国家流感中心对2025年3月31日-2025年12月14日（以实验日期统计）期间收检的部分流感病毒毒株 进行抗原性分析，结果显示：在A(H1N1)pdm09亚型流感病毒毒株中有97.8%（1091/1115）为 A/Victoria/4897/2022的类似株；在A(H3N2)亚型流感病毒毒株中有41.4%（495/1195）为 A/Croatia/10136RV/2023（鸡胚株）的类似株，71.3%（852/1195）为A/District of Columbia/27/2023（细 胞株）的类似株；在B(Victoria)系流感病毒毒株中有97.5%（313/321）为B/Austria/1359417/2021的类似 株。 人民网北京12月18日电 （记者乔业琼）中国疾控中心最新监测数据显示，2025年第50周（2025年 12月8日至12月14日）南方部分省份流感病毒检测阳性率出现下降；北方省份流感病毒检测阳性率继续 下降。 国家流感中心对2025年3月31日以来收检的部分流感病毒毒株进行耐药性分析，结果显示：在 A(H1N1)pdm09亚型流感病毒毒株中有3.8%（31/807）对神经氨酸酶抑制剂 ...

Core Viewpoint - The article highlights the significant increase in sales of antiviral medications Oseltamivir and Baloxavir due to a rising flu season in China, with sales growth exceeding 100% as flu activity escalates nationwide [1]. Group 1: Flu Activity and Medication Sales - The flu season in China is currently experiencing a rapid increase in activity, with expectations for further escalation [1]. - Sales data indicates a notable rise in demand for antiviral drugs Oseltamivir and Baloxavir, both of which are effective against current flu strains [1]. Group 2: Appropriate Use of Antiviral Medications - Experts emphasize the importance of confirming the pathogen before administering antiviral medications, as some common cold symptoms may be caused by viruses that these medications do not affect [2][3]. - Early treatment is encouraged for confirmed flu infections, ideally within 48 hours of symptom onset for optimal effectiveness [3]. Group 3: Preventive Use and Recommendations - Oseltamivir can be used for prevention in individuals at risk, such as those who have been in close contact with flu patients, but should not be used as a preventive measure after symptoms appear [4]. - Different populations have varying requirements for preventive medication, with high-risk individuals advised to start treatment promptly after exposure [4]. Group 4: Diagnostic Tools and Limitations - Rapid test kits available in pharmacies can assist in initial flu diagnosis but may yield false negatives, necessitating further confirmation through nucleic acid testing if symptoms persist [5][6]. - The sensitivity of antigen tests is lower than that of nucleic acid tests, and negative results do not rule out flu infection, especially in high-risk groups [6].