神经生物学
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揭秘大脑发育中神经回路如何正确连接,中国学者获国际神经生物学奖,将回国加入西湖大学
生物世界· 2025-11-01 03:05
Core Insights - The article highlights the significance of neurobiology research in enhancing human understanding of brain and nervous system functions, indicating that breakthroughs in this field are expected in the coming decades [2][4]. Group 1: Award Announcement - The Eppendorf & Science Neurobiology Prize for 2025 has been awarded to Dr. Lü Cheng, marking the second time this award has been given to a Chinese scholar since its establishment in 2002 [4][7]. Group 2: Research Contributions - Dr. Lü Cheng's award-winning research focuses on the assembly of brain neural circuits, particularly in fruit flies, and includes a study published in Science that reveals how olfactory circuits simplify synaptic partner matching through a "dimensionality reduction" strategy [9][21]. - The research demonstrates that the olfactory circuit in fruit flies reduces the complexity of synaptic pairing from three-dimensional space to a one-dimensional linear search, providing key evidence for universal principles in neural circuit development [9][21]. Group 3: Methodology and Findings - The research team developed a technique to specifically label different types of neurons, allowing them to track individual neuron changes throughout development, revealing that all neurons initially extend their dendrites to the surface of the antennal lobe [14][15]. - Each type of olfactory receptor neuron (ORN) follows a specific arc-like trajectory on the surface, ensuring that they only search for their correct synaptic partners in a defined area, significantly improving the accuracy and efficiency of synaptic pairing [17][18]. - Genetic manipulation experiments confirmed that altering the ORN axon trajectories led to a significant decrease in pairing accuracy, validating the proposed model [20]. Group 4: Broader Implications - The findings extend beyond the fruit fly olfactory system, offering insights into the fundamental principles of neural system development and how the brain constructs complex functions [21]. - The "dimensionality reduction" strategy identified in the research may serve as a universal approach in nature for solving complex problems by simplifying decision-making processes, enhancing system robustness and accuracy [22].
2025年中国脑机接口市场规模将达到38亿元
Huan Qiu Wang· 2025-05-08 06:50
【环球网财经综合报道】脑机接口技术,作为"十四五"规划纲要中重点发展的"脑科学与类脑研究"领域的关键技术之一,被誉为大脑与外部设 备之间的"信息高速公路"。随着人工智能、神经生物学、传感器等技术的提升,脑机接口技术正逐步走进我们的生活。 脑机接口技术实现商用,应用场景广泛。在山东济南的实验室,实验人员通过脑机接口操控无人机,实现人与机器的交互。脑机接口的工作原 理是通过识别脑电波特征,直接读取大脑意图,将其转化为计算机指令。 推动我国脑机接口产业健康发展,应当坚持以应用为导向,特别是当前应以医疗场景为重点领域推进技术创新,从而解决实际临床需求,形成 可持续的发展模式。同时,建立完善的脑机接口技术标准、产品质量标准以及科学伦理规范也至关重要,将为产业发展持续提供规范引领,形 成有序创新环境。(文馨) 医疗领域是脑机接口技术最受关注的领域之一。在山东济南的实验室,实验人员穿戴脑控下肢外骨骼系统,依靠"意念"控制外骨骼,带动下肢 完成行走、抬腿等动作,为瘫痪患者带来了全新希望。 脑机接口技术主要分为非侵入式和侵入式两类。非侵入式脑机接口具有易操作、安全性高等特点,而侵入式脑机接口则可实现更高精度、更复 杂的神经控制 ...