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长臂猿基因组研究
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中国科学院×中山大学合作发表最新Cell论文
生物世界· 2025-11-08 08:00
Core Insights - The article discusses a significant research study on gibbons, revealing their evolutionary history, population dynamics, and conservation status through extensive genomic sequencing [2][4][9]. Group 1: Research Findings - The research team constructed the most comprehensive gibbon genome dataset to date, covering 18 extant gibbon species and successfully obtaining mitochondrial genomes from three extinct samples, including the "Junzi gibbon" [4]. - The study clarified the controversial evolutionary relationships among the four genera of gibbons: Hylobates, Nomascus, Symphalangus, and Hoolock, resolving a century-old classification issue [4][7]. - Phylogenetic analysis based on ancient mitochondrial DNA placed the extinct Junzi gibbon within the Nomascus genus, negating its status as a separate genus [4][7]. Group 2: Genetic and Ecological Insights - The research indicated that historical changes in gibbon population sizes and habitat suitability were consistent with past climate changes [5]. - Comparative genomics and transgenic mouse experiments identified a deletion of 205 base pairs in the Sonic Hedgehog (SHH) gene, which is linked to the elongated limbs characteristic of gibbons [6][7]. Group 3: Implications for Conservation - The findings advance the understanding of gibbon evolution, biology, and conservation efforts, providing critical information for the protection of threatened gibbon species [9].