improved research efficiency, allowing for faster identification of optimal candidates for synthesis processes [7] - The company has maintained a 50% annual revenue growth rate since its establishment in 2019, with expectations to surpass 100 million yuan in revenue by 2025 [8]