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重组裂解酶药物研发
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长春高新技术产业(集团)股份有限公司关于子公司GenSci142胶囊国内生产药品注册临床试验申请获得受理的公告
Core Viewpoint - Changchun High-tech Industry (Group) Co., Ltd. announced that its subsidiary, Jinsai Pharmaceutical, received acceptance for the clinical trial application of GenSci142 capsules, aimed at treating bacterial vaginosis [1][3]. Group 1: Drug Information - Product Name: GenSci142 capsules [1] - Application Type: Domestic production drug registration clinical trial [1] - Indication: Bacterial vaginosis (BV), a common vaginal infection among women of childbearing age [1][2]. - Mechanism of Action: GenSci142 is a recombinant lytic enzyme targeting Gardnerella bacteria, designed to rapidly disrupt bacterial cell walls, leading to quick bacterial death [2]. Group 2: Market Context - Current Treatment Landscape: Existing guidelines recommend antibiotics like metronidazole and clindamycin for BV, but these treatments often lead to recurrence and have issues with antibiotic resistance [1][2]. - Advantages of GenSci142: Compared to traditional antibiotics, GenSci142 offers rapid action, precise bactericidal effects, effective biofilm clearance, low resistance risk, and localized safety [2]. Group 3: Company Impact - Potential Benefits: Successful clinical trial progress could enhance the company's business structure, optimize product offerings, and strengthen its competitive edge in strategic areas [3][4]. - Commitment to Transparency: The company will actively advance the research project and fulfill information disclosure obligations regarding subsequent progress [4].