以下文章来源于肥胖世界ObesityWorld ，作者欢迎订阅 肥胖世界ObesityWorld . 《肥胖世界》Obesity World - 同步传真肥胖及代谢国际新学术进展，为医学减重临床、教研人员搭建一座与国际接轨的桥梁，「每医健」旗下内容平台。 袖状胃切除术后，体重反弹并非个例，术后第三年成为反弹高发期！ 2025年11月19日至22日，中华医学会糖尿病学分会第二十七次学术会议（2025 CDS）在陕西西安盛大举行。会上，来自上海交通大学医学院 附属第六人民医院的团队发布了一项回顾性研究，发现接受袖状胃切除术的肥胖患者中，体重回升的发生率高达69.5%，其中超过四成患者的 体重反弹幅度已达到"体重复胖"的医学标准。 肥胖已成为全球范围内对待应对的重要公共健康问题。代谢手术，尤其是袖状胃切除术（SG），是治疗中重度肥胖最常见且有效的方法之 一。但SG术后体重的长期变化，尤其是减重效果不理想和体重复胖（WR），仍影响着手术的持久疗效。此次研究通过长期随访，梳理了SG 术后患者体重变化的整体趋势，并锁定了复胖的高风险时间段，为精准识别高危人群和制定预防策略提供了数据支持。 本研究为回顾性队列分析，纳入20 ...

Core Insights - Obesity is a significant global public health issue, with a retrospective study revealing a 69.5% incidence of weight regain among patients who underwent sleeve gastrectomy (SG) [6][7] - The study identifies the third year post-surgery as a critical period for weight rebound, with 41.7% of patients experiencing a weight regain of 20% or more of their maximum weight loss, meeting the criteria for weight regain (WR) [6][7][8] Study Overview - The research included 676 patients who underwent SG at Shanghai Jiao Tong University from January 2011 to June 2022, with a median follow-up of three years [6][7] - Factors associated with higher postoperative total weight loss percentage (%TWL) included baseline age, initial BMI, male gender, and absence of hypertension [7] - Among 540 patients with complete follow-up at 1, 3, and 5 years, the rate of weight regain increased from 21.7% at year three to 32.6% at year five [7] Weight Change Patterns - Patients were categorized into three groups based on weight change trajectories: significant weight loss, moderate weight loss, and minimal weight loss [7] - The significant weight loss group had higher baseline BMI, waist circumference, fasting insulin, and insulin resistance index (HOMA-IR) compared to the minimal weight loss group [7] Implications for Future Research - The findings provide a scientific basis for identifying high-risk patients and developing preventive strategies against weight regain after SG [8]