Core Viewpoint - The Shenzhou 21 mission will conduct the first domestic space experiment with rodents in orbit, focusing on the effects of microgravity on behavior and physiological responses [1] Group 1: Mission Overview - The Shenzhou 21 crew will implement 27 scientific and application projects during their mission, addressing key scientific issues in various fields such as space life sciences, biotechnology, aerospace medicine, space materials science, microgravity fluid physics, and combustion [1] - The mission will involve the use of four mice (two males and two females) to study the impact of weightlessness and confined conditions on their behavior [1] Group 2: Research Focus - The primary research will explore the stress responses and adaptive changes of multiple organ systems in mice under space conditions, with further analysis to be conducted after their return to Earth [1]