Core Viewpoint - The study of Maria Branyas Morera, the world's oldest verified living person, provides insights into aging and longevity, highlighting the potential for distinguishing molecular changes due to aging from those related to health conditions [2][4][6]. Group 1: Research Findings - The research team conducted a high-throughput multi-omics study on Maria Branyas Morera, analyzing her genome, transcriptome, metabolome, proteome, microbiome, and epigenome, with results to be published in Cell Reports Medicine [2][11]. - One major finding is the ability to differentiate molecular changes due to aging from those caused by poor health, as evidenced by her unusually short telomeres without associated age-related diseases [6][11]. - Genetic analysis revealed she possesses mutations that are known to prevent cardiovascular diseases, cognitive decline, and diabetes, while lacking mutations linked to increased risks of certain diseases like Alzheimer's [6][11]. Group 2: Health and Lifestyle Factors - Maria Branyas Morera's blood tests showed low levels of "bad" cholesterol and high levels of "good" cholesterol, indicating efficient lipid metabolism and a strong immune system with low inflammation markers [7]. - Her gut microbiome was found to be similar to that of much younger individuals, with a high abundance of beneficial bacteria, potentially linked to her diet of three servings of yogurt daily [7][8]. - Lifestyle factors such as adherence to a Mediterranean diet and regular exercise may also contribute to her longevity [8].