Core Viewpoint - The article discusses the advancements in single-cell technology and its application in understanding the cellular composition and molecular mechanisms driving cell heterogeneity in plants, particularly focusing on rice as a major crop [2][5]. Group 1: Research Findings - A recent study published in Nature presents a single-cell multi-omics atlas of rice, detailing the chromatin accessibility and RNA expression of 116,564 cells from eight major rice organs [3][6]. - The research identified 54 cell types and described new cellular states, such as a "transitional state" in floral meristem, providing insights into the functional cellular composition of rice at the tissue level [6]. - Key regulatory hubs identified include RSR1, F3H, and LTPL120, which play significant roles in root development, carbon-nitrogen metabolism, and potential plant architecture optimization [6]. Group 2: Technological Contributions - The research team developed the Rice-SCMR, the first intelligent visualization platform for rice single-cell multi-omics, which allows for gene expression and chromatin accessibility searches across 56 annotated cell types [7][10]. - The platform integrates gene regulatory networks, disturbance simulation predictions, and three-dimensional precise localization of GWAS-associated traits, facilitating intelligent design linking genes, cell types, and traits [10]. Group 3: Implications for Agriculture - This study not only provides a unique single-cell multi-omics resource for rice but also enhances the understanding of cell type functions and their potential molecular programs, which could have significant implications for agricultural research and crop improvement [7].