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染色体精准编辑
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中国科学院团队实现染色体“精准编辑”
Ren Min Ri Bao· 2025-08-08 21:41
Core Insights - The rapid development and widespread application of genome editing technology in the life sciences provide strong technical support for basic research and application development [1] - A new programmable chromosome editing technology developed by a team from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences allows for precise manipulation of DNA at the kilobase to megabase level in plants and animals, significantly enhancing the scale and capability of eukaryotic genome manipulation [1] Group 1 - The new technology enables multi-gene stacking editing and manipulation of genomic structural variations, opening new pathways for crop trait improvement and genetic disease treatment [1] - This technology is expected to promote the development of new breeding strategies, such as manipulating genetic linkage and regulating recombination frequency for fertility control, as well as eliminating linkage drag to fully exploit the breeding potential of superior alleles in wild germplasm [1] - Reviewers have evaluated this work as a significant breakthrough in the field of genetic engineering, with enormous application potential in breeding and gene therapy [1]