Core Insights - The 21st Beijing Conference on Analytical Testing (BCEIA 2025) is set to open on September 10, 2025, at the China International Exhibition Center in Beijing, celebrating its 40th anniversary [2][4]. Group 1: Opening Ceremony - The opening ceremony is hosted by Zhang Xinrong, Vice President and Secretary-General of the Chinese Society for Analytical Testing [4]. - Jiang Guibin, an academician, delivers the opening address [6]. Group 2: Awards and Recognition - A "Special Contribution Award" is established to honor the founding leaders of BCEIA, with recipients including Yang Hua, Wang Shunchang, Yan Chengde, Wu Bole, and Zhang Yuying [8]. - The award ceremony is presided over by Liu Huwei, Vice President of the Chinese Society for Analytical Testing [8]. Group 3: Conference Reports - The conference marks the 40th anniversary of BCEIA, with Liu Maili, academician and chairman of the academic committee, delivering a speech [11]. - Jiang Guibin, Jonathan V. Sweedler, Xie Xiaoliang, and E Weinan present reports focusing on life sciences, precision medicine, and artificial intelligence, discussing the integration of AI and big data in analytical technologies [12]. Group 4: Development and Achievements - Jiang Guibin reviews the development of BCEIA over 40 years, noting that the exhibition area has expanded from 5,000 square meters to 53,400 square meters, a growth of over ten times [14]. - The number of attendees has increased from approximately 12,000 to 37,456, and exhibitors from 122 to 723, with domestic companies rising from 13 to 680 [14]. - The number of academic forums has expanded from 6 to 18, with 24 academic meetings and 6 frontier seminars, promoting the transition from basic research to application [15]. Group 5: Keynote Presentations - Jonathan V. Sweedler discusses advancements in single-cell mass spectrometry, emphasizing the need to focus on cellular states in specific environments [17]. - Xie Xiaoliang highlights the significance of DNA sequencing and single-cell omics technologies in genomic medicine, advocating for China to develop proprietary sequencing technologies [19][20]. - E Weinan elaborates on the revolutionary impact of AI in various scientific fields, presenting new algorithms for high-dimensional scientific calculations [22]. Group 6: Academic Forums - The conference features 18 academic sub-forums covering topics such as electron microscopy, mass spectrometry, AI-enabled spectroscopy, environmental analysis, and more [24].

Core Insights - The research team successfully decoded the process of leaf senescence in Arabidopsis at the single-cell level, utilizing self-developed single-cell omics and spatiotemporal omics technologies [1][2] - A comprehensive single-cell atlas was constructed, encompassing 20 tissue samples and 913,769 high-quality single-cell nuclear transcriptomes, identifying 38 cell types [1] - The study established aging and youth indices, identifying 1,856 core aging-related genes and 1,875 youth-related genes, enabling quantitative assessment of leaf senescence at single-cell resolution [2] Group 1 - The research revealed key cell types and gene dynamics during leaf senescence, laying the groundwork for future studies on leaf aging [1] - A co-expression gene regulatory network for leaf development was constructed based on aging and youth indices, highlighting several key node genes that may play significant roles in leaf senescence [2] Group 2 - The study found that nutrient transfer during leaf senescence is associated with a complex carbon-nitrogen transport system, with specific genes showing high cell-type specificity in vascular tissues [3] - Key genes responsible for transporting sugars and amino acids from leaves to other parts of the plant were identified, providing insights into the mechanisms of nutrient distribution during leaf aging [3]