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中慧生物2025 年中期业绩报告:商业化加速兑现 研发管线梯次突破
Zhi Tong Cai Jing· 2025-08-29 04:53
Core Viewpoint - Jiangsu Zhonghui Yuantong Biotechnology Co., Ltd. (Zhonghui Bio) reported significant growth in its first interim performance announcement post-IPO, driven by the commercialization of its core product, the quadrivalent influenza virus subunit vaccine, Hui Er Kang Xin, which has shown remarkable commercial success and a reduction in losses compared to the previous year [1][2]. Financial Performance - The company achieved a revenue of 71.12 million yuan in the first half of the year, representing a year-on-year increase of 918.91% [1]. - Sales costs decreased by 18.3% year-on-year, leading to a gross margin increase to 85.5% [1]. - Losses narrowed by 22% year-on-year, indicating ongoing improvements in profitability [1]. Product Development and Market Penetration - The quadrivalent influenza virus subunit vaccine, Hui Er Kang Xin, is the first and only approved quadrivalent influenza subunit vaccine in China, with a 100% pass rate for batch release since its commercialization began in September 2023 [2]. - The product's market penetration has expanded to 30 provinces, with over 1,100 collaborations with district-level disease control centers [2]. - The company is advancing its full population coverage strategy, with plans for a vaccine targeting infants aged 6-35 months expected to receive approval by Q3 2025 [2]. Research and Development Pipeline - The company has a diverse pipeline of 11 vaccines, structured in a gradient development model from late-stage to preclinical [4]. - The rabies vaccine is in the final clinical stage, having completed Phase I trials with promising safety results [3]. - The company is also progressing in other high-demand areas, including the 23-valent pneumococcal polysaccharide vaccine and recombinant RSV vaccine, with various clinical trials underway [4]. Global Expansion Strategy - The company is building its international sales network, with plans to enter markets in Indonesia, Thailand, Uruguay, Canada, Singapore, Mexico, and Hong Kong by 2026 [5]. - In 2024, the company received registration in Macau and is progressing with registration in the Philippines [5]. - The company aims to leverage seasonal differences in flu outbreaks across regions to optimize production capacity [5]. Future Outlook - With the anticipated approval of the low-age indication for the influenza vaccine and the rabies vaccine entering Phase III clinical trials, the company is positioned to strengthen its competitive advantage in the high-growth vaccine sector [5].